Results 41 to 50 of about 16,781,272 (315)

Long Non-Coding PROX1-AS1 Expression Correlates with Renal Cell Carcinoma Metastasis and Aggressiveness

, 2021
Long non-coding RNAs (lncRNAs) can be specifically expressed in different tissues and cancers. By controlling the gene expression at the transcriptional and translational levels, lncRNAs have been reported to be involved in tumor growth and metastasis ...
Karolina H. Czarnecka-Chrebelska, Dmitry O. Korolev, Andrey Z. Vinarov, Andrey A. Zamyatnin, Yulia Svetikova, Ekaterina B. Kuznetsova, Sofya V. Maryanchik, Alessandro Parodi, Nataliya Potoldykova, Marina V. Nemtsova, Magdalena Rudzinska   +10 more
core   +1 more source

Long non-coding RNA and diseases [PDF]

Jichu yixue yu linchuang
Long non-coding RNA (lncRNA) is a class of endogenous non-coding RNA with a length of more than 200 nt. Due to lack of open reading frame (ORF), they lack the ability to directly encode proteins, but they play a crucial role in gene regulation.

doaj   +1 more source

The G3BP1-UPF1-Associated Long Non-Coding RNA CALA Regulates RNA Turnover in the Cytoplasm

, 2022
Besides transcription, RNA decay accounts for a large proportion of regulated gene expression and is paramount for cellular functions. Classical RNA surveillance pathways, like nonsense-mediated decay (NMD), are also implicated in the turnover of non ...
Jaé, Nicolas Christopher, Wittig, I., Andreas W. Heumüller, Knau, A., Youssef Fouani, Aslan, Galip S., Heumüller, Andreas W., Galip S. Aslan, Aslan, G., Dimmeler, S., Fouani, Youssef, Fouani, Y., Andrea Knau, Mueller-McNicoll, M., Michaela Müller-McNicoll, Müller-McNicoll, Michaela, Knau, Andrea, Jaé, Nicolas, Ilka Wittig, Heumüller, Andreas, Wittig, Ilka, Heumueller, A., Jae, N., Kirchhof, Luisa, Stefanie Dimmeler, Dimmeler, Stefanie, Nicolas Jaé, Kirchhof, L., Luisa Kirchhof   +28 more
core   +1 more source

Post-Transcriptional Regulation through Long Non-Coding RNAs (lncRNAs)

, 2021
The discovery of thousands of non-coding RNAs (ncRNAs) pervasively transcribed from the eukaryotic genome has revolutionized the “central dogma” of biology and shifted the attention on the role of RNAs as regulatory molecules, more than simply ...
Giuseppina Pisignano, Michael Ladomery
core   +1 more source

An autophagy‐related long non‐coding RNA signature for glioma

FEBS Open Bio, 2019
Glioma is one of the most common types of malignant primary central nervous system tumor, and prognosis for this disease is poor. As autophagic drugs have been reported to induce glioma cell death, we investigated the potential prognostic role of ...
Fangkun Luan, Wenjie Chen, Miao Chen, Jun Yan, Hao Chen, Haiyue Yu, Tieqi Liu, Ligen Mo   +7 more
doaj   +1 more source

A hepatitis C virus cis-acting replication element forms a long-range RNA-RNA interaction with upstream RNA sequences in NS5B [PDF]

, 2008
The genome of hepatitis C virus (HCV) contains cis-acting replication elements (CREs) comprised of RNA stem-loop structures located in both the 5' and 3' non-coding regions (NCR), and in the NS5B coding sequence.
Diviney, Sinéad, Elliot, R., Evans, David John, Evans, D., Armstrong, V, Tuplin, Andrew, Evans, D.J., Struthers, Madeleine, Struthers, M., Elliott, Richard M., Diviney, S., Tuplin, A., Armstrong, V., Struthers, M, Simmonds, Peter, Elliott, Richard Michael, Armstrong, Victoria, Tuplin, A, Evans, David J., Simmonds, P., Diviney, S, Elliott, R.M., Simmonds, P   +22 more
core   +1 more source

Long Non-Coding RNA (lncRNA) Roles in Cell Biology, Neurodevelopment and Neurological Disorders [PDF]

, 2021
Development is a complex process regulated both by genetic and epigenetic and environmental clues. Recently, long non-coding RNAs (lncRNAs) have emerged as key regulators of gene expression in several tissues including the brain.
Justyna Skonieczna, Cerase, A, Vincenza Aliperti, Skonieczna, J, Andrea Cerase, Aliperti, V   +5 more
core   +1 more source

Human cancer long non-coding RNA transcriptomes. [PDF]

PLoS ONE, 2011
Once thought to be a part of the 'dark matter' of the genome, long non-coding RNAs (lncRNAs) are emerging as an integral functional component of the mammalian transcriptome.
Ewan A Gibb, Emily A Vucic, Katey S S Enfield, Greg L Stewart, Kim M Lonergan, Jennifer Y Kennett, Daiana D Becker-Santos, Calum E MacAulay, Stephen Lam, Carolyn J Brown, Wan L Lam   +10 more
doaj   +1 more source

Role of Non-Coding RNAs in Colorectal Cancer: Focus on Long Non-Coding RNAs

International Journal of Molecular Sciences, 2022
Colorectal cancer is one of the most common causes of cancer-related deaths worldwide. Despite the advances in the knowledge of pathogenetic molecular mechanisms and the implementation of more effective drug treatments in recent years, the overall survival rate of patients remains unsatisfactory.
Lulli, Matteo, Napoli, Cristina, Landini, Ida, Mini, Enrico, Lapucci, Andrea   +4 more
openaire   +3 more sources

The Role of Long Non-Coding RNAs in Endometriosis [PDF]

International Journal of Molecular Sciences, 2021
Endometriosis is a chronic gynecological disorder affecting the quality of life and fertility of many women around the world. Heterogeneous and non-specific symptoms may lead to a delay in diagnosis, with treatment options limited to surgery and hormonal therapy.
Quanah J. Hudson, Katharina Proestling, Alexandra Perricos, Lorenz Kuessel, Heinrich Husslein, René Wenzl, Iveta Yotova   +6 more
openaire   +2 more sources