Results 41 to 50 of about 32,863 (251)

Exosomes and Exosomal circRNAs: The Rising Stars in the Progression, Diagnosis and Prognosis of Gastric Cancer

open access: yesCancer Management and Research, 2021
Ling Lu,1,* Shikun Fang,2,* Yue Zhang,2 Longtao Jin,1 Wenrong Xu,2 Zhaofeng Liang2 1Child Healthcare Department, The Fourth Affiliated Hospital of Jiangsu University, Zhenjiang, Jiangsu, 212001, People’s Republic of China; 2Jiangsu Key Laboratory
Lu L   +5 more
doaj  

Expression and function of CCN2-derived circRNAs in chondrocytes [PDF]

open access: yes, 2023
Cellular communication network factor 2 (CCN2) molecules promote endochondral ossification and articular cartilage regeneration, and circular RNAs (circRNAs), which arise from various genes and regulate gene expression by adsorbing miRNAs, are known to ...
Iida, Seiji   +6 more
core   +2 more sources

Elucidating the regulation and function of circRNAs

open access: yes, 2022
Circular RNAs (circRNAs) are a newly appreciated class of RNAs that are expressed in a wide range of organisms, tissues, and disease states. The factors regulating circRNA biogenesis are poorly understood.
Knupp, David
core   +2 more sources

CircZNF609 as a prototype to elucidate the biological function of circRNA-mRNA interactions

open access: yesMolecular & Cellular Oncology, 2022
Circular RNAs (circRNAs) are expressed and are regulated in many biological processes but little is known about their ability to directly control mRNA homeostasis.
Manuel Beltran   +2 more
doaj   +1 more source

Systematic Identification of circRNAs in Alzheimer’s Disease

open access: yes, 2021
Mammalian circRNAs are covalently closed circular RNAs often generated through backsplicing of precursor linear RNAs. Although their functions are largely unknown, they have been found to influence gene expression at different levels and in a wide range ...
Gautam Kundu   +7 more
core   +1 more source

Identification of circular RNA expression profiles in renal fibrosis induced by obstructive injury

open access: yesRenal Failure, 2021
Introduction Advancing renal fibrosis is the common histopathological feature of chronic obstructive nephropathy, representing the final pathway of nearly all chronic and progressive nephropathies.
Jiangju Huang   +7 more
doaj   +1 more source

Microarray Expression Profile of Exosomal circRNAs from High Glucose Stimulated Human Renal Tubular Epithelial Cells

open access: yes, 2023
Yan-Hua Sha,1 Song-Ling Cao,1 Lu Zhang,2 Li-Sha Lai,2 Pei-Feng Ke,1 Ke-Wei Yu,1 Xiu-Zhu Fang,2 Ren-Tang Deng,2 Ze-Min Wan,1 Xiao-Bin Wu,1 Guang Han,1 Yu-Bang Jie,2 Lan-Lan Song,2 Xian-Zhang Huang,1 Wen-Jin Fu2 1Department of Laboratory Medicine, The ...
Lai LS   +14 more
core  

CircPrimer 2.0: a software for annotating circRNAs and predicting translation potential of circRNAs

open access: yesBMC Bioinformatics, 2022
Abstract Background Some circular RNAs (circRNAs) can be translated into functional peptides by small open reading frames (ORFs) in a cap-independent manner. Internal ribosomal entry site (IRES) and N6-methyladenosine (m6A) were reported to drive translation of circRNAs.
Shanliang Zhong, Jifeng Feng
openaire   +3 more sources

Construction of circRNA–miRNA–mRNA Network Reveal Functional circRNAs and Key Genes in Acute Myeloid Leukemia

open access: yes, 2023
Lianbo Hu,1 Bingrong Zheng,2 Yang Yang,2 Chunmei Chen,2 Meiwei Hu2 1Physical Examination Center, Affiliated Hangzhou First People’s Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, People’s Republic of China; 2Department of ...
Yang Y, Hu M, Zheng B, Hu L, Chen C
core  

CircRNAS expression profile in colorectal cancer

open access: yes, 2022
Os RNAs circulares (circRNAs) são uma nova classe de RNA que forma laços (loops) contínuos fechados covalentemente. Como os RNAs longos e não codificadores, as funções efetivas dos circRNAs dependem principalmente das características de suas sequências e
Freitas, Vanessa Galdeno
core   +1 more source

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