Results 1 to 10 of about 156,390 (266)

LNCcation: lncRNA localization and function

Journal of Cell Biology, 2021
Bridges et al. discuss current knowledge, lingering questions, and emerging themes surrounding lncRNA subcellular localization and its impact on cellular functions.
M. Bridges, Amanda C. Daulagala, A. Kourtidis   +2 more
semanticscholar   +1 more source

Machine learning-based integration develops an immune-derived lncRNA signature for improving outcomes in colorectal cancer

Nature Communications, 2022
Long noncoding RNAs (lncRNAs) are recently implicated in modifying immunology in colorectal cancer (CRC). Nevertheless, the clinical significance of immune-related lncRNAs remains largely unexplored.
Zaoqu Liu, Long Liu, Siyuan Weng, Chunguang Guo, Q. Dang, Hui-Xian Xu, Libo Wang, Taoyuan Lu, Yuyuan Zhang, Zhenqiang Sun, Xinwei Han   +10 more
semanticscholar   +1 more source

Integrated LncRNA Function Upon Genomic and Epigenomic Regulation

Molecules and Cells, 2022
Summary Although some long noncoding (lnc)RNAs are known since the 1950s, the past 25 years have uncovered myriad lncRNAs with diverse sequences, structures, and functions.
Allison B Herman, Dimitrios Tsitsipatis, M. Gorospe   +2 more
semanticscholar   +1 more source

LncRNA-mediated DNA methylation: an emerging mechanism in cancer and beyond

Journal of experimental & clinical cancer research : CR, 2022
DNA methylation is one of the most important epigenetic mechanisms to regulate gene expression, which is highly dynamic during development and specifically maintained in somatic cells.
Wanxu Huang, Hua Li, Qingsong Yu, Wei Xiao, D. Wang   +4 more
semanticscholar   +1 more source

LncRNA

, 2023
 There is growing evidence that long non-coding RNAs (lncRNAs) are significant contributors to the epigenetic mechanisms implicated in the emergence, progression and metastasis of the colorectal cancer (CRC), but many remain underexplored. A novel lncRNA
Ting Zhan (8701923)
core   +1 more source

A novel Cuproptosis-related LncRNA signature to predict prognosis in hepatocellular carcinoma

Scientific Reports, 2022
Increased intracellular toxicity due to an imbalance in copper homeostasis caused by copper ion accumulation could regulate the rate of cancer cell growth and proliferation.
Genhao Zhang, Jianping Sun, Xianwei Zhang   +2 more
semanticscholar   +1 more source

Biological Function of Long Non-coding RNA (LncRNA) Xist

Frontiers in Cell and Developmental Biology, 2021
Long non-coding RNAs (lncRNAs) regulate gene expression in a variety of ways at epigenetic, chromatin remodeling, transcriptional, and translational levels. Accumulating evidence suggests that lncRNA X-inactive specific transcript (lncRNA Xist) serves as
Wenlun Wang, Lu Min, Xinyuan Qiu, Xiaomin Wu, Chuanyang Liu, Jiaxin Ma, Dongyi Zhang, Lingyun Zhu   +7 more
semanticscholar   +1 more source

Emerging role of tumor-related functional peptides encoded by lncRNA and circRNA

Molecular Cancer, 2020
Non-coding RNAs do not encode proteins and regulate various oncological processes. They are also important potential cancer diagnostic and prognostic biomarkers.
Pan Wu, Yongzhen Mo, M. Peng, T. Tang, Y. Zhong, Xiangying Deng, F. Xiong, Can Guo, Xu Wu, Yong Li, Xiaoling Li, Gui-yuan Li, Zhaoyang Zeng, W. Xiong   +13 more
semanticscholar   +1 more source

LncRNA HEPFAL accelerates ferroptosis in hepatocellular carcinoma by regulating SLC7A11 ubiquitination

Cell Death and Disease, 2022
Ferroptosis is a new type of cell death that has been recognized in recent years and is different from apoptosis, autophagy, and necrosis. It is mainly due to cellular iron homeostasis and lipid peroxidation of iron metabolism caused by large ...
Baofu Zhang, Wenming Bao, Sina Zhang, Bo Chen, Xiang Zhou, Jungang Zhao, Zhehao Shi, Tan Zhang, Ziyan Chen, Luhui Wang, Xiangtao Zheng, Gang Chen, Yi Wang   +12 more
semanticscholar   +1 more source

Chapter4_Resis_and_Suscep_DE-lncRNA-DEmRNA-PPI network_and BiNGO_results

, 2023
Chapter4_Resis_and_Suscep_DE-lncRNA-DEmRNA-PPI network_and ...
Aiswarya Jayaprakash (13828057)
core   +1 more source