Results 51 to 60 of about 90,265 (219)

Antiviral Therapy-Induced Changes in Long Non-Coding RNA Expression Profiles in Umbilical Cord Blood and Placental Tissues of Hepatitis B Virus-Infected Pregnant Women

International Journal of Women's Health
Cuimin Wang,1,2 Yuting Huang,3 Lanfeng Li,2 Xizhen Huang,2 Yin Huang,2 Xiang Fang,2 Yu Long1,4 1Department of Obstetrics & Gynecology, The First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi Zhuang Autonomous Region, People’s ...
Wang C, Huang Y, Li L, Huang X, Huang Y, Fang X, Long Y   +6 more
doaj  

Long non-coding RNA metallothionein 1 pseudogene 3 promotes p2y12 expression by sponging miR-126 to activate platelet in diabetic animal model

Platelets, 2019
Platelet hyperaggregation and hypercoagulation are associated with increase of thrombogenic risk, especially in patients with type 2 diabetes (T2D).
Ming Zhou, Meng Gao, Yanwei Luo, Rong Gui, Hongwen Ji   +4 more
doaj   +1 more source

Long Noncoding RNA H19 Mediates STAT3‐Dependent Activation of Keratinocytes and Fibroblasts in Systemic Sclerosis Skin

Arthritis &Rheumatology, EarlyView.
Objective Dermal systemic sclerosis (SSc) fibroblasts and their exosomes can activate keratinocytes in SSc, with long noncoding RNA (lncRNA) H19 highlighted as the most up‐regulated RNA in their cargo compared with healthy controls (HCs). The role of H19 in SSc pathogenesis has never been investigated.
Begoña Caballero‐Ruiz, Christopher W. Wasson, Rebecca L. Ross, Francesco Del Galdo   +3 more
wiley   +1 more source

An epigenomic approach to identifying differential overlapping and cis-acting lncRNAs in cisplatin-resistant cancer cells

Epigenetics, 2018
Long noncoding RNAs (lncRNAs) are critical regulators of cell biology whose alteration can lead to the development of diseases such as cancer. The potential role of lncRNAs and their epigenetic regulation in response to platinum treatment are largely ...
Olga Vera, Carlos Rodriguez-Antolin, Javier de Castro, Florian A. Karreth, Thomas A. Sellers, Inmaculada Ibanez de Caceres   +5 more
doaj   +1 more source

Orchestrating the metastatic symphony: the role of extracellular vesicles in the epithelial–mesenchymal transition and pulmonary niche formation of breast cancer

Biological Reviews, EarlyView.
ABSTRACT The complexity of breast cancer (BC) lung metastasis lies in the capacity of tumour cells to interact efficiently with distant organs to promote colonisation, a process that involves the sophisticated coordination of inherent cellular plasticity and the remodelling of the distant microenvironment.
Jian Lu, Reza Shirazi Nia, Junjie Sun, Chrysa Filippopoulou, Daniel De Vega, Pengtao Hu, Heng Liang, Hang Yao, Chaoyue Pan, Xiaoyan Wu, Xidong Gu, Xiaohong Xie, Georgios Giamas   +12 more
wiley   +1 more source

Long noncoding RNA expression in the cervix mid-pregnancy is associated with the length of gestation at delivery

Epigenetics, 2018
Infants born preterm are at increased risk of multiple morbidities and mortality. Why some women deliver preterm remains poorly understood. Prior studies have shown that cervical microRNA expression and DNA methylation are associated with the length of ...
Heather H. Burris, Allan C. Just, Miriam J. Haviland, Dayna T. Neo, Andrea A. Baccarelli, Alexandra E. Dereix, Kasey J. Brennan, Rodosthenis S. Rodosthenous, Steven J. Ralston, Jonathan L. Hecht, Michele R. Hacker   +10 more
doaj   +1 more source

Oocyte–cumulus cell interaction: a key factor in early embryo development

Biological Reviews, EarlyView.
ABSTRACT The evaluation of oocyte competence is a fundamental step in achieving successful outcomes following assisted reproduction techniques (ART). At present, however, conventional oocyte maturation assessment is carried out by morphological observation, which is a subjective method that does not consider molecular features.
Marc Torres‐Garrido, Marc Yeste, Yentel Mateo‐Otero   +2 more
wiley   +1 more source

Evaluation of Serum Exosomal lncRNAs as Diagnostic and Prognostic Biomarkers for Esophageal Squamous Cell Carcinoma

Cancer Management and Research, 2020
Suzhen Yan,1,* Lutao Du,1,* Xiumei Jiang,2 Weili Duan,1 Juan Li,1 Yujiao Xie,1 Yao Zhan,1 Shujun Zhang,1 Lili Wang,2 Shuhai Li,3 Chuanxin Wang1,4 1Department of Clinical Laboratory, The Second Hospital of Shandong University, Jinan, Shandong Province ...
Yan S, Du L, Jiang X, Duan W, Li J, Xie Y, Zhan Y, Zhang S, Wang L, Li S, Wang C   +10 more
doaj  

The Regulatory Roles of Long-non-Coding RNAs in Chemotherapy-Resistant Metastatic Breast Cancer [PDF]

Journal of Advanced Biomedical Sciences, 2020
Currently, breast cancer is the most prevalent malignancy worldwide, with the largest prevalence and mortality among women. The invasion and metastasis are the main causes of death from malignancies. However, the main mechanism of invasion and metastasis
Saeid Ghorbian, Arezo Zaree, Elnaz Khojasteh   +2 more
doaj  

A WGCNA‐Based Approach to Identify Hub Genes Associated With TNM Staging in Urothelial Bladder Carcinoma

Cancer Nexus, EarlyView.
ABSTRACT In this study, we identified gene modules and representative candidate biomarkers linked to clinical progression in patients with UBC. Weighted gene co‐expression network analysis (WGCNA) was used to identify gene modules associated with TNM staging in UBC patients.
Arshia Azmoudeh
wiley   +1 more source