Results 41 to 50 of about 8,401,372 (300)
Long Noncoding RNAs in Plants [PDF]
, 2017 The eukaryotic genomes are pervasively transcribed. In addition to protein-coding RNAs, thousands of long noncoding RNAs (lncRNAs) modulate key molecular and biological processes. Most lncRNAs are found in the nucleus and associate with chromatin, but lncRNAs can function in both nuclear and cytoplasmic compartments.
Hsiao-Lin V, Wang, Julia A, Chekanova
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Long non-coding RNA and diseases [PDF]
Jichu yixue yu linchuangLong non-coding RNA (lncRNA) is a class of endogenous non-coding RNA with a length of more than 200 nt. Due to lack of open reading frame (ORF), they lack the ability to directly encode proteins, but they play a crucial role in gene regulation.
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The Regulatory Activity of Noncoding RNAs in ILCs
Cells, 2021 Innate lymphoid cells (ILCs) are innate lymphocytes playing essential functions in protection against microbial infections and participate in both homeostatic and pathological contexts, including tissue remodeling, cancer, and inflammatory disorders.
Alessio Grimaldi +8 more
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NONCODE v3.0: integrative annotation of long noncoding RNAs [PDF]
Nucleic Acids Research, 2011 Facilitated by the rapid progress of high-throughput sequencing technology, a large number of long noncoding RNAs (lncRNAs) have been identified in mammalian transcriptomes over the past few years. LncRNAs have been shown to play key roles in various biological processes such as imprinting control, circuitry controlling pluripotency and differentiation,
Dechao Bu +14 more
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Review: Long non-coding RNA in livestock
Animal, 2020 Less than 2% of mammalian genomes code for proteins, but ‘the majority of its bases can be found in primary transcripts’ – a phenomenon termed the pervasive transcription, which was first reported in 2007.
B. Kosinska-Selbi +2 more
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Long Noncoding RNA in Hematopoiesis and Immunity [PDF]
Immunity, 2015 Dynamic gene expression during cellular differentiation is tightly coordinated by transcriptional and post-transcriptional mechanisms. An emerging theme is the central role of long noncoding RNAs (lncRNAs) in the regulation of this specificity.
Satpathy, Ansuman T., Chang, Howard Y.
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MALAT1 Long Non-Coding RNA: Functional Implications
Non-Coding RNA, 2020 The mammalian genome is pervasively transcribed and the functional significance of many long non-coding RNA (lncRNA) transcripts are gradually being elucidated.
Gayatri Arun +2 more
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Circular Intronic Long Noncoding RNAs [PDF]
Molecular Cell, 2013 We describe the identification and characterization of circular intronic long noncoding RNAs in human cells, which accumulate owing to a failure in debranching. The formation of such circular intronic RNAs (ciRNAs) can be recapitulated using expression vectors, and their processing depends on a consensus motif containing a 7 nt GU-rich element near the
Zhang, Yang +8 more
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Long Noncoding RNA: Genome Organization and Mechanism of Action
, 2017 For the last four decades, we have known that noncoding RNAs maintain critical housekeeping functions such as transcription, RNA processing, and translation.
Debosree Pal +5 more
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Long Noncoding RNAs in Cardiovascular Disease
Current Opinion in Cardiology, 2019 Purpose of review Here, we review recent findings on the role of long noncoding RNAs (lncRNAs) in cardiovascular disease (CVD). In addition, we highlight some of the latest findings in lncRNA biology, providing an outlook for future avenues of lncRNA research in CVD.
Kohlmaier, Alexander +2 more
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