Results 41 to 50 of about 144,315 (291)
LncRNAs in ocular neovascularizations
International Journal of Ophthalmology, 2019 The prevalence of eye diseases worldwide is dramatically increasing and represents a major concern in underdeveloped and developed regions. Ocular diseases, previously associated with a higher depression risk, also impose a substantial economic burden on affected families, thus early detection and/or accurate treatment in order to avoid and prevent ...
Yacouba Cissé, Lang Bai, Min-Ting Chen
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The role of lncRNAs and exosomal lncRNAs in cancer metastasis
Biomedicine & Pharmacotherapy, 2023 Tumor metastasis is the main reason for cancer-related death, but there is still a lack of effective therapeutic to inhibit tumor metastasis. Therefore, the discovery and study of new tumor metastasis regulators is a prominent measure for cancer diagnosis and treatment. Long non-coding RNA (lncRNA) is a type of non-coding RNAs over 200 bp in length. It
Yutong, Zhang +10 more
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Long Non-Coding RNAs: New Players in Hematopoiesis and Leukemia [PDF]
, 2015 Long non-coding RNAs (lncRNAs) are important regulators of gene expression that influence almost every step in the life cycle of genes, from transcription to mRNA splicing, RNA decay, and translation.
Ballarino, Monica +2 more
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Shining a Spotlight on RNA m6A Modifications and Potential Targeted Immunotherapy in Ovarian Cancer
Clinical and Experimental Obstetrics & GynecologyObjective: Ovarian cancer is one of the major gynecologic malignancies worldwide. Evidence indicates that N6-methyladenosine (m6A) modification is strongly related to cancer immunity.
Huaqin Pang +3 more
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Neuropsychiatric Disease and Treatment, 2023 Peng Liang, Yingjie Sun, Yue Li, Yundan Liang Department of Pathology and Pathophysiology, School of Basic Medical Sciences, Chengdu Medical College, Chengdu, People’s Republic of ChinaCorrespondence: Yundan Liang, Department of Pathology and ...
Liang P, Sun Y, Li Y, Liang Y
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Noncoder : a web interface for exon array-based detection of long non-coding RNAs [PDF]
, 2012 Due to recent technical developments, a high number of long non-coding RNAs (lncRNAs) have been discovered in mammals. Although it has been shown that lncRNAs are regulated differently among tissues and disease statuses, functions of these transcripts ...
Braun, Thomas +3 more
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Regulation of lncRNA expression
Cellular and Molecular Biology Letters, 2014 AbstractLong non-coding RNAs (lncRNAs) are series of transcripts with important biological functions. Various diseases have been associated with aberrant expression of lncRNAs and the related dysregulation of mRNAs. In this review, we highlight the mechanisms of dynamic lncRNA expression.
Wu, Zhuomin +7 more
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The lncRNA Toolkit: Databases and In Silico Tools for lncRNA Analysis [PDF]
Non-Coding RNA, 2020 Long non-coding RNAs (lncRNAs) are a rapidly expanding field of research, with many new transcripts identified each year. However, only a small subset of lncRNAs has been characterized functionally thus far. To aid investigating the mechanisms of action by which new lncRNAs act, bioinformatic tools and databases are invaluable.
Holly R. Pinkney +2 more
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Two lncRNAs of Chinese cabbage confer Arabidopsis with heat and drought tolerance
Vegetable ResearchCurrently, frequent occurrences of abnormal weather events, including drought and extreme temperatures, are impacting plant growth and crop yields globally.
Yujie Wang +4 more
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Non-coding RNAs participate in the regulatory network of CLDN4 via ceRNA mediated miRNA evasion [PDF]
, 2017 Thousands of genes have been well demonstrated to play important roles in cancer progression. As genes do not function in isolation, they can be grouped into “networks” based on their interactions.
Chen, Xiao-wan +9 more
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