Results 51 to 60 of about 103,197 (166)
Long non-coding RNA profiling of pediatric Medulloblastoma
BMC Medical Genomics, 2020 Background Medulloblastoma (MB) is one of the most common malignant cancers in children. MB is primarily classified into four subgroups based on molecular and clinical characteristics as (1) WNT (2) Sonic-hedgehog (SHH) (3) Group 3 (4) Group 4. Molecular
Varun Kesherwani +5 more
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PVT1 Long Non-coding RNA in Gastrointestinal Cancer
Frontiers in Oncology, 2020 Whole genome and transcriptome sequencing technologies have led to the identification of many long non-coding RNAs (lncRNAs) and stimulated the research of their role in health and disease.
Águeda Martínez-Barriocanal +4 more
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A noncoding RNA containing a SINE-B1 motif associates with meiotic metaphase chromatin and has an indispensable function during spermatogenesis. [PDF]
PLoS ONE, 2017 A search for early response genes that are activated following germ cell induction from mouse embryonic stem cells in vitro led us to the isolation of a long noncoding RNA that contains a SINE (short interspersed element)-B1F motif that was named R53. In
Ryusuke Nakajima +4 more
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Cytotopic localization by long noncoding RNAs [PDF]
Current Opinion in Cell Biology, 2013 Cells are highly organized structures. In addition to membrane delimited organelles, proteins and RNAs can organize themselves into specific domains. Some examples include stress granules and subnuclear bodies. This level of organization is essential for the correct execution of multiple processes in the cell, ranging from cell signaling to assembly of
Pedro J, Batista, Howard Y, Chang
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The Smooth Long Noncoding RNA SENCR [PDF]
Arteriosclerosis, Thrombosis, and Vascular Biology, 2014 Long noncoding RNAs (lncRNAs) have emerged as novel regulators of gene expression, but their mode of action is diverse and ill understood. There are few examples that lncRNAs are also involved in cardiovascular development as well as in cardiovascular (patho)physiology (Figure).
Thomas, Thum, Regalla, Kumarswamy
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The State of Long Non-Coding RNA Biology
Non-Coding RNA, 2018 Transcriptomic studies have demonstrated that the vast majority of the genomes of mammals and other complex organisms is expressed in highly dynamic and cell-specific patterns to produce large numbers of intergenic, antisense and intronic long non ...
John S. Mattick
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The role of miRNA and lncRNA in heterotopic ossification pathogenesis
Stem Cell Research & Therapy, 2022 Heterotopic ossification (HO) is the formation of bone in non-osseous tissues, such as skeletal muscles. The HO could have a genetic or a non-genetic (acquired) background, that is, it could be caused by musculoskeletal trauma, such as burns, fractures ...
Łukasz Pulik +6 more
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Splicing regulation by long noncoding RNAs [PDF]
Nucleic Acids Research, 2018 Massive high-throughput sequencing techniques allowed the identification of thousands of noncoding RNAs (ncRNAs) and a plethora of different mRNA processing events occurring in higher organisms. Long ncRNAs can act directly as long transcripts or can be processed into active small si/miRNAs.
Romero Barrios, Natali +4 more
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Tumor Biology, 2017 Non–small cell lung cancer is one of the most common types of cancer, and the prognosis of non–small cell lung cancer is still poor. Recent evidence has proved that long noncoding RNA is involved in tumorigenesis.
Cheng Huang +10 more
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The role of noncoding RNAs in metabolic reprogramming of cancer cells
Cellular & Molecular Biology Letters, 2023 Metabolic reprogramming is a well-known feature of cancer that allows malignant cells to alter metabolic reactions and nutrient uptake, thereby promoting tumor growth and spread.
Amir Safi +7 more
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