Results 11 to 20 of about 8,401,372 (300)
Long Noncoding RNAs in Metabolic Syndrome Related Disorders [PDF]
Mediators of Inflammation, 2016 Ribonucleic acids (RNAs) are very complex and their all functions have yet to be fully clarified. Noncoding genes (noncoding RNA, sequences, and pseudogenes) comprise 67% of all genes and they are represented by housekeeping noncoding RNAs (transfer RNA (
Magdalena Losko +2 more
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Long Noncoding RNA and Epigenomics
, 2011 Accumulating evidence over the last decade has presented us with the intriguing observation that the majority of eukaryotic genomes are pervasively transcribed to encode a complex network of small and long noncoding RNAs. Long noncoding RNAs are of particular interest, as they were once thought to be restricted to housekeeping functions and are now ...
Kanduri, Chandrasekhar,
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Boundary Associated Long Noncoding RNA Mediates Long-Range Chromosomal Interactions.
PLoS ONE, 2015 CCCTC binding factor (CTCF) is involved in organizing chromosomes into mega base-sized, topologically associated domains (TADs) along with other factors that define sub-TAD organization.
Ifeoma Jane Nwigwe +3 more
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Long noncoding RNA involvement in cancer [PDF]
BMB Reports, 2012 Recent advances in genome and transcriptome analysis haveenabled identification of numerous members of a new class ofnoncoding RNA, long noncoding RNA (lncRNA).
Reo Maruyama & Hiromu Suzuki*
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Functional insights into long antisense noncoding RNA Kcnq1ot1 mediated bidirectional silencing
, 2008 The prevailing view has been that noncoding antisense RNA primarily regulates the transcriptional activity of its sense counterpart, however, a subset of long noncoding antisense RNAs, such as Kcnq1ot1 and Air, have been shown to regulate the ...
Kanduri, Chandrasekhar,
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Long noncoding RNA: noncoding and not coded [PDF]
Cell Death Discovery, 2017 Mammalian evolution exhibits extraordinary acceleration in phenotypic complexity while displaying genetic conservation. Indeed, protein-coding genes are 90% identical between mice and human, and the question arises what might be the mechanisms by which phenotypic complexity increases while the number of proteins does not?
Toiber, Debra +2 more
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Long noncoding RNAs and atherosclerosis [PDF]
Atherosclerosis, 2016 Atherosclerosis is universally recognized as a chronic lipid-induced inflammation of the vessel wall in response to dyslipidemia and haemodynamic stress involving dysfunction and activation of resident vascular cells as well as infiltration of leukocytes.
Tian Zhou +3 more
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Annual Review of Plant Biology, 2021 Plants have an extraordinary diversity of transcription machineries, including five nuclear DNA-dependent RNA polymerases. Four of these enzymes are dedicated to the production of long noncoding RNAs (lncRNAs), which are ribonucleic acids with functions independent of their protein-coding potential.
Wierzbicki, Andrzej +2 more
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Long noncoding RNAs in hematopoiesis [PDF]
F1000Research, 2016 Mammalian development is under tight control to ensure precise gene expression. Recent studies reveal a new layer of regulation of gene expression mediated by long noncoding RNAs. These transcripts are longer than 200nt that do not have functional protein coding capacity.
Zhang, Xu, Hu, Wenqian
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Cytokines and Long Noncoding RNAs [PDF]
Cold Spring Harbor Perspectives in Biology, 2017 Cytokines and long noncoding RNAs (lncRNAs) are intertwined in the regulatory circuit controlling immunity. lncRNA expression levels are altered following cytokine stimulation in a cell-type-specific fashion. lncRNAs, in turn, regulate the inducible expression of cytokines following immune activation.
Susan, Carpenter +1 more
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