Results 31 to 40 of about 31,091 (262)

Functional Roles and Biological Mechanisms of Circular RNAs and Their Encoded Peptides in Glioma: A Narrative Review

open access: yesInternational Clinical Neuroscience Journal, 2021
Circular RNAs (circRNAs) are a complicated class of non-coding RNAs that have a covalently closed loop structure and are very stable and cautious. Multiple biological processes of malignancy, including tumorigenesis, development, invasion, metastasis ...
Seyedeh Zahra Bakhti   +3 more
doaj   +1 more source

Functional analysis of validated circRNAs.

open access: yes, 2023
(A) GO enrichment analysis of the upregulated circRNA parental genes. The Y axis represents log10 (P value). The X axis indicates the top 10 GO terms corresponding to the upregulated circRNAs.
Qingshi Chen (14037195)   +4 more
core   +1 more source

Interactions of circRNAs with methylation: An important aspect of circRNA biogenesis and function (Review)

open access: yesMolecular Medicine Reports, 2022
Circular RNA (circRNA) molecules are noncoding RNAs with unique circular covalently closed structures that contribute to gene expression regulation, protein translation and act as microRNA sponges. circRNAs also have important roles in human disease, particularly tumorigenesis and antitumor processes.
Zhang, Chunlei   +8 more
openaire   +2 more sources

Analysis of circRNAs and circRNA-associated competing endogenous RNA networks in β-thalassemia [PDF]

open access: yesScientific Reports, 2022
AbstractThe involvement of circRNAs in β-thalassemia and their actions on fetal hemoglobin (HbF) is unclear. Here, the circRNAs in β-thalassemia carriers with high HbF levels were comprehensively analyzed and compared with those of healthy individuals.
Fang Yang   +9 more
openaire   +3 more sources

Circular RNAs Hsa_circ_101555 and Hsa_circ_008068 as Diagnostic Biomarkers for Early-Stage Lung Adenocarcinoma

open access: yesInternational Journal of General Medicine, 2022
Xue Lian,1,2 Dakui Cao,2 Xun Hu,3 Weiqiang Mo,2 Xiujuan Yao,4 Juanfen Mo,5 Haiqin Wang1,2 1Department of Respiratory Medicine, Bengbu Medical College, Bengbu, Anhui, 233000, People’s Republic of China; 2Department of Respiratory Medicine, The Second ...
Lian X   +6 more
doaj  

Regulation of circRNA biogenesis [PDF]

open access: yesRNA Biology, 2015
Unlike linear RNAs terminated with 5' caps and 3' tails, circular RNAs are characterized by covalently closed loop structures with neither 5' to 3' polarity nor polyadenylated tail. This intrinsic characteristic has led to the general under-estimation of the existence of circular RNAs in previous polyadenylated transcriptome analyses.
Ling-Ling, Chen, Li, Yang
openaire   +2 more sources

Differential Expression of Circular RNAs in Polytocous and Monotocous Uterus during the Reproductive Cycle of Sheep

open access: yesAnimals, 2019
CircRNA plays important roles in cell proliferation, differentiation, autophagy and apoptosis during development. However, there are few reports on circRNAs related to livestock reproduction.
Yongfu La   +9 more
doaj   +1 more source

Research Progress on Energy Metabolism and Radiosensitivity of Glioma

open access: yesZhongliu Fangzhi Yanjiu, 2021
Radiotherapy is an important auxiliary treatment for glioma. Although comprehensive treatment of glioma has made some progress in recent years, the prognosis is still poor.
MOU Fuling, ZHONG Jiawei, SUN Pengfei
doaj   +1 more source

CircPrimer: a software for annotating circRNAs and determining the specificity of circRNA primers [PDF]

open access: yesBMC Bioinformatics, 2018
Since circular RNAs (circRNAs) post-transcriptionally regulate gene expression, they have attracted increasing attention. However, there is no existing tool to annotate and extract spliced sequences for circRNAs and no tool to determine the specificity of circRNA primers.In this study, we present circPrimer, which allows users to search, annotate, and ...
Shanliang Zhong   +4 more
openaire   +3 more sources

Exosomes and Exosomal circRNAs: The Rising Stars in the Progression, Diagnosis and Prognosis of Gastric Cancer

open access: yesCancer Management and Research, 2021
Ling Lu,1,* Shikun Fang,2,* Yue Zhang,2 Longtao Jin,1 Wenrong Xu,2 Zhaofeng Liang2 1Child Healthcare Department, The Fourth Affiliated Hospital of Jiangsu University, Zhenjiang, Jiangsu, 212001, People’s Republic of China; 2Jiangsu Key Laboratory
Lu L   +5 more
doaj  

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