Results 31 to 40 of about 32,863 (251)

Interactions of circRNAs with methylation: An important aspect of circRNA biogenesis and function (Review)

open access: yesMolecular Medicine Reports, 2022
Circular RNA (circRNA) molecules are noncoding RNAs with unique circular covalently closed structures that contribute to gene expression regulation, protein translation and act as microRNA sponges. circRNAs also have important roles in human disease, particularly tumorigenesis and antitumor processes.
Zhang, Chunlei   +8 more
openaire   +2 more sources

Analysis of circRNAs and circRNA-associated competing endogenous RNA networks in β-thalassemia [PDF]

open access: yesScientific Reports, 2022
AbstractThe involvement of circRNAs in β-thalassemia and their actions on fetal hemoglobin (HbF) is unclear. Here, the circRNAs in β-thalassemia carriers with high HbF levels were comprehensively analyzed and compared with those of healthy individuals.
Fang Yang   +9 more
openaire   +3 more sources

CircRNA expression profile and circRNA-miRNA-mRNA crosstalk in allergic rhinitis [PDF]

open access: yesWorld Allergy Organization Journal, 2020
Circular RNAs (circRNAs) are involved in inflammation; however, their role in allergic rhinitis (AR) remains unclear. In this study, we analyzed circRNA expression and identified a circRNA-miRNA-mRNA network through which circRNAs regulate AR pathogenesis.We analyzed circRNA, miRNA, and mRNA expression profiles in the nasal mucosa by high-throughput ...
Chang-Yu Qiu   +7 more
openaire   +3 more sources

Functional Roles and Biological Mechanisms of Circular RNAs and Their Encoded Peptides in Glioma: A Narrative Review

open access: yesInternational Clinical Neuroscience Journal, 2021
Circular RNAs (circRNAs) are a complicated class of non-coding RNAs that have a covalently closed loop structure and are very stable and cautious. Multiple biological processes of malignancy, including tumorigenesis, development, invasion, metastasis ...
Seyedeh Zahra Bakhti   +3 more
doaj   +1 more source

Functional analysis of validated circRNAs.

open access: yes, 2023
(A) GO enrichment analysis of the upregulated circRNA parental genes. The Y axis represents log10 (P value). The X axis indicates the top 10 GO terms corresponding to the upregulated circRNAs.
Qingshi Chen (14037195)   +4 more
core   +1 more source

Circular RNAs Hsa_circ_101555 and Hsa_circ_008068 as Diagnostic Biomarkers for Early-Stage Lung Adenocarcinoma

open access: yesInternational Journal of General Medicine, 2022
Xue Lian,1,2 Dakui Cao,2 Xun Hu,3 Weiqiang Mo,2 Xiujuan Yao,4 Juanfen Mo,5 Haiqin Wang1,2 1Department of Respiratory Medicine, Bengbu Medical College, Bengbu, Anhui, 233000, People’s Republic of China; 2Department of Respiratory Medicine, The Second ...
Lian X   +6 more
doaj  

Venn diagram of overlapped differentially expressed circRNAs among circRNAs of circRNA datasets, miRNA datasets and mRNA datasets.

open access: yes, 2023
a) Overlapped differentially expressed circRNAs among circRNAs of circRNA datasets, miRNA datasets and mRNA datasets (whole genes). b) Overlapped differentially expressed circRNAs among circRNAs of circRNA datasets, miRNA datasets and mRNA datasets ...
Anam Naz (800890)   +12 more
core   +1 more source

Differential Expression of Circular RNAs in Polytocous and Monotocous Uterus during the Reproductive Cycle of Sheep

open access: yesAnimals, 2019
CircRNA plays important roles in cell proliferation, differentiation, autophagy and apoptosis during development. However, there are few reports on circRNAs related to livestock reproduction.
Yongfu La   +9 more
doaj   +1 more source

Research Progress on Energy Metabolism and Radiosensitivity of Glioma

open access: yesZhongliu Fangzhi Yanjiu, 2021
Radiotherapy is an important auxiliary treatment for glioma. Although comprehensive treatment of glioma has made some progress in recent years, the prognosis is still poor.
MOU Fuling, ZHONG Jiawei, SUN Pengfei
doaj   +1 more source

CircPrimer: a software for annotating circRNAs and determining the specificity of circRNA primers [PDF]

open access: yesBMC Bioinformatics, 2018
Since circular RNAs (circRNAs) post-transcriptionally regulate gene expression, they have attracted increasing attention. However, there is no existing tool to annotate and extract spliced sequences for circRNAs and no tool to determine the specificity of circRNA primers.In this study, we present circPrimer, which allows users to search, annotate, and ...
Shanliang Zhong   +4 more
openaire   +3 more sources

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