Results 31 to 40 of about 36,533 (268)

Research Progress on Energy Metabolism and Radiosensitivity of Glioma

Zhongliu Fangzhi Yanjiu, 2021
Radiotherapy is an important auxiliary treatment for glioma. Although comprehensive treatment of glioma has made some progress in recent years, the prognosis is still poor.
MOU Fuling, ZHONG Jiawei, SUN Pengfei
doaj   +1 more source

Circ-ZNF609 Is a Circular RNA that Can Be Translated and Functions in Myogenesis [PDF]

, 2017
Circular RNAs (circRNAs) constitute a family of transcripts with unique structures and still largely unknown functions. Their biogenesis, which proceeds via a back-splicing reaction, is fairly well characterized, whereas their role in the modulation of ...
Andronache, Adrian, Bozzoni, Irene, Briganti, Francesca, DI TIMOTEO, Gaia, Fatica, Alessandro, Laneve, Pietro, Legnini, Ivano, Morlando, Mariangela, Rajewsky, Nikolaus, Rossi, Francesca, Santini, Tiziana, Sthandier, Olga Elena, Wade, Mark   +12 more
core   +3 more sources

circRNA meets gene amplification [PDF]

Non-coding RNA Investigation, 2018
Lung cancer remains the most common cause of cancer related death among both males and females globally accounting for 1.69 million deaths in 2015 (1). Of the different types of lung cancer, lung adenocarcinoma (LAC) is the most common (2). Given the prevalence and lethality of lung cancer the need to elucidate the mechanisms of this disease and to ...
Nicholas, Manguso, Armando E, Giuliano, Hisashi, Tanaka   +2 more
openaire   +2 more sources

Circ-ZNF609 regulates G1-S progression in rhabdomyosarcoma [PDF]

, 2019
Circular RNAs (circRNAs) represent a class of covalently closed RNAs, derived from non-canonical splicing events, which are expressed in all eukaryotes and often conserved among different species.
Bozzoni, Irene, Colantoni, Alessio, Dattilo, Dario, DI TIMOTEO, Gaia, Dominici, Carlo, Legnini, Ivano, Megiorni, Francesca, Morlando, Mariangela, Rossi, Francesca, Santini, Tiziana   +9 more
core   +1 more source

Profiling and bioinformatics analyses reveal differential circular RNA expression in hypertensive patients

Clinical and Experimental Hypertension, 2017
Objectives: CircRNAs, a novel class of noncoding RNAs, have been reported in many diseases. However, their role in hypertension remains unclear. Here, we aimed to determine the circRNA expression profile in hypertension patients and further construct a ...
Na Wu, Ling Jin, Jun Cai
doaj   +1 more source

Differential Expression of Circular RNAs in Polytocous and Monotocous Uterus during the Reproductive Cycle of Sheep

Animals, 2019
CircRNA plays important roles in cell proliferation, differentiation, autophagy and apoptosis during development. However, there are few reports on circRNAs related to livestock reproduction.
Yongfu La, Jishun Tang, Ran Di, Xiangyu Wang, Qiuyue Liu, Liping Zhang, Xiaosheng Zhang, Jinlong Zhang, Wenping Hu, Mingxing Chu   +9 more
doaj   +1 more source

CircZNF609 as a prototype to elucidate the biological function of circRNA-mRNA interactions

Molecular & Cellular Oncology, 2022
Circular RNAs (circRNAs) are expressed and are regulated in many biological processes but little is known about their ability to directly control mRNA homeostasis.
Manuel Beltran, Francesca Rossi, Irene Bozzoni   +2 more
doaj   +1 more source

Deregulation of CircANXA2, Circ0075001, and CircFBXW7 Gene Expressions and Their Predictive Value in Egyptian Acute Myeloid Leukemia Patients

The Application of Clinical Genetics, 2022
Safaa I Tayel,1 Shimaa E Soliman,1 Iman A Ahmedy,2 Mohamed Abdelhafez,3 Aly M Elkholy,3 Amira Hegazy,4 Nashwa M Muharram1 1Medical Biochemistry and Molecular Biology Department, Faculty of Medicine, Menoufia University, Shebin El-Kom, 32511, Egypt ...
Tayel SI, Soliman SE, Ahmedy IA, Abdelhafez M, Elkholy AM, Hegazy A, Muharram NM   +6 more
doaj  

FUS affects circular RNA expression in murine embryonic stem cell-derived motor neurons [PDF]

, 2017
The RNA-binding protein FUS participates in several RNA biosynthetic processes and has been linked to the pathogenesis of amyotrophic lateral sclerosis (ALS) and frontotemporal dementia.
Bozzoni, Irene, Caffarelli, Elisa, Capauto, Davide, Colantoni, Alessio, DE SANTIS, Riccardo, DINI MODIGLIANI, Stefano, Errichelli, Lorenzo, Laneve, Pietro, Legnini, Ivano, Lu, Lei, Morlando, Mariangela, Peruzzi, Giovanna, Rosa, Alessandro, Scarfò, Rebecca, Shneider, Neil A.   +14 more
core   +1 more source

Identification of circular RNA expression profiles in renal fibrosis induced by obstructive injury

Renal Failure, 2021
Introduction Advancing renal fibrosis is the common histopathological feature of chronic obstructive nephropathy, representing the final pathway of nearly all chronic and progressive nephropathies.
Jiangju Huang, Zhihao Zhang, Benquan Liu, Ying Gao, Jiayi Nie, Shihong Wen, Xiaohong Lai, Hua Liang   +7 more
doaj   +1 more source