Results 51 to 60 of about 17,485,262 (316)
Long Non-Coding RNA Function in CD4+ T Cells: What We Know and What Next? [PDF]
, 2019 The non-coding genome has previously been regarded as "junk" DNA; however, emerging evidence suggests that the non-coding genome accounts for some of the greater biological complexity observed in mammals.
Lagos, Dimitris +5 more
core +1 more source
, 2020 Although mammals possess roughly the same number of protein-coding genes as worms, it is evident that the non-coding transcriptome content has become far broader and more sophisticated during evolution.
Paola Briata, Roberto Gherzi
core +1 more source
Non-coding RNAs and glioblastoma: Insight into their roles in metastasis
Molecular Therapy: Oncolytics, 2022 Glioma, also known as glioblastoma multiforme (GBM), is the most prevalent and most lethal primary brain tumor in adults. Gliomas are highly invasive tumors with the highest death rate among all primary brain malignancies.
Seyed Mojtaba Mousavi +10 more
doaj +1 more source
Long non-coding RNAs in osteosarcoma
Oncotarget, 2017 Long non-coding RNAs (lncRNAs) with more than 200 nuleotides, have been explored to participate in various cancer types including osteosarcoma (OS), which is the most common kind of primary bone tumors with high morbidity in infants and adolescents.
Chen, Ruiling +4 more
openaire +3 more sources
Long non‐coding small nucleolar RNA host genes in digestive cancers
Cancer Medicine, 2019 Although long noncoding RNAs (lncRNAs) do not have protein coding capacities, they are involved in the pathogenesis of many types of cancers, including hepatocellular carcinoma, cervical cancer, and gastric cancer. Notably, the roles of lncRNAs are vital
Huan Yang +6 more
doaj +1 more source
Therapeutic role of long non-coding RNA TCONS_00019174 in depressive disorders is dependent on Wnt/$\beta$-catenin signaling pathway [PDF]
Journal of Integrative Neuroscience, 2018 Chronic stress is one of the major causes that lead to major depressive disorder, which is a prevalent mood disorder worldwide. Many patients with major depressive disorder do not benefit from available medication due to the complex etiology of the ...
Xinqiang Ni, Yingzhao Liao, Limin Li, Xiaoli Zhang, Zhengzhi Wu
doaj +1 more source
LINC00473 as an Immediate Early Gene under the Control of the EGR1 Transcription Factor
, 2020 Immediate early genes play an essential role in cellular responses to different stimuli. Many of them are transcription factors that regulate the secondary response gene expression. Non-coding RNAs may also be involved in this regulatory cascade. In fact,
Emilia Vitale +3 more
core +1 more source
Long Non-Coding RNA Modulation of VEGF-A during Hypoxia
, 2018 The role and function of long non-coding RNAs (lncRNAs) in modulating gene expression is becoming apparent. Vascular endothelial growth factor A (VEGF-A) is a key regulator of blood vessel formation and maintenance making it a promising therapeutic ...
Zhen Chen +13 more
core +1 more source
Review: Long non-coding RNA in livestock
Animal, 2020 Less than 2% of mammalian genomes code for proteins, but ‘the majority of its bases can be found in primary transcripts’ – a phenomenon termed the pervasive transcription, which was first reported in 2007.
B. Kosinska-Selbi +2 more
doaj +1 more source
RNA-Mediated Regulation of Meiosis in Budding Yeast
, 2022 Cells change their physiological state in response to environmental cues. In the absence of nutrients, unicellular fungi such as budding yeast exit mitotic proliferation and enter the meiotic cycle, leading to the production of haploid cells that are ...
Vidya Vardhini Pondugala +3 more
core +1 more source