Results 11 to 20 of about 16,781,272 (315)
Long non‐coding RNA MALAT1 regulates retinal neurodegeneration through CREB signaling
EMBO Molecular Medicine, 2016 The nervous and vascular systems, although functionally different, share many common regulators of function maintenance. Long non‐coding RNAs (lncRNAs) are important players in many biological processes and human disorders.
Jin Yao +15 more
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Long Non-Coding RNAs in Insects [PDF]
Animals, 2021 Only a small subset of all the transcribed RNAs are used as a template for protein translation, whereas RNA molecules that are not translated play a very important role as regulatory non-coding RNAs (ncRNAs). Besides traditionally known RNAs (ribosomal and transfer RNAs), ncRNAs also include small non-coding RNAs (sncRNAs) and long non-coding RNAs ...
Chhavi Choudhary +9 more
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Long Non-Coding RNA Epigenetics [PDF]
International Journal of Molecular Sciences, 2021 Long noncoding RNAs exceeding a length of 200 nucleotides play an important role in ensuring cell functions and proper organism development by interacting with cellular compounds such as miRNA, mRNA, DNA and proteins. However, there is an additional level of lncRNA regulation, called lncRNA epigenetics, in gene expression control.
Marek Kazimierczyk, Jan Wrzesinski
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Frontiers in Microbiology, 2023 Microbiome and their metabolites are increasingly being recognized for their role in colorectal cancer (CRC) carcinogenesis. Towards revealing new CRC biomarkers, we compared 16S rRNA gene sequencing and liquid chromatography-mass spectrometry (LC–MS ...
Jiahui Feng +12 more
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Research progress on subcellular localization and function of long non-coding RNA [PDF]
Jichu yixue yu linchuang, 2023 The subcellular localization of long non-coding RNA(lncRNA) is closely related to its function. When localized in the nucleus, lncRNA can maintain chromatin structure, regulate gene transcription and participate in variable splicing of mRNA.
SU Yue, LIANG Linhui, HE Xianghuo
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Translational Oncology, 2023 Objectives: To investigate the clinical significance of Chloride Intracellular Channel 1 (CLIC1) expression in esophageal squamous cell carcinoma (ESCC) and its functional contribution and molecular mechanisms to the progression of ESCC.
Huiwu Geng +12 more
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Long Non Coding RNA Based Regulation of Cerebrovascular Endothelium
Frontiers in Genetics, 2022 The rapid and high throughput discovery of long non coding RNAs (lncRNAs) has far outstripped the functional annotation of these novel transcripts in their respective cellular contexts.
Samatha Mathew +3 more
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Long non-coding RNAs in oncourology
Non-coding RNA Research, 2021 For several decades, research in tumor biology has focused on the involvement of genes encoding a protein. Only recently has it been discovered that a whole class of molecules called non-coding RNAs (ncRNAs) play a key regulatory role in health and disease. Long noncoding RNAs (lncRNAs) are a group of noncoding RNAs longer than 200 nucleotides.
Ilgiz Gareev +10 more
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Journal of Experimental & Clinical Cancer Research, 2022 Background Distant metastasis is the major cause of clear cell renal cell carcinoma (ccRCC)-associated mortality. However, molecular mechanisms involved in ccRCC metastasis remain to be fully understood.
Yanliang Wang +15 more
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The Involvement of Long Non-Coding RNAs in Bone [PDF]
International Journal of Molecular Sciences, 2021 A harmonious balance between osteoblast and osteoclast activity guarantees optimal bone formation and resorption, pathological conditions affecting the bone may arise. In recent years, emerging evidence has shown that epigenetic mechanisms play an important role during osteoblastogenesis and osteoclastogenesis processes, including long non-coding RNAs (
Aurilia C. +5 more
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