Results 21 to 30 of about 156,390 (266)

LncRNA-mediated regulation of cell signaling in cancer

Oncogene, 2017
To date, a large number of long non-coding RNAs (lncRNAs) have been recently discovered through functional genomics studies. Importantly, lncRNAs have been shown, in many cases, to function as master regulators for gene expression and thus, they can play
Wan-Xin Peng, Pratirodh Koirala, Y. Mo
semanticscholar   +1 more source

Construction of the seven-lncRNA-based prognostic model from ceRNA network to predict resistance to cancer drugs.

, 2021
(A) Risk score distribution in patients with NSCLC, survival status in different groups, and heatmap of the expression of seven lncRNAs. (B) K–M plot represents that patients in the high-risk group had significantly shorter OS than those in the low-risk ...
Jie-Tao Lin (9377048), Wei Guo (86150), Ling-Ling Sun (443325), Hong-Xing Yang (11785983), Cai-Zhi Yang (11785977), Zhong-Yu Huang (11785980), Xi Xiao (623637), Shan Liu (193759), Li Deng (442821), Li-Zhu Lin (9377066), Lei-Hao Hu (11424073)   +10 more
core   +1 more source

Construction of a Ferroptosis-Related Nine-lncRNA Signature for Predicting Prognosis and Immune Response in Hepatocellular Carcinoma

Frontiers in Immunology, 2021
Ferroptosis is an iron-dependent cell death process that plays important regulatory roles in the occurrence and development of cancers, including hepatocellular carcinoma (HCC).
Zhijie Xu, Bi Peng, Qiu-Chun Liang, Xi Chen, Yuan Cai, Shuangshuang Zeng, Kewa Gao, Xiang Wang, Qiao-Yan Yi, Z. Gong, Yuanliang Yan   +10 more
semanticscholar   +1 more source

DataSheet_1_Identification and Validation of a Novel Six-lncRNA-Based Prognostic Model for Lung Adenocarcinoma.pdf

, 2022
ObjectiveThis study was conducted in order to establish a long non-coding RNA (lncRNA)-based model for predicting overall survival (OS) in patients with lung adenocarcinoma (LUAD).MethodsOriginal RNA-seq data of LUAD samples were extracted from The ...
Jingnan Zhang (1793296), Yongfang Wang (3845413), Yuan Wu (299363), Huan Xu (38476), Long Zhang (315279), Xinjie Zheng (11953031), Kai Wang (21246), Lingge Yang (11464957), Weiyu Chen (2216251)   +8 more
core   +1 more source

LncRNA BCRT1 promotes breast cancer progression by targeting miR-1303/PTBP3 axis

Molecular Cancer, 2020
Long noncoding RNAs (lncRNAs) play crucial roles in tumor progression and are aberrantly expressed in various cancers. However, the functional roles of lncRNAs in breast cancer remain largely unknown.
Yiran Liang, Xiaojing Song, Yaming Li, Bing Chen, Wenjing Zhao, Lijuan Wang, Hanwen Zhang, Y. Liu, Dianwen Han, Ning Zhang, T. Ma, Yajie Wang, F. Ye, Dan Luo, Xiaoyan Li, Qifeng Yang   +15 more
semanticscholar   +1 more source

LIMIT is an immunogenic lncRNA in cancer immunity and immunotherapy

Nature Cell Biology, 2021
Major histocompatibility complex-I (MHC-I) presents tumour antigens to CD8+ T cells and triggers anti-tumour immunity. Humans may have 30,000–60,000 long noncoding RNAs (lncRNAs).
Gaopeng Li, Ilona Kryczek, Jutaek Nam, Xiong Li, Shasha Li, Jing Li, Shuang Wei, Sara Grove, Linda Vatan, Jiajia Zhou, W. Du, Heng Lin, Ton Wang, C. Subramanian, J. Moon, M. Cieslik, Mark S. Cohen, W. Zou   +17 more
semanticscholar   +1 more source

LncRNA-Based Classification of Triple Negative Breast Cancer Revealed Inherent Tumor Heterogeneity and Vulnerabilities

, 2022
Triple negative breast cancer (TNBC) represents a diverse group of cancers based on their gene expression profiles. While the current mRNA-based classification of TNBC has contributed to our understanding of the heterogeneity of this disease, whether ...
Elango, Ramesh, Ramesh Elango (7542068), Radhakrishnan Vishnubalaji (3563306), Vishnubalaji, Radhakrishnan, Radhakrishnan Vishnubalaji, Alajez, Nehad M., Nehad M. Alajez, Nehad M. Alajez (7397276), Ramesh Elango   +8 more
core   +1 more source

Lnc2Cancer 3.0: an updated resource for experimentally supported lncRNA/circRNA cancer associations and web tools based on RNA-seq and scRNA-seq data

Nucleic Acids Res., 2020
An updated Lnc2Cancer 3.0 (http://www.bio-bigdata.net/lnc2cancer or http://bio-bigdata.hrbmu.edu.cn/lnc2cancer) database, which includes comprehensive data on experimentally supported long non-coding RNAs (lncRNAs) and circular RNAs (circRNAs) associated
Yue Gao, Shipeng Shang, Shuang Guo, Xin Li, Hanxiao Zhou, Hongjia Liu, Yue Sun, Junwei Wang, Peng Wang, Hui Zhi, Xia Li, Shangwei Ning, Yunpeng Zhang   +12 more
semanticscholar   +1 more source

LncRNA-miRNA axes in breast cancer: Novel points of interaction for strategic attack.

Cancer Letters, 2021
Therapeutic effectiveness in breast cancer can be limited by the underlying mechanisms of pathogenesis, including epithelial-mesenchymal transition (EMT), cancer stem cells (CSCs) and drug resistance. Long non-coding RNAs (lncRNAs) and microRNAs (miRNAs)
J. Venkatesh, M. Wasson, Justin M. Brown, Wasundara Fernando, P. Marcato   +4 more
semanticscholar   +1 more source

TableE13-Pseudo-bulk-of-scRNA-seq-EMT-differential-lncRNA-expression-list.xlsx

, 2022
TableE13-Pseudo-bulk-of-scRNA-seq-EMT-differential-lncRNA-expression-list ...
Adam Williams (12021065), Adam Williams (5459639)   +1 more
core   +1 more source