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BMC Cancer, 2022 Background Liver cirrhosis is a well-known risk factor for hepatocellular carcinoma (HCC). However, some HCC cases can also originate from non-cirrhotic livers.
Hongyu Li +6 more
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CIRCULAR RNA – miRNA MEDIATED INTERACTION IN MYOCARDIAL INFARCTION [PDF]
Journal of IMAB, 2021 Circular RNA (circRNAs) belong to the long non-coding RNA family, but unlike the linear RNA in circular RNA, the 3’ and 5’ end in the RNA molecule are joined together, forming their circular structure.
Yordanka Doneva +5 more
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Nature Communications, 2023 Circular RNAs have been extensively studied in eukaryotes, but their presence and/or biological functionality in bacteria are unclear. Here, we show that a regulatory noncoding RNA (DucS) exists in both linear and circular conformation in Bacillus ...
Ting-Ting He +10 more
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Circular RNA in tumor metastasis
Molecular Therapy: Nucleic Acids, 2021 Circular RNAs (circRNAs) are a type of endogenous non-coding RNA that were discovered to regulate gene expression through multiple pathways. Metastasis remains one of the biggest obstacles in cancer treatment.
Chao Zhang +9 more
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Circular RNA: Biosynthesis in vitro
Frontiers in Bioengineering and Biotechnology, 2021 Circular RNA (circRNA) is a unique type of noncoding RNA molecule. Compared with traditional linear RNA, circRNA is a covalently closed circle produced by a process called backsplicing.
Xinjie Chen, Yuan Lu
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Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms, 2020 Skeletal muscles have an immense ability to regenerate from the muscle stem cells called satellite cells. The process of skeletal muscle regeneration is called myogenesis, which starts with activation of quiescent satellite cells immediately after muscle injury followed by proliferation and fusion of myoblasts into myotubes.
Arundhati, Das +4 more
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Circular RNAs—The Road Less Traveled
Frontiers in Molecular Biosciences, 2020 Circular RNAs are the most recent addition in the non-coding RNA family, which has started to gain recognition after a decade of obscurity. The first couple of reports that emerged at the beginning of this decade and the amount of evidence that has ...
Ashirbad Guria +3 more
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Research progress on regulatory mechanisms of circular RNA nuclear receptor interacting protein 1 in tumor occurrence and development [PDF]
Jichu yixue yu linchuang, 2023 Circular RNA (circRNA) is a class of single-stranded covalently closed non-coding RNA molecules widely expressed in eukaryotic cells. Recent studies have found that circRNA has been involved in modulating biological processes such as cell proliferation ...
GAO Xin, YU Yongbo, WANG Haicun, JIANG Xingming, WANG Zhidong
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Biogenesis of Circular RNAs [PDF]
Cell, 2014 Circular RNAs are generated during splicing through various mechanisms. Ashwal-Fluss et al. demonstrate that exon circularization and linear splicing compete with each other in a tissue-specific fashion, and Zhang et al. show that exon circularization depends on flanking intronic complementary sequences.
Vicens, Quentin, Westhof, Eric
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Structural insights into the dynamics and function of the C-terminus of the E. coli RNA chaperone Hfq [PDF]
, 2011 The hexameric Escherichia coli RNA chaperone Hfq (Hfq(Ec)) is involved in riboregulation of target mRNAs by small trans-encoded RNAs. Hfq proteins of different bacteria comprise an evolutionarily conserved core, whereas the C-terminus is variable in ...
Blasi, U. +33 more
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