Results 11 to 20 of about 160,128 (263)
Research progress on regulatory mechanisms of circular RNA nuclear receptor interacting protein 1 in tumor occurrence and development [PDF]
Jichu yixue yu linchuang, 2023 Circular RNA (circRNA) is a class of single-stranded covalently closed non-coding RNA molecules widely expressed in eukaryotic cells. Recent studies have found that circRNA has been involved in modulating biological processes such as cell proliferation ...
GAO Xin, YU Yongbo, WANG Haicun, JIANG Xingming, WANG Zhidong
doaj +1 more source
Circular RNA in tumor metastasis
Molecular Therapy: Nucleic Acids, 2021 Circular RNAs (circRNAs) are a type of endogenous non-coding RNA that were discovered to regulate gene expression through multiple pathways. Metastasis remains one of the biggest obstacles in cancer treatment.
Chao Zhang +9 more
doaj +1 more source
Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms, 2020 Skeletal muscles have an immense ability to regenerate from the muscle stem cells called satellite cells. The process of skeletal muscle regeneration is called myogenesis, which starts with activation of quiescent satellite cells immediately after muscle injury followed by proliferation and fusion of myoblasts into myotubes.
Arundhati, Das +4 more
openaire +3 more sources
Circular RNA: Biosynthesis in vitro
Frontiers in Bioengineering and Biotechnology, 2021 Circular RNA (circRNA) is a unique type of noncoding RNA molecule. Compared with traditional linear RNA, circRNA is a covalently closed circle produced by a process called backsplicing.
Xinjie Chen, Yuan Lu
doaj +1 more source
CIRCULAR RNA – miRNA MEDIATED INTERACTION IN MYOCARDIAL INFARCTION [PDF]
Journal of IMAB, 2021 Circular RNA (circRNAs) belong to the long non-coding RNA family, but unlike the linear RNA in circular RNA, the 3’ and 5’ end in the RNA molecule are joined together, forming their circular structure.
Yordanka Doneva +5 more
doaj +1 more source
In vitro circularization of RNA [PDF]
RNA Biology, 2016 Over the past 2 decades, different types of circular RNAs have been discovered in all kingdoms of life, and apparently, those circular species are more abundant than previously thought. Apart from circRNAs in viroids and viruses, circular transcripts have been discovered in rodents more than 20 y ago and recently have been reported to be abundant in ...
Sabine, Müller, Bettina, Appel
openaire +2 more sources
Circular RNAs—The Road Less Traveled
Frontiers in Molecular Biosciences, 2020 Circular RNAs are the most recent addition in the non-coding RNA family, which has started to gain recognition after a decade of obscurity. The first couple of reports that emerged at the beginning of this decade and the amount of evidence that has ...
Ashirbad Guria +3 more
doaj +1 more source
Research progress of circular RNA zinc finger RNA binding protein in malignant tumors [PDF]
Jichu yixue yu linchuang, 2022 Circular RNA is a kind of RNA molecule with special covalent closed circular structure. The existing research results showed that circular RNA zinc finger RNA binding protein (circRNA-ZFR) was abnormally expressed in many malignant tumors, and its ...
LIU Lang, WANG Hai-cun, GAO Xin, LIU Guang-lin, ZHAO Yu-qiao, JIANG Xing-ming
doaj +1 more source
Frontiers in Immunology, 2022 Circular DNAs derived from single-stranded RNA viruses play important roles in counteracting viral infection. However, whether double-stranded RNA viruses generate functional circular DNAs is still unknown. Using circDNA sequencing, divergent PCR, DNA in
Min Zhu +13 more
doaj +1 more source
Biogenesis of Circular RNAs [PDF]
Cell, 2014 Circular RNAs are generated during splicing through various mechanisms. Ashwal-Fluss et al. demonstrate that exon circularization and linear splicing compete with each other in a tissue-specific fashion, and Zhang et al. show that exon circularization depends on flanking intronic complementary sequences.
Vicens, Quentin, Westhof, Eric
openaire +2 more sources