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Therapeutic Potential of Circular RNAs as Targets for Cancer Treatment [PDF]
Advanced Pharmaceutical BulletinCircular RNAs (circRNAs) are a novel class of non-coding RNAs primarily generated through a back-splicing processes. These molecules exhibit extensive expression across various tissues, indicating their significant role in numerous biological processes ...
Milad Asadi +8 more
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Cancer Management and Research, 2018 Shuaixi Yang,1,* Zhenqiang Sun,1,* Quanbo Zhou,1,* Weiwei Wang,2,3 Guixian Wang,1 Junmin Song,1 Zhen Li,1 Zhiyong Zhang,1 Yuan Chang,1 Kunkun Xia,1 Jinbo Liu,1 Weitang Yuan1 1Department of Colorectal Surgery, The First Affiliated Hospital of Zhengzhou ...
Yang S +11 more
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Identification of differentially expressed circular RNAs in human colorectal cancer
Tumor Biology, 2017 Circular RNA, a class of non-coding RNA, is a new group of RNAs and is related to tumorigenesis. Circular RNAs are suggested to be ideal candidate biomarkers with potential diagnostic and therapeutic implications.
Shaotang Li, Xuecheng Sun, Lei Jiang
exaly +2 more sources
Cell Reports, 2014 Summary: Circularization was recently recognized to broadly expand transcriptome complexity. Here, we exploit massive Drosophila total RNA-sequencing data, >5 billion paired-end reads from >100 libraries covering diverse developmental stages, tissues ...
Jakub O. Westholm +8 more
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The role of circular RNAs in brain and stroke
Frontiers in Bioscience-Landmark, 2021 Circular RNAs are single-stranded RNAs which are closed by covalent bonds during splicing. Different from other RNAs, circular RNAs are well known due to their circular structure. In recent years, many researches were conducted to investigate the role of
Yu-Ye Wang +3 more
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Circular RNAs in Toxicology [PDF]
Toxicological Sciences, 2020 Abstract Circular RNAs (circRNAs) are a type of closed, long, non-coding RNAs, which have attracted significant attention in recent years. CircRNAs exhibit unique functions and are characterized by stable expression in various tissues across different species.
Yueting Shao, Yiguo Jiang
openaire +2 more sources
Roles of circular RNAs in the pathogenesis and treatment of pancreatic cancer
Frontiers in Cell and Developmental Biology, 2022 Circular RNAs are single-stranded RNAs with a covalently closed structure formed by the process of back-splicing. Aberrant expression of circular RNAs contributes to the pathogenesis of a wide range of cancers. Pancreatic cancer is one of the most lethal
Takahiro Seimiya +2 more
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Veterinary Sciences, 2023 Circular RNAs are widespread in various species and have important roles in myogenesis. However, the circular RNAs involved in breast muscle development in ducks have not yet been studied.
Jing Liu +6 more
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Epigenetic Regulation by Non-Coding RNAs in the Avian Immune System
Life, 2020 The identified non-coding RNAs (ncRNAs) include circular RNAs, long non-coding RNAs, microRNAs, ribosomal RNAs, small interfering RNAs, small nuclear RNAs, piwi-interacting RNAs, and transfer RNAs, etc.
Xiaolan Chen +3 more
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Circular RNA: A promising new star for the diagnosis and treatment of colorectal cancer
Cancer Medicine, 2021 Background Colorectal cancer (CRC) is one of the most common malignant tumors of the digestive tract. According to the research of circular RNAs in the CRC field, compared with linear RNAs, circular RNAs are a special type of noncoding RNA that are ...
Shunhao Zhang +4 more
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