Results 41 to 50 of about 102,540 (304)

Transcriptionally inactive oocyte-type 5S RNA genes of Xenopus laevis are complexed with TFIIIA in vitro [PDF]

open access: yes, 1987
An extract from whole oocytes of Xenopus laevis was shown to transcribe somatic-type 5S RNA genes approximately 100-fold more efficiently than oocyte-type 5S RNA genes.
Eversole-Cire, Pamela   +4 more
core   +1 more source

Circular DNA tumor viruses make circular RNAs [PDF]

open access: yesProceedings of the National Academy of Sciences, 2018
Significance Circular RNAs (circRNAs) play critical physiologic functions, but it is not known whether human DNA viruses express circRNAs. We surveyed Epstein−Barr virus (EBV) and Kaposi’s sarcoma herpesvirus (KSHV) tumors and cell lines, and found specific circRNAs expressed from both viruses.
Tuna Toptan   +8 more
openaire   +2 more sources

Circular RNA circCCNT2 is upregulated in the anterior cingulate cortex of individuals with bipolar disorder

open access: yesTranslational Psychiatry, 2021
Gene expression dysregulation in the brain has been associated with bipolar disorder, but little is known about the role of non-coding RNAs. Circular RNAs are a novel class of long noncoding RNAs that have recently been shown to be important in brain ...
Rixing Lin   +9 more
doaj   +1 more source

Forensic age estimation from human blood using age-related microRNAs and circular RNAs markers

open access: yesFrontiers in Genetics, 2022
Aging is a complicated process characterized by progressive and extensive changes in physiological homeostasis at the organismal, tissue, and cellular levels.
Junyan Wang   +6 more
doaj   +1 more source

Target RNAs strike back on MicroRNAs [PDF]

open access: yes, 2018
MicroRNAs are extensively studied regulatory non-coding small RNAs that silence animal genes throughout most biological processes, typically doing so by binding to partially complementary sequences within target RNAs.
de la Mata, Manuel   +3 more
core   +1 more source

The Epstein Barr virus circRNAome. [PDF]

open access: yesPLoS Pathogens, 2018
Our appreciation for the extent of Epstein Barr virus (EBV) transcriptome complexity continues to grow through findings of EBV encoded microRNAs, new long non-coding RNAs as well as the more recent discovery of over a hundred new polyadenylated lytic ...
Nathan Ungerleider   +14 more
doaj   +1 more source

Circular RNAs in leukemia

open access: yesAging, 2019
In pace with the development of gene sequencing technology and transcriptome research, it has been found that 70 to 90% of the human genome is transcribed into RNAs, while only 2% of RNAs encode proteins. This implies that non-coding RNAs (ncRNAs) may exert vital biological functions and a full analysis of non-coding transcriptomes is needed.
Wu, Zijuan   +3 more
openaire   +2 more sources

Translation of Circular RNAs

open access: yesNucleic Acids Research
Circular RNAs (circRNAs) are covalently closed RNAs that are present in all eukaryotes tested. CircRNAs are less abundantly expressed than mRNAs. Recent RNAseq analyses indicate that more than 800,000 circRNA isoforms exist in humans, which is more than twice the number of currently known mRNA isoforms. CircRNAs are generated through backsplicing that
Giorgi Margvelani   +4 more
openaire   +2 more sources

Back-spliced RNA from retrotransposon binds to centromere and regulates centromeric chromatin loops in maize.

open access: yesPLoS Biology, 2020
In most plants, centromeric DNA contains highly repetitive sequences, including tandem repeats and retrotransposons; however, the roles of these sequences in the structure and function of the centromere are unclear.
Yalin Liu   +5 more
doaj   +1 more source

Genome-Wide Profiling of Circular RNAs in the Rapidly Growing Shoots of Moso Bamboo (Phyllostachys edulis). [PDF]

open access: yes, 2019
Circular RNAs, including circular exonic RNAs (circRNA), circular intronic RNAs (ciRNA) and exon-intron circRNAs (EIciRNAs), are a new type of noncoding RNAs.
Gao, Yubang   +13 more
core  

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