Results 21 to 30 of about 761,097 (299)

The Biomarker and Therapeutic Potential of Circular Rnas in Schizophrenia [PDF]

open access: yesCells, 2020
Circular RNAs (circRNAs) are endogenous, single-stranded, most frequently non-coding RNA (ncRNA) molecules that play a significant role in gene expression regulation.
Artem Nedoluzhko   +6 more
doaj   +2 more sources

MicroRNAs, long noncoding RNAs, and circular RNAs: potential tumor biomarkers and targets for colorectal cancer

open access: yesCancer Management and Research, 2018
Shuaixi Yang,1,* Zhenqiang Sun,1,* Quanbo Zhou,1,* Weiwei Wang,2,3 Guixian Wang,1 Junmin Song,1 Zhen Li,1 Zhiyong Zhang,1 Yuan Chang,1 Kunkun Xia,1 Jinbo Liu,1 Weitang Yuan1 1Department of Colorectal Surgery, The First Affiliated Hospital of Zhengzhou ...
Yang S   +11 more
doaj   +1 more source

Circular RNAs in Toxicology [PDF]

open access: yesToxicological Sciences, 2020
Abstract Circular RNAs (circRNAs) are a type of closed, long, non-coding RNAs, which have attracted significant attention in recent years. CircRNAs exhibit unique functions and are characterized by stable expression in various tissues across different species.
Yueting Shao, Yiguo Jiang
openaire   +2 more sources

Circular RNA identified from Peg3 and Igf2r. [PDF]

open access: yesPLoS ONE, 2018
Circular RNA is a newly discovered class of non-coding RNA generated through the back-splicing of linear pre-mRNA. In the current study, we characterized two circular RNAs that had been identified through NGS-based 5'RACE experiments.
Bambarendage P U Perera   +2 more
doaj   +1 more source

The Expression and Bioinformatics Analysis of Circular RNAs in Endometritis Mouse Uterus Tissues

open access: yesMolecules, 2022
Previous studies have shown that circular RNAs are directly or indirectly involved in the occurrence of various diseases by regulating gene expression. However, the acting mechanism of circular RNAs in endometritis remains unclear.
Zhiqiang Li   +5 more
doaj   +1 more source

In vitro circularization of RNA [PDF]

open access: yesRNA Biology, 2016
Over the past 2 decades, different types of circular RNAs have been discovered in all kingdoms of life, and apparently, those circular species are more abundant than previously thought. Apart from circRNAs in viroids and viruses, circular transcripts have been discovered in rodents more than 20 y ago and recently have been reported to be abundant in ...
Sabine, Müller, Bettina, Appel
openaire   +2 more sources

Structural insights into the dynamics and function of the C-terminus of the E. coli RNA chaperone Hfq [PDF]

open access: yes, 2011
The hexameric Escherichia coli RNA chaperone Hfq (Hfq(Ec)) is involved in riboregulation of target mRNAs by small trans-encoded RNAs. Hfq proteins of different bacteria comprise an evolutionarily conserved core, whereas the C-terminus is variable in ...
Beich-Frandsen, Mads (Department of Structural and Computational Biology, Centre for Molecular Biology, University of Vienna)   +46 more
core   +1 more source

Circular RNAs in leukemia

open access: yesAging, 2019
In pace with the development of gene sequencing technology and transcriptome research, it has been found that 70 to 90% of the human genome is transcribed into RNAs, while only 2% of RNAs encode proteins. This implies that non-coding RNAs (ncRNAs) may exert vital biological functions and a full analysis of non-coding transcriptomes is needed.
Wu, Zijuan   +3 more
openaire   +2 more sources

Identification of Circular RNAs From the Parental Genes Involved in Multiple Aspects of Cellular Metabolism in Barley

open access: yesFrontiers in Plant Science, 2016
RNA circularization made by head-to-tail back-splicing events is involved in the regulation of gene expression from transcriptional to post-translational levels.
Behrooz eDarbani   +2 more
doaj   +1 more source

CircRNA: functions and properties of a novel potential biomarker for cancer

open access: yesMolecular Cancer, 2017
Circular RNAs, a novel class of endogenous noncoding RNAs, are characterized by their covalently closed loop structures without a 5′ cap or a 3′ Poly A tail.
Shujuan Meng   +6 more
doaj   +1 more source

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