Results 1 to 10 of about 160,128 (263)
Circular RNA HIPK3: A Key Circular RNA in a Variety of Human Cancers [PDF]
Frontiers in Oncology, 2020 Circular RNAs (circRNAs), which act as initiators and promoters of various diseases, were thought to be mostly noncoding RNAs (ncRNAs) in eukaryotes, until recent studies confirmed that some circRNAs have the function of encoding proteins.
Jingyuan Wen +5 more
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Circular RNA in hepatocellular carcinoma: emerging therapeutic strategies [PDF]
Frontiers in ImmunologyCircular RNAs, or circRNAs, are unique single-stranded RNA molecules that form covalently closed circles. They possess a wide range of cellular functions and can act as tumor suppressors or promoters, regulating various aspects of carcinogenesis.
Gregor Jazbec, Tadeja Režen
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Expression Significance of Serum Circular RNA CDYL and Circular RNA ROBO2 in Patients with Acute Myocardial Infarction and the Value of Their Combined Prediction for Major Adverse Cardiovascular Events [PDF]
International Journal of General MedicineFang Wang, Rui Liu, Cuirong Zhang, Shenglin Liu Department of Cardiology, Shanghai East Hospital, School of Medicine, Tongji University, Shanghai, 200120, People’s Republic of ChinaCorrespondence: Shenglin Liu, Email isl0076@163.comObjective: To ...
Wang F, Liu R, Zhang C, Liu S
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Circular RNA—Is the Circle Perfect?
Biomolecules, 2021 Circular RNA (circRNA) is a distinct class of non-coding RNA produced, in principle, using a back-splicing mechanism, conserved during evolution, with increased stability and a tissue-dependent expression.
Lavinia Caba +4 more
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Cell-type specific features of circular RNA expression. [PDF]
PLoS Genetics, 2013 Thousands of loci in the human and mouse genomes give rise to circular RNA transcripts; at many of these loci, the predominant RNA isoform is a circle. Using an improved computational approach for circular RNA identification, we found widespread circular
Julia Salzman +4 more
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Circular RNAs in Toxicology [PDF]
Toxicological Sciences, 2020 Abstract Circular RNAs (circRNAs) are a type of closed, long, non-coding RNAs, which have attracted significant attention in recent years. CircRNAs exhibit unique functions and are characterized by stable expression in various tissues across different species.
Yueting Shao, Yiguo Jiang
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Molecular Therapy - Nucleic Acids, 2019 Circular RNAs (circRNAs) are a class of single-stranded closed RNA molecules that are formed by precursor mRNA back-splicing or skipping events of thousands of genes in eukaryotes as covalently closed continuous loops. High-throughput sequencing and bioinformatics approaches have uncovered the broad expression of circRNAs across species.
Duc-Hiep Bach +2 more
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Detecting circular RNA from high-throughput sequence data with de Bruijn graph
BMC Genomics, 2020 Background Circular RNA is a type of non-coding RNA, which has a circular structure. Many circular RNAs are stable and contain exons, but are not translated into proteins.
Xin Li, Yufeng Wu
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BMC Cancer, 2022 Background Liver cirrhosis is a well-known risk factor for hepatocellular carcinoma (HCC). However, some HCC cases can also originate from non-cirrhotic livers.
Hongyu Li +6 more
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Nature Communications, 2023 Circular RNAs have been extensively studied in eukaryotes, but their presence and/or biological functionality in bacteria are unclear. Here, we show that a regulatory noncoding RNA (DucS) exists in both linear and circular conformation in Bacillus ...
Ting-Ting He +10 more
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