Results 41 to 50 of about 123,652 (218)
The lncRNA Pnky in the Brain [PDF]
Cell Stem Cell, 2015 Long noncoding RNAs (lncRNAs) influence diverse cellular processes and have been implicated in regulating stem cell properties. Now in Cell Stem Cell, Ramos et al. (2015) demonstrate that the neural-specific lncRNA Pnky regulates neuronal differentiation from neural stem cells and mediates RNA splicing through interactions with polypyrimidine tract ...
Cho, Kyung-Ok, Hsieh, Jenny
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, 2021 A method based on feature subset recombination and ensemble learning is proposed for identifying lncRNA-encoded short peptides. Sequence composition and physicochemical properties are extracted and fused to be applied to characterize lncRNA-encoded short
JUN MENG (6620789) +2 more
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Oncotarget, 2015 Long non-coding RNAs (lncRNAs) play key roles in diverse biological processes. Moreover, the development and progression of cancer often involves the combined actions of several lncRNAs. Here we propose a multi-step method for constructing lncRNA-lncRNA functional synergistic networks (LFSNs) through co-regulation of functional modules having three ...
Yongsheng, Li +7 more
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The Role of LncRNAs in Uveal Melanoma [PDF]
Cancers, 2021 Uveal melanoma (UM) is an intraocular cancer tumor with high metastatic risk. It is considered a rare disease, but 90% of affected patients die within 15 years. Non-coding elements (ncRNAs) such as long non-coding RNAs (lncRNAs) have a crucial role in cellular homeostasis maintenance, taking part in many critical cellular pathways.
Paula Milán-Rois +3 more
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The pan-cancer lncRNA MILIP links c-Myc to p53 repression
Molecular & Cellular Oncology, 2021 We have recently identified the MYC proto-oncogene, bHLH transcription factor (MYC, best known as c-Myc)-responsive pan-cancer lncRNA c-Myc-Inducible Long noncoding RNA Inactivating P53 (MILIP) as an oncogenic driver.
Yu Chen Feng +5 more
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Stem Cells International, 2016 Noncoding RNAs are critical regulatory factors in essentially all forms of life. Stem cells occupy a special position in cell biology and Biomedicine, and emerging results show that multiple ncRNAs play essential roles in stem cells. We discuss some of the known ncRNAs in stem cells such as embryonic stem cells, induced pluripotent stem cells ...
Shanshan Hu, Ge Shan
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Epithelial-mesenchymal transition-related genes in coronary artery disease
Open Medicine, 2022 Epithelial-mesenchymal transition (EMT) is critical in the development of coronary artery disease (CAD). However, landscapes of EMT-related genes have not been fully established in CAD.
Xu Xiang +4 more
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, 2022 Triple negative breast cancer (TNBC) represents a diverse group of cancers based on their gene expression profiles. While the current mRNA-based classification of TNBC has contributed to our understanding of the heterogeneity of this disease, whether ...
Elango, Ramesh +8 more
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Is Evolutionary Conservation a Useful Predictor for Cancer Long Noncoding RNAs? Insights from the Cancer LncRNA Census 3 [PDF]
, 2022 Evolutionary conservation is a measure of gene functionality that is widely used to prioritise long noncoding RNAs (lncRNA) in cancer research. Intriguingly, while updating our Cancer LncRNA Census (CLC), we observed an inverse relationship between year ...
Vancura, Adrienne +15 more
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LncRNA, miRNA and lncRNA-miRNA interaction in viral infection
Virus Research, 2018 Noncoding RNAs (ncRNAs) are key components of the transcriptome and play an important role in both normal biological activity and pathological processes such as viral infection and tumorigenesis. LncRNAs and miRNAs are the most important elements of ncRNAs and function as vital regulatory elements.
Linlin, Chen, Yan, Zhou, Hongjun, Li
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