Results 11 to 20 of about 63,453 (262)
Characterizing Expression and Regulation of Gamma-Herpesviral Circular RNAs
Frontiers in Microbiology, 2021 Multiple herpesviruses have been recently found to encode viral circular RNAs. Like cellular circular RNAs, these RNAs lack poly-A tails and their 5′ and 3′ ends have been joined, which confers protection from RNA exonucleases. We examined the expression
Takanobu Tagawa +10 more
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Circular RNAs Sparkle in the Diagnosis and Theranostics of Hepatocellular Carcinoma
Frontiers in Genetics, 2021 Exonic circular RNAs (circRNAs) are a novel subgroup of non-coding RNAs, which are generated by a back-splicing mechanism of the exons or introns. Unlike the linear RNA, circRNA forms a covalently closed loop, and it normally appears more abundant than ...
Menglan Wang +4 more
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Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms, 2020 Skeletal muscles have an immense ability to regenerate from the muscle stem cells called satellite cells. The process of skeletal muscle regeneration is called myogenesis, which starts with activation of quiescent satellite cells immediately after muscle injury followed by proliferation and fusion of myoblasts into myotubes.
Arundhati, Das +4 more
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In vitro circularization of RNA [PDF]
RNA Biology, 2016 Over the past 2 decades, different types of circular RNAs have been discovered in all kingdoms of life, and apparently, those circular species are more abundant than previously thought. Apart from circRNAs in viroids and viruses, circular transcripts have been discovered in rodents more than 20 y ago and recently have been reported to be abundant in ...
Sabine, Müller, Bettina, Appel
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Circular RNA: new star, new hope in cancer
BMC Cancer, 2018 Background Circular RNAs are a new class of endogenous non-coding RNA that can function as crucial regulators of diverse cellular processes. The diverse types of circular RNAs with varying cytogenetics in cancer have also been reported.
Zikang Zhang +6 more
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Dysregulation of circular RNAs in inflammation and cancers
Fundamental Research, 2023 Emerging lines of evidence have shown that the production of the covalently closed single-stranded circular RNAs is not splicing errors, but rather a regulated process with distinct biogenesis and turnover. Circular RNAs are expressed in a cell type- and
Jiayu Liu +3 more
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Biogenesis of Circular RNAs [PDF]
Cell, 2014 Circular RNAs are generated during splicing through various mechanisms. Ashwal-Fluss et al. demonstrate that exon circularization and linear splicing compete with each other in a tissue-specific fashion, and Zhang et al. show that exon circularization depends on flanking intronic complementary sequences.
Vicens, Quentin, Westhof, Eric
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Circular RNA identified from Peg3 and Igf2r. [PDF]
PLoS ONE, 2018 Circular RNA is a newly discovered class of non-coding RNA generated through the back-splicing of linear pre-mRNA. In the current study, we characterized two circular RNAs that had been identified through NGS-based 5'RACE experiments.
Bambarendage P U Perera +2 more
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The Expression and Bioinformatics Analysis of Circular RNAs in Endometritis Mouse Uterus Tissues
Molecules, 2022 Previous studies have shown that circular RNAs are directly or indirectly involved in the occurrence of various diseases by regulating gene expression. However, the acting mechanism of circular RNAs in endometritis remains unclear.
Zhiqiang Li +5 more
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Circular RNAs as Promising Biomarkers: A mini-review
Frontiers in Physiology, 2016 The interest in circular RNAs has resurfaced in the past few years. What was considered as junk for nearly two decades is now one of the most interesting molecules.
Nadiah Abu, Rahman Jamal
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