Results 1 to 10 of about 221,688 (170)

Glioblastoma and MiRNAs [PDF]

open access: yesCancers, 2021
Glioblastoma (GB) is one of the most common types of lethal brain tumors. Although several treatment options are available including surgery, along with adjuvant chemo and radiotherapy, the disease has a poor prognosis and patients generally die within 14 months of diagnosis. GB is chemo and radio resistant.
Swalih P. Ahmed   +2 more
openaire   +3 more sources

Functional Roles of lncRNAs in Recurrent Pregnancy Loss: A Review Study [PDF]

open access: yesInternational Journal of Fertility and Sterility, 2023
Recurrent pregnancy loss (RPL) or recurrent miscarriage is the failure of pregnancy before 20-24 weeks that influencesaround 2-5% of couples. Several genetic, immunological, environmental and physical factors may influenceRPL.
Shirin Azizidoost   +7 more
doaj   +1 more source

Adult Neural Stem Cell Regulation by Small Non-coding RNAs: Physiological Significance and Pathological Implications

open access: yesFrontiers in Cellular Neuroscience, 2022
The adult neurogenic niches are complex multicellular systems, receiving regulatory input from a multitude of intracellular, juxtacrine, and paracrine signals and biological pathways. Within the niches, adult neural stem cells (aNSCs) generate astrocytic
Amber Penning   +7 more
doaj   +1 more source

Epigenetic Mechanisms in Vascular Inflammation: Modulation of Endothelial Adhesion Molecules and Endothelium-Leukocyte Adhesion

open access: yesFrontiers in Bioscience-Landmark, 2023
The endothelium, an essential component of the vascular system, plays a critical role in the inflammatory response. Under pro-inflammatory stimuli, endothelial cells undergo activation and dysfunction, leading to the release of inflammatory mediators and
Nadia Calabriso   +5 more
doaj   +1 more source

Integrative Analysis of miRNA-mRNA and miRNA-miRNA Interactions [PDF]

open access: yesBioMed Research International, 2014
MicroRNAs (miRNAs) are small, noncoding regulatory molecules. They are involved in many essential biological processes and act by suppressing gene expression. The present work reports an integrative analysis of miRNA-mRNA and miRNA-miRNA interactions and their regulatory patterns using high-throughput miRNA and mRNA datasets. Aberrantly expressed miRNA
Guo, Li   +4 more
openaire   +2 more sources

The Tumor Cytosol miRNAs, Fluid miRNAs, and Exosome miRNAs in Lung Cancer [PDF]

open access: yesFrontiers in Oncology, 2015
The focus of this review is to provide an update on the progress of microRNAs (miRNAs) as potential biomarkers for lung cancer. miRNAs are single-stranded, small non-coding RNAs that regulate gene expression and show tissue-specific signatures. Accumulating evidence indicates that miRNA expression patterns represent the in vivo status in physiology and
Xin eQin   +4 more
openaire   +5 more sources

Cellular and molecular basis of thyroid autoimmunity

open access: yesEuropean Thyroid Journal, 2023
Autoimmune thyroid disease (AITD) is the most common human autoimmune disease. The two major clinical manifestations of AITD are Graves’ disease and Hashimoto’s thyroiditis (HT).
Joanna Bogusławska   +3 more
doaj   +1 more source

Biological properties and therapeutic effects of plant-derived nanovesicles

open access: yesOpen Medicine, 2020
Exosomes-like nanoparticles can be released by a variety of plants and vegetables. The relevance of plant-derived nanovesicles (PDNVs) in interspecies communication is derived from their content in biomolecules (lipids, proteins, and miRNAs), absence of ...
Di Gioia Sante   +2 more
doaj   +1 more source

MiR-548d-3p Regulates IL-1β Expression in Human Keratoconic Corneal Fibroblasts under Oxidative Stress

open access: yesTaiyuan Ligong Daxue xuebao, 2021
Oxidative stress and inflammatory factors are closely related to keratoconus. As an important gene expression regulator, MiRNAs participate in the physiological and pathological process of keratoconus.
Sijia WANG   +8 more
doaj   +1 more source

THE ALBANIAN FACTOR OF DESTABILIZATION OF THE WESTERN BALKANS: SCENARIO APPROACH

open access: yesVestnik MGIMO-Universiteta, 2018
The Albanian factor of the Balkan policy, which received its first institutional design in the late 19th century – “Prizrenskaya League”, is currently a serious destructor of the situation in the Western Balkans (Albania, Bosnia and Herzegovina (BiH ...
E. G. Ponomareva
doaj   +1 more source

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