Results 31 to 40 of about 25,680 (233)
Research Progress on Energy Metabolism and Radiosensitivity of Glioma
Zhongliu Fangzhi Yanjiu, 2021 Radiotherapy is an important auxiliary treatment for glioma. Although comprehensive treatment of glioma has made some progress in recent years, the prognosis is still poor.
MOU Fuling, ZHONG Jiawei, SUN Pengfei
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CircPrimer: a software for annotating circRNAs and determining the specificity of circRNA primers [PDF]
BMC Bioinformatics, 2018 Since circular RNAs (circRNAs) post-transcriptionally regulate gene expression, they have attracted increasing attention. However, there is no existing tool to annotate and extract spliced sequences for circRNAs and no tool to determine the specificity of circRNA primers.In this study, we present circPrimer, which allows users to search, annotate, and ...
Shanliang Zhong +4 more
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Cancer Management and Research, 2021 Ling Lu,1,* Shikun Fang,2,* Yue Zhang,2 Longtao Jin,1 Wenrong Xu,2 Zhaofeng Liang2 1Child Healthcare Department, The Fourth Affiliated Hospital of Jiangsu University, Zhenjiang, Jiangsu, 212001, People’s Republic of China; 2Jiangsu Key Laboratory
Lu L +5 more
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CircZNF609 as a prototype to elucidate the biological function of circRNA-mRNA interactions
Molecular & Cellular Oncology, 2022 Circular RNAs (circRNAs) are expressed and are regulated in many biological processes but little is known about their ability to directly control mRNA homeostasis.
Manuel Beltran +2 more
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Identification of circular RNA expression profiles in renal fibrosis induced by obstructive injury
Renal Failure, 2021 Introduction Advancing renal fibrosis is the common histopathological feature of chronic obstructive nephropathy, representing the final pathway of nearly all chronic and progressive nephropathies.
Jiangju Huang +7 more
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CircRNAs: Insights into Gastric Cancer [PDF]
Gastrointestinal Tumors, 2021 <b><i>Background:</i></b> Gastric cancer (GC) is recorded as the fifth most common cancer globally. The classic resemblance of early symptoms of chronic gastritis including nausea, dysphagia, and dyspepsia with GC is the current challenge limiting the early diagnosis of GC. The current diagnostic procedures of GC are limited due
Sanjana, Rajgopal +2 more
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CircPrimer 2.0: a software for annotating circRNAs and predicting translation potential of circRNAs
BMC Bioinformatics, 2022 Abstract Background Some circular RNAs (circRNAs) can be translated into functional peptides by small open reading frames (ORFs) in a cap-independent manner. Internal ribosomal entry site (IRES) and N6-methyladenosine (m6A) were reported to drive translation of circRNAs.
Shanliang Zhong, Jifeng Feng
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CircRNAs and Fusion-circRNAs in cancer: New players in an old game
Cellular Signalling, 2020 Circular RNAs (circRNAs) are generated from 'back-splicing' events. Their circular structure makes them stable in cells and body fluids. These entities are involved in several human diseases including cancer, as they affect the expression of genes promoting proliferation, invasion, apoptosis, and angiogenesis.
Grazia Visci +5 more
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Impact of exosomal and cell-free circRNAs on cancer drug resistance [PDF]
ExRNACancer is the most lethal disease in humans. Despite substantial advancements in cancer therapy during the last decades, the effectiveness of chemotherapeutic agents is limited since many patients develop drug resistance.
Heidi Schwarzenbach
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Roles of circRNAs in the tumour microenvironment [PDF]
Molecular Cancer, 2020 Abstract The tumour microenvironment (TME) constitutes the area surrounding the tumour during its development and has been demonstrated to play roles in cancer-related diseases through crosstalk with tumour cells. Circular RNAs (circRNAs) are a subpopulation of endogenous noncoding RNAs (ncRNAs) that are ubiquitously expressed in ...
Qiuge Zhang +7 more
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