Results 21 to 30 of about 102,540 (304)

Circular RNAs as Promising Biomarkers: A mini-review

Frontiers in Physiology, 2016
The interest in circular RNAs has resurfaced in the past few years. What was considered as junk for nearly two decades is now one of the most interesting molecules.
Nadiah Abu, Rahman Jamal
doaj   +1 more source

Circular RNAs: Non-Canonical Observations on Non-Canonical RNAs

Cells, 2023
The existence of circular RNA (circRNA) research in mainstream science can be attributed to the contemporary synergism of big data and keen attention to detail by several research groups worldwide.
Brett W. Stringer, Laura Gantley, Simon J. Conn   +2 more
doaj   +1 more source

New technologies accelerate the exploration of non-coding RNAs in horticultural plants. [PDF]

, 2017
Non-coding RNAs (ncRNAs), that is, RNAs not translated into proteins, are crucial regulators of a variety of biological processes in plants. While protein-encoding genes have been relatively well-annotated in sequenced genomes, accounting for a small ...
Hu, Rongbin, Liu, Degao, Mewalal, Ritesh, Tuskan, Gerald A, Yang, Xiaohan   +4 more
core   +3 more sources

Identification of Circular RNAs From the Parental Genes Involved in Multiple Aspects of Cellular Metabolism in Barley

Frontiers in Plant Science, 2016
RNA circularization made by head-to-tail back-splicing events is involved in the regulation of gene expression from transcriptional to post-translational levels.
Behrooz eDarbani, Shahin eNoeparvar, Søren eBorg   +2 more
doaj   +1 more source

Circular RNAs in Clear Cell Renal Cell Carcinoma: Their Microarray-Based Identification, Analytical Validation, and Potential Use in a Clinico-Genomic Model to Improve Prognostic Accuracy [PDF]

, 2019
Circular RNAs (circRNAs) may act as novel cancer biomarkers. However, a genome-wide evaluation of circRNAs in clear cell renal cell carcinoma (ccRCC) has yet to be conducted. Therefore, the objective of this study was to identify and validate circRNAs in
Erbersdobler, Andreas, Fendler, Annika, Franz, Antonia, Jung, Klaus, Jung, Monika, Kilic, Ergin, Ralla, Bernhard, Rochow, Hannah, Stephan, Carsten, Weickmann, Sabine   +9 more
core   +2 more sources

CircRNA: functions and properties of a novel potential biomarker for cancer

Molecular Cancer, 2017
Circular RNAs, a novel class of endogenous noncoding RNAs, are characterized by their covalently closed loop structures without a 5′ cap or a 3′ Poly A tail.
Shujuan Meng, Hecheng Zhou, Ziyang Feng, Zihao Xu, Ying Tang, Peiyao Li, Minghua Wu   +6 more
doaj   +1 more source

Diagnostic Accuracy of Circular RNAs in Different Types of Samples for Detecting Hepatocellular Carcinoma: A Meta-Analysis

Frontiers in Genetics, 2021
The lack of accurate biomarkers impeded the screening, diagnosis and early treatment of hepatocellular carcinoma (HCC). As a result of the development of high-throughput transcriptome analysis techniques, circular RNAs, a newly discovered class of ...
Guilin Nie, Dingzhong Peng, Bei Li, Jiong Lu, Xianze Xiong   +4 more
doaj   +1 more source

Interaction and cross-talk between non-coding RNAs. [PDF]

, 2017
Non-coding RNA (ncRNA) has been shown to regulate diverse cellular processes and functions through controlling gene expression. Long non-coding RNAs (lncRNAs) act as a competing endogenous RNAs (ceRNAs) where microRNAs (miRNAs) and lncRNAs regulate each ...
Dahiya, Rajvir, Imai-Sumida, Mitsuho, Tanaka, Yuichiro, Yamamura, Soichiro   +3 more
core   +2 more sources

Circ-ZNF609 Is a Circular RNA that Can Be Translated and Functions in Myogenesis [PDF]

, 2017
Circular RNAs (circRNAs) constitute a family of transcripts with unique structures and still largely unknown functions. Their biogenesis, which proceeds via a back-splicing reaction, is fairly well characterized, whereas their role in the modulation of ...
Andronache, Adrian, Bozzoni, Irene, Briganti, Francesca, DI TIMOTEO, Gaia, Fatica, Alessandro, Laneve, Pietro, Legnini, Ivano, Morlando, Mariangela, Rajewsky, Nikolaus, Rossi, Francesca, Santini, Tiziana, Sthandier, Olga Elena, Wade, Mark   +12 more
core   +3 more sources

Engineering circular RNA regulators to specifically promote circular RNA production

Theranostics, 2021
Background: A large number of circular RNAs (circRNAs) have been discovered in the mammalian transcriptome with high abundance, which play vital roles in gene regulation, thereby participating in the development of multiple diseases. However, the biogenesis, regulation, and especially manipulation of circRNAs still remain largely unknown.
Qi, Yangfan, Han, Wei, Chen, Dan, Zhao, Jinyao, Bai, Lu, Huang, Fang, Dai, Zhenwei, Li, Gang, Chen, Chaoqun, Zhang, Wenjing, Zhang, Jinrui, Jin, Bilian, Wang, Yang   +12 more
openaire   +2 more sources