Results 41 to 50 of about 17,485,262 (316)

Long non‐coding RNA MALAT1 regulates retinal neurodegeneration through CREB signaling

EMBO Molecular Medicine, 2016
The nervous and vascular systems, although functionally different, share many common regulators of function maintenance. Long non‐coding RNAs (lncRNAs) are important players in many biological processes and human disorders.
Jin Yao, Xiao‐Qun Wang, Yu‐Jie Li, Kun Shan, Hong Yang, Yang‐Ning‐Zhi Wang, Mu‐Di Yao, Chang Liu, Xiu‐Miao Li, Yi Shen, Jing‐Yu Liu, Hong Cheng, Jun Yuan, Yang‐Yang Zhang, Qin Jiang, Biao Yan   +15 more
doaj   +2 more sources

A hepatitis C virus cis-acting replication element forms a long-range RNA-RNA interaction with upstream RNA sequences in NS5B [PDF]

, 2008
The genome of hepatitis C virus (HCV) contains cis-acting replication elements (CREs) comprised of RNA stem-loop structures located in both the 5' and 3' non-coding regions (NCR), and in the NS5B coding sequence.
Diviney, Sinéad, Elliot, R., Evans, David John, Evans, D., Armstrong, V, Tuplin, Andrew, Evans, D.J., Struthers, Madeleine, Struthers, M., Elliott, Richard M., Diviney, S., Tuplin, A., Armstrong, V., Struthers, M, Simmonds, Peter, Elliott, Richard Michael, Armstrong, Victoria, Tuplin, A, Evans, David J., Simmonds, P., Diviney, S, Elliott, R.M., Simmonds, P, Evans, David John; id_orcid   +23 more
core   +1 more source

Long Non-Coding RNA Signatures in Lymphopoiesis and Lymphoid Malignancies

, 2023
Lymphoid cells play a critical role in the immune system, which includes three subgroups of T, B, and NK cells. Recognition of the complexity of the human genetics transcriptome in lymphopoiesis has revolutionized our understanding of the regulatory ...
Mahdi Zavvar, Mahmoud Vahidi, Mojgan Mohammadimehr, Mahdi Ghorbani, Davood Bashash, Hamed Baghdadi, Mehdi Shakouri Khomartash, Nazanin Ahmadi, Reza Heidari   +8 more
core   +1 more source

Long non-coding RNA and diseases [PDF]

Jichu yixue yu linchuang
Long non-coding RNA (lncRNA) is a class of endogenous non-coding RNA with a length of more than 200 nt. Due to lack of open reading frame (ORF), they lack the ability to directly encode proteins, but they play a crucial role in gene regulation.

doaj   +1 more source

Human cancer long non-coding RNA transcriptomes. [PDF]

PLoS ONE, 2011
Once thought to be a part of the 'dark matter' of the genome, long non-coding RNAs (lncRNAs) are emerging as an integral functional component of the mammalian transcriptome.
Ewan A Gibb, Emily A Vucic, Katey S S Enfield, Greg L Stewart, Kim M Lonergan, Jennifer Y Kennett, Daiana D Becker-Santos, Calum E MacAulay, Stephen Lam, Carolyn J Brown, Wan L Lam   +10 more
doaj   +1 more source

An autophagy‐related long non‐coding RNA signature for glioma

FEBS Open Bio, 2019
Glioma is one of the most common types of malignant primary central nervous system tumor, and prognosis for this disease is poor. As autophagic drugs have been reported to induce glioma cell death, we investigated the potential prognostic role of ...
Fangkun Luan, Wenjie Chen, Miao Chen, Jun Yan, Hao Chen, Haiyue Yu, Tieqi Liu, Ligen Mo   +7 more
doaj   +1 more source

Role of Non-Coding RNAs in Colorectal Cancer: Focus on Long Non-Coding RNAs

International Journal of Molecular Sciences, 2022
Colorectal cancer is one of the most common causes of cancer-related deaths worldwide. Despite the advances in the knowledge of pathogenetic molecular mechanisms and the implementation of more effective drug treatments in recent years, the overall survival rate of patients remains unsatisfactory.
Lulli, Matteo, Napoli, Cristina, Landini, Ida, Mini, Enrico, Lapucci, Andrea   +4 more
openaire   +3 more sources

The Role of Long Non-Coding RNAs in Endometriosis [PDF]

International Journal of Molecular Sciences, 2021
Endometriosis is a chronic gynecological disorder affecting the quality of life and fertility of many women around the world. Heterogeneous and non-specific symptoms may lead to a delay in diagnosis, with treatment options limited to surgery and hormonal therapy.
Quanah J. Hudson, Katharina Proestling, Alexandra Perricos, Lorenz Kuessel, Heinrich Husslein, René Wenzl, Iveta Yotova   +6 more
openaire   +2 more sources

MALAT1 Long Non-Coding RNA: Functional Implications

, 2020
The mammalian genome is pervasively transcribed and the functional significance of many long non-coding RNA (lncRNA) transcripts are gradually being elucidated.
Disha Aggarwal, David L. Spector, Gayatri Arun   +2 more
core   +1 more source

Crosstalk between Long Non-Coding RNA and Spliceosomal microRNA as a Novel Biomarker for Cancer

, 2023
Non-coding RNAs (ncRNAs) play diverse roles in regulating cellular processes and have been implicated in pathological conditions, including cancer, where interactions between ncRNAs play a role.
Maram Arafat, Ruth Sperling
core   +1 more source