Results 51 to 60 of about 2,234,197 (338)
Experimental and Molecular Medicine, 2018 Spinal disease: Circular RNA linked to disc degeneration A circular RNA molecule helps protect against degenerative disc disease. Hua Wang and coworkers from Sun Yat-Sen University in Guangzhou, China, examined whether circular RNAs, regulatory molecules
Hua Wang +8 more
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CiLiQuant: Quantification of RNA Junction Reads Based on Their Circular or Linear Transcript Origin
Frontiers in Bioinformatics, 2022 Distinguishing circular RNA reads from reads derived from the linear host transcript is a challenging task because of sequence overlap. We developed a computational approach, CiLiQuant, that determines the relative circular and linear abundance of ...
Annelien Morlion +13 more
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Engineering circular RNA for enhanced protein production
Nature Biotechnology, 2022 Protein expression from circular RNAs is enhanced several hundred-fold by optimizing vector design. Circular RNAs (circRNAs) are stable and prevalent RNAs in eukaryotic cells that arise from back-splicing.
Robert Chen +9 more
semanticscholar +1 more source
Circ-ZNF609 regulates G1-S progression in rhabdomyosarcoma [PDF]
, 2019 Circular RNAs (circRNAs) represent a class of covalently closed RNAs, derived from non-canonical splicing events, which are expressed in all eukaryotes and often conserved among different species.
Bozzoni, Irene +9 more
core +1 more source
Characterizing Expression and Regulation of Gamma-Herpesviral Circular RNAs
Frontiers in Microbiology, 2021 Multiple herpesviruses have been recently found to encode viral circular RNAs. Like cellular circular RNAs, these RNAs lack poly-A tails and their 5′ and 3′ ends have been joined, which confers protection from RNA exonucleases. We examined the expression
Takanobu Tagawa +10 more
doaj +1 more source
Interaction and cross-talk between non-coding RNAs. [PDF]
, 2017 Non-coding RNA (ncRNA) has been shown to regulate diverse cellular processes and functions through controlling gene expression. Long non-coding RNAs (lncRNAs) act as a competing endogenous RNAs (ceRNAs) where microRNAs (miRNAs) and lncRNAs regulate each ...
Dahiya, Rajvir +3 more
core +2 more sources
Circular RNAs and Cardiovascular Regeneration [PDF]
Frontiers in Cardiovascular Medicine, 2021 circular RNAs (circRNAs) are a type of non-coding RNAs that are widely present in eukaryotic cells. They have the characteristics of stable structure, high abundance, and cell or tissue specific expression. circRNAs are single-stranded RNAs that are covalently back spliced to form closed circular loops.
Ling Tang +3 more
openaire +3 more sources
Circular RNA vaccine induces potent T cell responses
Proceedings of the National Academy of Sciences of the United States of America, 2023 Significance Circular RNAs (circRNAs) are a unique class of RNAs that are highly stable compared to linear mRNAs and can be engineered to provide durable protein expression.
Laura Amaya +6 more
semanticscholar +1 more source
Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms, 2020 Skeletal muscles have an immense ability to regenerate from the muscle stem cells called satellite cells. The process of skeletal muscle regeneration is called myogenesis, which starts with activation of quiescent satellite cells immediately after muscle injury followed by proliferation and fusion of myoblasts into myotubes.
Arundhati, Das +4 more
openaire +3 more sources
Circular RNA Regulation of Myogenesis
Cells, 2019 Circular RNA (circRNA) is a novel class of non-coding RNA generated by pre-mRNA back splicing, which is characterized by a closed-loop structure. Although circRNAs were firstly reported decades ago, their regulatory roles have not been discovered until ...
Pengpeng Zhang +10 more
doaj +1 more source