Results 21 to 30 of about 8,401,372 (300)
Long Noncoding RNAs in Cholangiocarcinoma [PDF]
Hepatology, 2021 Cholangiocarcinoma (CCA) is the second primary hepatic malignancy after hepatocellular carcinoma. CCA is characterized by its aggressiveness and poor prognosis associated with limited therapeutic options. Thus, a better understanding of molecular pathogenesis of CCA together with the identification of robust biomarkers and therapeutic targets is still ...
Aude Merdrignac +2 more
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Long noncoding RNA turnover [PDF]
Biochimie, 2015 Most RNAs transcribed in mammalian cells lack protein-coding sequences. Among them is a vast family of long (>200 nt) noncoding (lnc)RNAs. LncRNAs can modulate cellular protein expression patterns by influencing the transcription of many genes, the post-transcriptional fate of mRNAs and ncRNAs, and the turnover and localization of proteins.
Je-Hyun, Yoon +2 more
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Immunobiology of Long Noncoding RNAs [PDF]
Annual Review of Immunology, 2017 The discovery of long noncoding RNAs (lncRNA) has provided a new perspective on gene regulation in diverse biological contexts. lncRNAs are remarkably versatile molecules that interact with RNA, DNA, or proteins to promote or restrain the expression of protein-coding genes. Activation of immune cells is associated with dynamic changes in expression of
Atianand, Maninjay K. +2 more
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애기 장대에서 잎의 노화 관련 long noncoding RNA (lncRNA)의 조절 역할의 글로벌 분석
, 2021 식물,노화,애기장대,전사체,Long noncoding RNA,lncRNA,leaf senescence,Arabidopsis, senescence-associated long noncoding RNA ...
Jungyeon Kim
core +1 more source
Panning for Long Noncoding RNAs [PDF]
Biomolecules, 2013 The recent advent of high-throughput approaches has revealed widespread transcription of the human genome, leading to a new appreciation of transcription regulation, especially from noncoding regions. Distinct from most coding and small noncoding RNAs, long noncoding RNAs (lncRNAs) are generally expressed at low levels, are less conserved and lack ...
Li Yang, Xiao-Ou Zhang, Shanshan Zhu
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Assessing recent selection and functionality at long noncoding RNA loci in the mouse genome [PDF]
, 2015 This work was supported by the Biotechnology and Biological Sciences Research Council and The Wellcome Trust. A.N. was supported by the Swiss National Science Foundation (Grant: PZ00P3_142636). H.K. was supported by the European Research Council Starting
Ness, Rob W +26 more
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Long noncoding RNAs and neuroblastoma
Oncotarget, 2015 Neuroblastoma is a disease that affects infants and despite intense multimodal therapy, high-risk patients have low survival rates (
Gaurav Kumar, Pandey +1 more
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Long noncoding RNA study: Genome-wide approaches
Genes and Diseases, 2023 Long noncoding RNAs (lncRNAs) have been confirmed to play a crucial role in various biological processes across several species. Though many efforts have been devoted to the expansion of the lncRNAs landscape, much about lncRNAs is still unknown due to ...
Shuang Tao +6 more
doaj +1 more source
Long Noncoding RNAs in Atherosclerosis
Journal of Atherosclerosis and Thrombosis, 2016 Long noncoding RNAs (lncRNAs) were a group of non-protein-coding RNAs ＞200 nucleotides and participated in biological processes and pathophysiological conditions in vivo or in vitro. Recently, more and more lncRNAs interfering with the progress of atherosclerosis were identified and characterized in the atherogenic cells such as vascular smooth muscle ...
Jian, Liguo +3 more
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, 2022 Long noncoding RNAs (lncRNAs) play critical regulatory roles in human development and disease. Although there are over 100,000 samples with available RNA sequencing (RNA-seq) data, many lncRNAs have yet to be annotated.
Kwon, Euijin +5 more
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