Results 31 to 40 of about 102,540 (304)

Chromosomal Translocation Formation Is Sufficient to Produce Fusion Circular RNAs Specific to Patient Tumor Cells

iScience, 2018
Summary: Circular RNAs constitute a unique class of RNAs whose precise functions remain to be elucidated. In particular, cancer-associated chromosomal translocations can give rise to fusion circular RNAs that play a role in leukemia progression. However,
Loelia Babin, Marion Piganeau, Benjamin Renouf, Khadija Lamribet, Cecile Thirant, Ludovic Deriano, Thomas Mercher, Carine Giovannangeli, Erika C. Brunet   +8 more
doaj   +1 more source

Circular RNAs and their roles in head and neck cancers

Molecular Cancer, 2019
Circular RNAs are abundant endogenous non-coding RNA with no 5′ cap and 3′ polyadenylation tail that modify liner mRNAs and have no terminal structures.
Yang Guo, Jiechao Yang, Qiang Huang, Chiyao Hsueh, Juan Zheng, Chunping Wu, Hui Chen, Liang Zhou   +7 more
doaj   +1 more source

Circ-ZNF609 regulates G1-S progression in rhabdomyosarcoma [PDF]

, 2019
Circular RNAs (circRNAs) represent a class of covalently closed RNAs, derived from non-canonical splicing events, which are expressed in all eukaryotes and often conserved among different species.
Bozzoni, Irene, Colantoni, Alessio, Dattilo, Dario, DI TIMOTEO, Gaia, Dominici, Carlo, Legnini, Ivano, Megiorni, Francesca, Morlando, Mariangela, Rossi, Francesca, Santini, Tiziana   +9 more
core   +1 more source

Circ2Traits: A comprehensive database for circular RNA potentially associated with disease and traits

Frontiers in Genetics, 2013
Circular RNAs are new players in regulation of post transcriptional gene expression. Animal genomes express many circular RNAs from diverse genomic locations.
Suman eGhosal, Shaoli eDas, Rituparno eSen, Piyali eBasak, Jayprokas eChakrabarti   +4 more
doaj   +1 more source

Circular RNA hsa_circ_0000376 Participates in Tumorigenesis of Breast Cancer by Targeting miR-1285-3p

Technology in Cancer Research & Treatment, 2020
This study was designed to identify novel circular RNAs and the related regulatory axis to provide research targets for the diagnosis and treatment of breast cancer.
Ziqi Peng BM, Boyang Xu BM, Feng Jin MD
doaj   +1 more source

Hfq binding changes the structure of Escherichia coli small noncoding RNAs OxyS and RprA, which are involved in the riboregulation of rpoS [PDF]

, 2013
OxyS and RprA are two small noncoding RNAs (sRNAs) that modulate the expression of rpoS, encoding an alternative sigma factor that activates transcription of multiple Escherichia coli stress-response genes. While RprA activates rpoS for translation, OxyS
Callaghan, Anastasia, Cary, Peter, Casamento, A., Gowers, Darren, Henderson, Charlotte, Phillips, Jack, Sobott, F., Stone, Carlanne, Taylor, James E., Vincent, H.   +9 more
core   +1 more source

Circular RNAs and Cardiovascular Regeneration [PDF]

Frontiers in Cardiovascular Medicine, 2021
circular RNAs (circRNAs) are a type of non-coding RNAs that are widely present in eukaryotic cells. They have the characteristics of stable structure, high abundance, and cell or tissue specific expression. circRNAs are single-stranded RNAs that are covalently back spliced to form closed circular loops.
Ling Tang, Pengsheng Li, Michelle Jang, Wuqiang Zhu   +3 more
openaire   +3 more sources

Silencing of circRNA.2837 Plays a Protective Role in Sciatic Nerve Injury by Sponging the miR-34 Family via Regulating Neuronal Autophagy

Molecular Therapy: Nucleic Acids, 2018
Circular RNAs (circRNAs) represent a class of non-coding RNAs that are involved in transcriptional and posttranscriptional gene expression regulation and associated with different kinds of human diseases.
Zhi-bin Zhou, Yu-long Niu, Gao-xiang Huang, Jia-jia Lu, Aimin Chen, Lei Zhu   +5 more
doaj   +1 more source

Hyb:A bioinformatics pipeline for the analysis of CLASH (crosslinking, ligation and sequencing of hybrids) data [PDF]

, 2013
Peer reviewedPublisher ...
Aiba, Aleksandra Helwak, Altschul, Anthony J. Travis, Aravin, Chi, Chi, David Tollervey, Dodt, Field, Filipowicz, Gong, Granneman, Grzegorz Kudla, Hafner, Hansen, Helwak, Jonathan Moody, Kent, Kim, Kudla, Langmead, Leung, Licatalosi, Lorenz, Markham, Memczak, Quinlan, Rost, Simpson, Ule, Wlotzka, Zhang   +32 more
core   +2 more sources

Circular RNAs in myogenesis

Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms, 2020
Skeletal muscles have an immense ability to regenerate from the muscle stem cells called satellite cells. The process of skeletal muscle regeneration is called myogenesis, which starts with activation of quiescent satellite cells immediately after muscle injury followed by proliferation and fusion of myoblasts into myotubes.
Arundhati, Das, Aniruddha, Das, Debojyoti, Das, Kotb, Abdelmohsen, Amaresh C, Panda   +4 more
openaire   +3 more sources