Results 1 to 10 of about 63,453 (262)
Molecular Therapy: Nucleic Acids, 2019 Circular RNAs (circRNAs) are a class of single-stranded closed RNA molecules that are formed by precursor mRNA back-splicing or skipping events of thousands of genes in eukaryotes as covalently closed continuous loops.
Duc-Hiep Bach +2 more
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EXCLI Journal : Experimental and Clinical Sciences, 2023 Circular RNAs (CircRNAs) are a class of regulatory RNA transcripts, which are ubiquitously expressed in eukaryotes. CircRNA dysregulation has been shown to disrupt the interaction of the Wnt/β-catenin pathway, which regulates several biological processes
Mina Alimohammadi +7 more
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Circular RNAs in Heart Failure [PDF]
European Journal of Heart Failure, 2017 Abstract Cardiovascular disease, and particularly heart failure, is still a serious health care issue for which novel treatments and biomarkers are needed. The RNA family comprises different subgroups, among which the small-sized microRNAs and the larger long non-coding RNAs have shown some potential to aid in moving personalized ...
Stefan Engelhardt +2 more
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Therapeutic Potential of Circular RNAs as Targets for Cancer Treatment [PDF]
Advanced Pharmaceutical BulletinCircular RNAs (circRNAs) are a novel class of non-coding RNAs primarily generated through a back-splicing processes. These molecules exhibit extensive expression across various tissues, indicating their significant role in numerous biological processes ...
Milad Asadi +8 more
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The role of circular RNAs in brain and stroke
Frontiers in Bioscience-Landmark, 2021 Circular RNAs are single-stranded RNAs which are closed by covalent bonds during splicing. Different from other RNAs, circular RNAs are well known due to their circular structure. In recent years, many researches were conducted to investigate the role of
Yu-Ye Wang +3 more
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Roles of circular RNAs in the pathogenesis and treatment of pancreatic cancer
Frontiers in Cell and Developmental Biology, 2022 Circular RNAs are single-stranded RNAs with a covalently closed structure formed by the process of back-splicing. Aberrant expression of circular RNAs contributes to the pathogenesis of a wide range of cancers. Pancreatic cancer is one of the most lethal
Takahiro Seimiya +2 more
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Circular RNAs in Toxicology [PDF]
Toxicological Sciences, 2020 Abstract Circular RNAs (circRNAs) are a type of closed, long, non-coding RNAs, which have attracted significant attention in recent years. CircRNAs exhibit unique functions and are characterized by stable expression in various tissues across different species.
Yueting Shao, Yiguo Jiang
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Veterinary Sciences, 2023 Circular RNAs are widespread in various species and have important roles in myogenesis. However, the circular RNAs involved in breast muscle development in ducks have not yet been studied.
Jing Liu +6 more
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Circular RNA: A promising new star for the diagnosis and treatment of colorectal cancer
Cancer Medicine, 2021 Background Colorectal cancer (CRC) is one of the most common malignant tumors of the digestive tract. According to the research of circular RNAs in the CRC field, compared with linear RNAs, circular RNAs are a special type of noncoding RNA that are ...
Shunhao Zhang +4 more
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Epigenetic Regulation by Non-Coding RNAs in the Avian Immune System
Life, 2020 The identified non-coding RNAs (ncRNAs) include circular RNAs, long non-coding RNAs, microRNAs, ribosomal RNAs, small interfering RNAs, small nuclear RNAs, piwi-interacting RNAs, and transfer RNAs, etc.
Xiaolan Chen +3 more
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