Results 11 to 20 of about 123,652 (218)
Cancers, 2021 Non-coding RNAs (ncRNAs) have been considered as unimportant additions to the transcriptome. Yet, in light of numerous studies, it has become clear that ncRNAs play important roles in development, health and disease. Long-ignored, long non-coding RNAs (lncRNAs), ncRNAs made of more than 200 nucleotides have gained attention due to their involvement as ...
Lidia Borkiewicz +4 more
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Vitamin D Reduces the Helper T Cells 17 (Th17) Differentiation in Patients with Ulcerative Colitis by Targeting Long Non-coding RNA (lncRNA) OIP5-AS1/miR-26a-5p/IL-6 Axis [PDF]
Iranian Journal of Immunology, 2022 Background: Vitamin D has anti-inflammatory efficacy against ulcerative colitis (UC), however, the mechanism is yet little understood. Objective: To investigate the immunomodulatory effects of vitamin D against the UC, and to explore the potential ...
Chaohui Zhu +5 more
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The Role of LncRNAs in Translation [PDF]
Non-Coding RNA, 2021 Long non-coding RNAs (lncRNAs), a group of non-protein coding RNAs with lengths of more than 200 nucleotides, exert their effects by binding to DNA, mRNA, microRNA, and proteins and regulate gene expression at the transcriptional, post-transcriptional, translational, and post-translational levels. Depending on cellular location, lncRNAs are involved in
Didem Karakas, Bulent Ozpolat
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Long non-coding RNA Panel on Prognosis of Glioma in Iranian Patients
Asian Pacific Journal of Cancer Biology, 2023 Objective: Glioma is one of the most malignant brain tumors, accounting for about half of the gliomas that occur in central nervous system (CNS), originates from the glial tissue of the brain.
Sara Esmaeili +7 more
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E2F1-induced lncRNA, EMSLR regulates lncRNA LncPRESS1 [PDF]
Scientific Reports, 2022 AbstractE2F1 induces hundreds of protein-coding genes influencing diverse signaling pathways but much less is known about its non-coding RNA targets. For identifying E2F1-dependent oncogenic long non-coding RNAs (lncRNAs), we carried out genome-wide transcriptome analysis and discovered an lncRNA, EMSLR, which is induced both in lung adenocarcinoma ...
Priyanka Priyanka +3 more
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Role of 8-autophagy-related long non-coding RNAs signature in prognosis for bladder cancer
Di-san junyi daxue xuebao, 2021 Objective To explore the potential prognostic role and value of autophagy-related lncRNA risk prediction signature in patients with bladder cancer.
TONG Hang +7 more
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The role of lncRNAs and exosomal lncRNAs in cancer metastasis
Biomedicine & Pharmacotherapy, 2023 Tumor metastasis is the main reason for cancer-related death, but there is still a lack of effective therapeutic to inhibit tumor metastasis. Therefore, the discovery and study of new tumor metastasis regulators is a prominent measure for cancer diagnosis and treatment. Long non-coding RNA (lncRNA) is a type of non-coding RNAs over 200 bp in length. It
Yutong, Zhang +10 more
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Advanced Biomedical Research, 2023 Background: Long non-coding RNAs (lncRNAs) have emerged as crucial regulators in various biological processes, including cancer development and progression.
Raha Nikanfar +6 more
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The lncRNA Toolkit: Databases and In Silico Tools for lncRNA Analysis [PDF]
Non-Coding RNA, 2020 Long non-coding RNAs (lncRNAs) are a rapidly expanding field of research, with many new transcripts identified each year. However, only a small subset of lncRNAs has been characterized functionally thus far. To aid investigating the mechanisms of action by which new lncRNAs act, bioinformatic tools and databases are invaluable.
Holly R. Pinkney +2 more
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Identification of a lncRNA/circRNA-miRNA-mRNA ceRNA Network in Alzheimer's Disease
Journal of Integrative Neuroscience, 2023 Background: Alzheimer’s disease (AD) occurs in the elderly and pre-elderly, characterized by decline of memory, cognitive dysfunction, impairment of learning capacity, and motor dysfunction.
Lining Su +3 more
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