Results 61 to 70 of about 103,197 (166)

Long noncoding RNA in liver diseases [PDF]

open access: yesHepatology, 2014
The identification of the presence of large RNA transcripts that do not code for proteins but that may have biological functions has provided an important new perspective in gene regulation. These long noncoding RNAs (lncRNAs) are being increasingly recognized to contribute to many biological processes through diverse ...
Kenji, Takahashi   +3 more
openaire   +2 more sources

ZFAS1: a novel tumor-related long non-coding RNA

open access: yesCancer Cell International, 2018
Long non-coding RNAs (lncRNA) are classified as a kind of RNA, which are longer than 200 nucleotides in length and cannot be translated into proteins. Multiple studies have demonstrated that lncRNAs are involved in various cellular processes, including ...
Dan Dong   +3 more
doaj   +1 more source

Long noncoding RNAs in cell biology

open access: yesSeminars in Cell & Developmental Biology, 2011
Whole genome transcriptomic analyses have identified large numbers of dynamically expressed long non-protein-coding RNAs (lncRNAs) in mammals and other animals whose functions are, as yet, largely unknown. Here we summarize the growing evidence that lncRNAs, like mRNAs, can be trafficked to and function in a wide variety of subcellular locations ...
Clark, Michael B., Mattick, John S.
openaire   +6 more sources

Revealing potential long non-coding RNA biomarkers in lung adenocarcinoma using long non-coding RNA-mediated competitive endogenous RNA network

open access: yesBrazilian Journal of Medical and Biological Research
In our study, we aimed to reveal potential long non-coding RNAs (lncRNA) biomarkers in lung adenocarcinoma (LAD) using lncRNA-mediated competing endogenous RNAs (ceRNAs) network (LMCN).
T-G. Zhu   +4 more
doaj   +1 more source

Long noncoding RNAs in biology and hematopoiesis

open access: yesBlood, 2013
Abstract Genome and transcriptome sequencing have revealed a rich assortment of noncoding RNAs in eukaryote cells, including long noncoding RNAs (lncRNAs), which regulate gene expression independent of protein coding potential. LncRNAs modulate protein coding gene expression in many cell types by regulating multiple processes, including ...
Vikram R, Paralkar, Mitchell J, Weiss
openaire   +3 more sources

Identification and function of long non-coding RNA

open access: yesFrontiers in Cellular Neuroscience, 2013
Long non-coding (lnc) RNAs are defined as non-protein coding RNAs distinct from housekeeping RNAs such as tRNAs, rRNAs, and snRNAs, and independent from small RNAs with specific molecular processing machinery such as micro- or piwi-RNAs.
Carl eErnst, Cynthia C Morton
doaj   +1 more source

Advances in the role of noncoding RNA in temporomandibular arthritis

open access: yesKouqiang hemian waike zazhi
Temporomandibular joint osteoarthritis (TMJOA) is a common clinical disease. However, the pathogenesis of TMJOA is still unclear, and there is a lack of effective treatment, bringing great distress to patients.
WU Wenjing, SU Jiansheng
doaj   +1 more source

Noncoding elements in wheat defence response to fusarium head blight

open access: yesScientific Reports
Wheat (Triticum aestivum L.) is a major source of global food security while various stressors, including biotic and abiotic factors, directly affect its production.
Tugdem Muslu   +6 more
doaj   +1 more source

Long non-coding RNA Databases in Cardiovascular Research

open access: yesGenomics, Proteomics & Bioinformatics, 2016
With the rising interest in the regulatory functions of long non-coding RNAs (lncRNAs) in complex human diseases such as cardiovascular diseases, there is an increasing need in public databases offering comprehensive and integrative data for all aspects ...
Frank Rühle, Monika Stoll
doaj   +1 more source

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