Results 41 to 50 of about 169,673 (308)

CiLiQuant: Quantification of RNA Junction Reads Based on Their Circular or Linear Transcript Origin

Frontiers in Bioinformatics, 2022
Distinguishing circular RNA reads from reads derived from the linear host transcript is a challenging task because of sequence overlap. We developed a computational approach, CiLiQuant, that determines the relative circular and linear abundance of ...
Annelien Morlion, Annelien Morlion, Eva Hulstaert, Eva Hulstaert, Marieke Vromman, Marieke Vromman, Jasper Anckaert, Jasper Anckaert, Celine Everaert, Celine Everaert, Jo Vandesompele, Jo Vandesompele, Pieter Mestdagh, Pieter Mestdagh   +13 more
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Interior circular RNA [PDF]

RNA Biology, 2019
Formed by back splicing or back fusion of linear RNAs, circular RNAs (circRNAs) constitute a new class of non-coding RNAs of eukaryotes. Recent studies reveal a spliceosome-dependent biogenesis of circRNAs where circRNAs arise at the intron-exon junctions of mRNAs.
Xiaoxin Liu, Zhangfeng Hu, Junfei Zhou, Cheng Tian, Guangmei Tian, Miao He, Lifen Gao, Lihong Chen, Tiantian Li, Hai Peng, Weixiong Zhang   +10 more
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CircRNAs and RNA-Binding Proteins Involved in the Pathogenesis of Cancers or Central Nervous System Disorders

, 2023
Circular RNAs (circRNAs), a newly recognized group of noncoding RNA transcripts, have established widespread attention due to their regulatory role in cell signaling. They are covalently closed noncoding RNAs that form a loop, and are typically generated
1000050242110, Suga Naoko, 菅 尚子, Matsuda Satoru, つじ あい, 辻 愛, Tsuji Ai, 松田 覚, 池田 祐香, Sawamura Haruka, Yoshikawa Sayuri, Ikeda Yuka, すが なおこ, まつだ さとる, Taniguchi Kurumi, いけだ ゆか, Nakashima Moeka, Morikawa Sae   +17 more
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Hfq binding changes the structure of Escherichia coli small noncoding RNAs OxyS and RprA, which are involved in the riboregulation of rpoS [PDF]

, 2013
: OxyS and RprA are two small noncoding RNAs (sRNAs) that modulate the expression of rpoS, encoding an alternative sigma factor that activates transcription of multiple Escherichia coli stress-response genes.
Taylor, James E., Callaghan, Anastasia J., Helen A. Vincent, Phillips, Jack O., Cary, Peter, Vincent, H., Peter D. Cary, Sobott, F., Jack O. Phillips, Frank Sobott, Vincent, Helen A., Henderson, Charlotte A., Stone, Carlanne, Alessandra Casamento, Henderson, Charlotte, Carlanne M. Stone, Anastasia J. Callaghan, Darren M. Gowers, Cary, Peter D., Charlotte A. Henderson, James E.N. Taylor, Casamento, A., Callaghan, Anastasia, Phillips, Jack, Gowers, Darren, Casamento, Alessandra, Stone, Carlanne M., Sobott, Frank, Gowers, Darren M.   +28 more
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Characterizing Expression and Regulation of Gamma-Herpesviral Circular RNAs

Frontiers in Microbiology, 2021
Multiple herpesviruses have been recently found to encode viral circular RNAs. Like cellular circular RNAs, these RNAs lack poly-A tails and their 5′ and 3′ ends have been joined, which confers protection from RNA exonucleases. We examined the expression
Takanobu Tagawa, Daniel Oh, Jerico Santos, Jerico Santos, Sarah Dremel, Guruswamy Mahesh, Thomas S. Uldrick, Robert Yarchoan, Vishal N. Kopardé, Vishal N. Kopardé, Joseph M. Ziegelbauer   +10 more
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Circular RNA Regulation of Myogenesis

Cells, 2019
Circular RNA (circRNA) is a novel class of non-coding RNA generated by pre-mRNA back splicing, which is characterized by a closed-loop structure. Although circRNAs were firstly reported decades ago, their regulatory roles have not been discovered until ...
Pengpeng Zhang, Zhe Chao, Rui Zhang, Ruoqi Ding, Yaling Wang, Wei Wu, Qiu Han, Cencen Li, Haixia Xu, Lei Wang, Yongjie Xu   +10 more
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Cost-Effective Transcriptome-Wide Profiling of Circular RNAs by the Improved-tdMDA-NGS Method

Frontiers in Molecular Biosciences, 2022
Covalently closed circular RNAs are neoteric to the eukaryotic family of long non-coding RNAs emerging as a result of 5′–3′ backsplicing from exonic, intronic, or intergenic regions spanning the parental gene.
Ashirbad Guria, Priyanka Sharma, Nagesh Srikakulam, Akhil Baby, Sankar Natesan, Gopal Pandi   +5 more
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Structural insights into the dynamics and function of the C-terminus of the E. coli RNA chaperone Hfq

, 2011
The hexameric Escherichia coli RNA chaperone Hfq (Hfq(Ec)) is involved in riboregulation of target mRNAs by small trans-encoded RNAs. Hfq proteins of different bacteria comprise an evolutionarily conserved core, whereas the C-terminus is variable in ...
Beich-Frandsen, Mads (Department of Structural and Computational Biology, Centre for Molecular Biology, University of Vienna), Kontaxis, Georg (Department of Structural and Computational Biology, Centre for Molecular Biology, University of Vienna), Blasi, U., Rajkowitsch, L., Miles, Andrew (Birkbeck College), Sjöblom, Björn (Department of Structural and Computational Biology, Centre for Molecular Biology, University of Vienna), Miles, Andrew J., Svergun, D.I., Kloiber, K., Kristina Djinović-Carugo, Vecerek, B., Karin Kloiber, Konarev, P.V., Lukas Rajkowitsch, Hämmerle, Hermann Konrad (Department of Biochemistry and Cell Biology, Centre for Molecular Biology, University of Vienna), Georg Kontaxis, Bläsi, Udo (Department of Microbiology, Immunobiology and Genetics, Centre for Molecular Biology, University of Vienna), Djinovic-Carugo, K., Robert Konrat, Branislav Večerek, Konarev, Peter V. (EMBL Hamburg), Andrew J. Miles, Kloiber, Karin (Department of Structural and Computational Biology, Centre for Molecular Biology, University of Vienna), Rajkowitsch, Lukas (Department of Biochemistry and Cell Biology, Centre for Molecular Biology, University of Vienna), Udo Bläsi, Wallace, Bonnie A., Svergun, D. I., Petr V. Konarev, Svergun, Dimitri I. (EMBL Hamburg), Björn Sjöblom, Hammerle, H., Mads Beich-Frandsen, Wallace, B. A., Sjoblom, B., Miles, A. J., Konrat, Robert (Department of Structural and Computational Biology, Centre for Molecular Biology, University of Vienna), Vecerek, Branislav (Department of Microbiology, Immunobiology and Genetics, Centre for Molecular Biology, University of Vienna), Dimitri I. Svergun, B. A. Wallace, Beich Frandsen, M., Djinovic Carugo, K., Konarev, P. V., Beich-Frandsen, M., Konrat, R., Djinovic-Carugo, Kristina (Department of Structural and Computational Biology, Centre for Molecular Biology, University of Vienna), Hermann Hämmerle, Kontaxis, G.   +46 more
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Differential polyadenylation of ribosomal RNA during post-transcriptional processing in Leishmania. [PDF]

, 2005
The protozoan parasite Leishmania belongs to the most ancient eukaryotic lineages and this is reflected in several distinctive biological features, such as eukaryotic polycistronic transcription and RNA trans-splicing.
Laurent, T., Chappuis, F., Llanos-Cuentas, A., Llanos-Cuentas, A, V. YARDLEY, F. CHAPPUIS, Laurent, T, T. LAURENT, Dujardin, J. C., Vandesompele, J, J.-C. DUJARDIN, DE DONCKER, S, S. RIJAL, Decuypere, S., S. DECUYPERE, Yardley, V, De Donckeri, S, Vandesompele, Jo, Rijal, S., J. AREVALO, Vandesompele, J., S. DE DONCKER, J. VANDESOMPELE, Yardley, V., Chappuis, F, Arevalo, J., Arevalo, J, Rijal, S, De Doncker, S., A. LLANOS-CUENTAS, Dujardin, JC, Decuypere, S   +31 more
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Translation of Circular RNAs

Nucleic Acids Research
Circular RNAs (circRNAs) are covalently closed RNAs that are present in all eukaryotes tested. CircRNAs are less abundantly expressed than mRNAs. Recent RNAseq analyses indicate that more than 800,000 circRNA isoforms exist in humans, which is more than twice the number of currently known mRNA isoforms. CircRNAs are generated through backsplicing that
Giorgi Margvelani, Karol Andrea Arizaca Maquera, Justin Ralph Welden, David W Rodgers, Stefan Stamm   +4 more
openaire   +2 more sources