Results 21 to 30 of about 63,453 (262)

Circular RNAs: Non-Canonical Observations on Non-Canonical RNAs

open access: yesCells, 2023
The existence of circular RNA (circRNA) research in mainstream science can be attributed to the contemporary synergism of big data and keen attention to detail by several research groups worldwide.
Brett W. Stringer   +2 more
doaj   +1 more source

Identification of Circular RNAs From the Parental Genes Involved in Multiple Aspects of Cellular Metabolism in Barley

open access: yesFrontiers in Plant Science, 2016
RNA circularization made by head-to-tail back-splicing events is involved in the regulation of gene expression from transcriptional to post-translational levels.
Behrooz eDarbani   +2 more
doaj   +1 more source

CircRNA: functions and properties of a novel potential biomarker for cancer

open access: yesMolecular Cancer, 2017
Circular RNAs, a novel class of endogenous noncoding RNAs, are characterized by their covalently closed loop structures without a 5′ cap or a 3′ Poly A tail.
Shujuan Meng   +6 more
doaj   +1 more source

Diagnostic Accuracy of Circular RNAs in Different Types of Samples for Detecting Hepatocellular Carcinoma: A Meta-Analysis

open access: yesFrontiers in Genetics, 2021
The lack of accurate biomarkers impeded the screening, diagnosis and early treatment of hepatocellular carcinoma (HCC). As a result of the development of high-throughput transcriptome analysis techniques, circular RNAs, a newly discovered class of ...
Guilin Nie   +4 more
doaj   +1 more source

Interior circular RNA [PDF]

open access: yesRNA Biology, 2019
Formed by back splicing or back fusion of linear RNAs, circular RNAs (circRNAs) constitute a new class of non-coding RNAs of eukaryotes. Recent studies reveal a spliceosome-dependent biogenesis of circRNAs where circRNAs arise at the intron-exon junctions of mRNAs.
Xiaoxin Liu   +10 more
openaire   +2 more sources

Chromosomal Translocation Formation Is Sufficient to Produce Fusion Circular RNAs Specific to Patient Tumor Cells

open access: yesiScience, 2018
Summary: Circular RNAs constitute a unique class of RNAs whose precise functions remain to be elucidated. In particular, cancer-associated chromosomal translocations can give rise to fusion circular RNAs that play a role in leukemia progression. However,
Loelia Babin   +8 more
doaj   +1 more source

Circular RNAs in and out of Cells: Therapeutic Usages of Circular RNAs

open access: yesMolecules and Cells, 2023
RNAs are versatile molecules that are primarily involved in gene regulation and can thus be widely used to advance the fields of therapeutics and diagnostics. In particular, circular RNAs which are highly stable, have emerged as strong candidates for use on next-generation therapeutic platforms. Endogenous circular RNAs control gene regulatory networks
Mingyu Ju   +3 more
openaire   +2 more sources

Circular RNAs and their roles in head and neck cancers

open access: yesMolecular Cancer, 2019
Circular RNAs are abundant endogenous non-coding RNA with no 5′ cap and 3′ polyadenylation tail that modify liner mRNAs and have no terminal structures.
Yang Guo   +7 more
doaj   +1 more source

Circ2Traits: A comprehensive database for circular RNA potentially associated with disease and traits

open access: yesFrontiers in Genetics, 2013
Circular RNAs are new players in regulation of post transcriptional gene expression. Animal genomes express many circular RNAs from diverse genomic locations.
Suman eGhosal   +4 more
doaj   +1 more source

Circular RNA hsa_circ_0000376 Participates in Tumorigenesis of Breast Cancer by Targeting miR-1285-3p

open access: yesTechnology in Cancer Research & Treatment, 2020
This study was designed to identify novel circular RNAs and the related regulatory axis to provide research targets for the diagnosis and treatment of breast cancer.
Ziqi Peng BM, Boyang Xu BM, Feng Jin MD
doaj   +1 more source

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