Results 1 to 10 of about 16,781,272 (315)

MiRNA-related metastasis in oral cancer: moving and shaking

open access: yesCancer Cell International, 2023
Across the world, oral cancer is a prevalent tumor. Over the years, both its mortality and incidence have grown. Oral cancer metastasis is a complex process involving cell invasion, migration, proliferation, and egress from cancer tissue either by ...
Meghdad Eslami   +11 more
doaj   +1 more source

MALAT1 and MIAT as Emerging Biomarkers for Diabetic Retinopathy: A Systematic Review and Meta-Analysis

open access: yesInternational Journal of Medical Students
Background: Diabetic retinopathy (DR) is a leading cause of preventable blindness, affecting nearly one-fourth of diabetic patients worldwide. Early diagnosis remains a major challenge due to reliance on labour-intensive, clinician-dependent fundoscopy.
Saransh Gupta   +5 more
doaj   +1 more source

Long non-coding RNA expression profile in cytogenetically normal acute myeloid leukemia identifies a distinct signature and a new biomarker in NPM1-mutated patients

open access: yesHaematologica, 2017
Long non-coding RNAs are defined as transcripts larger than 200 nucleotides but without protein-coding potential. There is growing evidence of the important role of long non-coding RNAs in cancer initiation, development and progression. In this study, we
Etienne De Clara   +13 more
doaj   +1 more source

Long Non-coding RNA Expression Profiling Identifies a Four-Long Non-coding RNA Prognostic Signature for Isocitrate Dehydrogenase Mutant Glioma

open access: yesFrontiers in Neurology, 2020
Background: Isocitrate dehydrogenase (IDH) mutant is one of the most robust and important genetic aberrations in glioma. However, the underlying regulation mechanism of long non-coding RNA (lncRNA) in IDH mutant glioma has not been systematically ...
Yusheng Chen   +3 more
doaj   +1 more source

Non-coding RNAs in primary liver cancer

open access: yesFrontiers in Medicine, 2015
Hepatocellular carcinoma (HCC) is a primary malignancy of the liver with poor prognosis and limited therapeutic options. Over the past few years, many studies have evaluated the role of non-coding RNAs (ncRNAs) in hepatocarcinogenesis and tumour ...
Michele eGhidini   +3 more
doaj   +1 more source

Neuid: A Novel Neuron‐Enriched LncRNA that Connects Epigenetic Gene Silencing to Alzheimer's Disease

open access: yesAdvanced Science
The increasing evidence that non‐coding RNAs can become deregulated during pathogenesis is dramatically expanding the space for drug discovery beyond the protein‐coding genome.
Ranjit Pradhan   +17 more
doaj   +1 more source

Long non-coding RNA DANCR, a prognostic indicator, promotes cell growth and tumorigenicity in gastric cancer

open access: yesTumor Biology, 2017
Gastric cancer remains the third leading cause of cancer-related mortality worldwide, and proliferation of gastric cancer represents the major reason for its poor prognosis.
Yan-Ping Hao   +3 more
doaj   +1 more source

The Role of Non-Coding RNA in the Pathogenesis of Hypertensive Nephropathy

open access: yesCells
Hypertensive nephropathy (HN) is a leading cause of chronic kidney disease and end-stage renal disease worldwide and results from the long-term effects of hypertension on renal structure and function.
Paulina Plewa   +5 more
doaj   +1 more source

High-confidence Mapping and Clustered Patterns of LncRNA-associated SNP Reveal Recurrent Non-coding Variants in Colorectal Cancer Transcriptomes [PDF]

open access: yesJournal of Genetic Resources
Long non-coding RNAs (lncRNAs) are important regulators of gene expression and cellular homeostasis, yet sequence-level variation within these transcripts remains poorly characterized in colorectal cancer (CRC).
Maryam Esmaeili, Malek Hossein Asadi
doaj   +1 more source

Non-coding RNA-mediated regulation of seed endosperm development

open access: yesFrontiers in Plant Science
The endosperm, a triploid nutritive tissue in seeds, plays pivotal roles in embryo development, grain yield and quality. Recent advances highlight non-coding RNAs (ncRNAs) as central regulators of endosperm development, which integrate epigenetic ...
Xinqi Wei   +6 more
doaj   +1 more source

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