Results 11 to 20 of about 761,097 (299)
Biogenesis of Circular RNAs [PDF]
Cell, 2014 Circular RNAs are generated during splicing through various mechanisms. Ashwal-Fluss et al. demonstrate that exon circularization and linear splicing compete with each other in a tissue-specific fashion, and Zhang et al. show that exon circularization depends on flanking intronic complementary sequences.
Vicens, Quentin, Westhof, Eric
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Circular RNAs as Promising Biomarkers: A mini-review [PDF]
Frontiers in Physiology, 2016 The interest in circular RNAs has resurfaced in the past few years. What was considered as junk for nearly two decades is now one of the most interesting molecules.
Nadiah Abu, Rahman Jamal
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Circular RNAs in Heart Failure [PDF]
European Journal of Heart Failure, 2017 Abstract Cardiovascular disease, and particularly heart failure, is still a serious health care issue for which novel treatments and biomarkers are needed. The RNA family comprises different subgroups, among which the small-sized microRNAs and the larger long non-coding RNAs have shown some potential to aid in moving personalized ...
Devaux, Yvan +7 more
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Optimal design of synthetic circular RNAs
Experimental and Molecular MedicineCircular RNAs are an unusual class of single-stranded RNAs whose ends are covalently linked via back-splicing. Due to their versatility, the need to express circular RNAs in vivo and in vitro has increased.
Seo-Won Choi, Jin-Wu Nam
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Circular RNAs: Non-Canonical Observations on Non-Canonical RNAs
Cells, 2023 The existence of circular RNA (circRNA) research in mainstream science can be attributed to the contemporary synergism of big data and keen attention to detail by several research groups worldwide.
Brett W. Stringer +2 more
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Circular RNAs and their roles in head and neck cancers
Molecular Cancer, 2019 Circular RNAs are abundant endogenous non-coding RNA with no 5′ cap and 3′ polyadenylation tail that modify liner mRNAs and have no terminal structures.
Yang Guo +7 more
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, 2018 Although the type and amount of salivary components are influenced by many factors, due to easy, quick, cheap, and noninvasive sampling method alongside with the existence of the vast majority of the substances found in peripheral blood and urine in it, in recent years saliva has been considered as an ideal biofluid for disease research.
Ghods, Farinaz Jafari
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Molecular Therapy: Nucleic Acids, 2019 Circular RNAs (circRNAs) are a class of single-stranded closed RNA molecules that are formed by precursor mRNA back-splicing or skipping events of thousands of genes in eukaryotes as covalently closed continuous loops.
Duc-Hiep Bach +2 more
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Circular RNA molecules were first described more than 40 years ago. However, it is only recently that the broadness of their phylogenetic distribution has been revealed. Since their discoveries, numerous studies have characterized the molecular mechanisms and function underlying these peculiar molecules, mostly in diverse eukaryotic species.
Hubert F. Becker +1 more
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, 2018 Circular RNAs (circRNAs) constitute a class of RNAs that only recently have come into the focus of the scientific cancer community after it was revealed that they are very abundant, highly conserved across species and show tissue- and developmental stage-specific expression. This tightly regulated, dynamic circRNA expression, in line with expression of
Susanne, Lux, Lars, Bullinger
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