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International audienceCircular RNA molecules were first described more than 40 years ago. However, it is only recently that the broadness of their phylogenetic distribution has been revealed.
Ferreira-Cerca, Sébastien +1 more
core +3 more sources
KEGG pathways using mRNAs and circular RNAs.
, 2022 Table of enriched KEGG pathways generated from performing KEGG analysis on miRnet using mRNAs and circular RNAs. (XLSX)
Joe W. Chen (12859365) +1 more
core +1 more source
Circular RNAs in body fluids as cancer biomarkers: the new frontier of liquid biopsies
Molecular Cancer, 2021 Cancer is a leading cause of death worldwide, particularly because of its high mortality rate in patients who are diagnosed at late stages. Conventional biomarkers originating from blood are widely used for cancer diagnosis, but their low sensitivity and
Sumeng Wang +11 more
semanticscholar +1 more source
Circular RNA in Diseased Heart
Cells, 2020 Heart disease remains the leading cause of death globally and leads to tremendous socio-economic burden. Despite advances in the field of cardiovascular research, novel theranostics are still in urgent need.
Ying Wang, Bin Liu
doaj +1 more source
Recent development of urinary biomarkers for bladder cancer diagnosis and monitoring
Clinical and Translational Discovery, 2023 Urine‐based liquid biopsy has emerged as a non‐invasive and effective tool for early screening and diagnosis of bladder cancer. This review provides a comprehensive overview of the current urine‐based biomarkers and methods for the detection and ...
Yuchen Zeng +11 more
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Identification of HuR target circular RNAs uncovers suppression of PABPN1 translation by CircPABPN1
RNA Biology, 2017 HuR influences gene expression programs and hence cellular phenotypes by binding to hundreds of coding and noncoding linear RNAs. However, whether HuR binds to circular RNAs (circRNAs) and impacts on their function is unknown. Here, we have identified en
K. Abdelmohsen +10 more
semanticscholar +1 more source
AtCircDB: A tissue-specific database for Arabidopsis circular RNAs
, 2019 © The Author 2017. Published by Oxford University Press. All rights reserved. Circular RNAs are widely existing in eukaryotes. However, there is as yet no tissue-specific Arabidopsis circular RNA database, which hinders the study of circular RNA in ...
Tang, W +9 more
core +1 more source
Detecting circular RNAs: bioinformatic and experimental challenges
Nature reviews genetics, 2016 The pervasive expression of circular RNAs (circRNAs) is a recently discovered feature of gene expression in highly diverged eukaryotes. Numerous algorithms that are used to detect genome-wide circRNA expression from RNA sequencing (RNA-seq) data have ...
L. Szabo, J. Salzman
semanticscholar +1 more source
Profiling of the Predicted Circular RNAs in Ductal In Situ and Invasive Breast Cancer: A Pilot Study
International Journal of Genomics, 2016 The recent advantage obtained by next generation sequencing allows a depth investigation of a new “old” kind of noncoding transcript, the circular RNAs. Circular RNAs are nontranslated RNAs, typically nonpolyadenylated, with a resistance to exonucleases ...
Marco Galasso +7 more
doaj +1 more source
Molecular Therapy: Nucleic Acids, 2018 Circular non-coding RNAs are found to play important roles in biology but are still relatively unexplored as a structural motif for chemically regulating gene function. Here, we investigated whether small interfering RNA (siRNA) with a circular structure
Liangliang Zhang +8 more
doaj +1 more source