Results 1 to 10 of about 111,170 (313)
The Long Noncoding RNA Gm9866/Nuclear Factor-κB Axis Promotes Macrophage Polarization
Mediators of Inflammation, 2023 Macrophages are a type of immune cells with high levels of plasticity and heterogeneity. They can polarize into M1 or M2 functional phenotypes. These two phenotypes exhibit a dynamic balance during polarization-related diseases and play opposing roles ...
Xiaomin Liao +9 more
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Long noncoding RNA involvement in cancer [PDF]
BMB Reports, 2012 Recent advances in genome and transcriptome analysis haveenabled identification of numerous members of a new class ofnoncoding RNA, long noncoding RNA (lncRNA).
Reo Maruyama & Hiromu Suzuki*
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Regulation of Neuroregeneration by Long Noncoding RNAs [PDF]
Molecular Cell, 2018 In mammals, neurons in the peripheral nervous system (PNS) have regenerative capacity following injury, but it is generally absent in the CNS. This difference is attributed, at least in part, to the intrinsic ability of PNS neurons to activate a unique regenerative transcriptional program following injury.
Rotem Ben-Tov Perry, Igor Ulitsky
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Long noncoding RNA: noncoding and not coded [PDF]
Cell Death Discovery, 2017 Mammalian evolution exhibits extraordinary acceleration in phenotypic complexity while displaying genetic conservation. Indeed, protein-coding genes are 90% identical between mice and human, and the question arises what might be the mechanisms by which phenotypic complexity increases while the number of proteins does not?
Toiber, Debra +2 more
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Neural Regeneration Research, 2022 During acute reperfusion, the expression profiles of long noncoding RNAs in adult rats with focal cerebral ischemia undergo broad changes. However, whether long noncoding RNAs are involved in neuroprotective effects following focal ischemic stroke in ...
Wei Ma +14 more
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Long noncoding RNAs and atherosclerosis [PDF]
Atherosclerosis, 2016 Atherosclerosis is universally recognized as a chronic lipid-induced inflammation of the vessel wall in response to dyslipidemia and haemodynamic stress involving dysfunction and activation of resident vascular cells as well as infiltration of leukocytes.
Tian Zhou +3 more
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Cytokines and Long Noncoding RNAs [PDF]
Cold Spring Harbor Perspectives in Biology, 2017 Cytokines and long noncoding RNAs (lncRNAs) are intertwined in the regulatory circuit controlling immunity. lncRNA expression levels are altered following cytokine stimulation in a cell-type-specific fashion. lncRNAs, in turn, regulate the inducible expression of cytokines following immune activation.
Susan, Carpenter +1 more
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The Landscape of Noncoding RNA in Pulmonary Hypertension
Biomolecules, 2022 The transcriptome of pulmonary hypertension (PH) is complex and highly genetically heterogeneous, with noncoding RNA transcripts playing crucial roles.
Lin Deng +4 more
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Long Noncoding RNAs in Cholangiocarcinoma [PDF]
Hepatology, 2021 Cholangiocarcinoma (CCA) is the second primary hepatic malignancy after hepatocellular carcinoma. CCA is characterized by its aggressiveness and poor prognosis associated with limited therapeutic options. Thus, a better understanding of molecular pathogenesis of CCA together with the identification of robust biomarkers and therapeutic targets is still ...
Aude Merdrignac +2 more
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Non‐coding RNA and cholesteatoma
Laryngoscope Investigative Otolaryngology, 2022 Objective Cholesteatoma is a challenging chronic pathology of the middle ear for which pharmacologic therapies have not been developed yet. Cholesteatoma occurrence depends on the interplay between genetic and environmental factors while master ...
Ivan Jovanovic +3 more
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