Results 41 to 50 of about 220,763 (119)

Identifying Hub Genes and miRNAs Associated with Mesial Temporal Lobe Epilepsy

Experimed
Objective: Mesial temporal lobe epilepsy (MTLE) is a form of focal epilepsy. Recent studies indicate that microRNAs (miRNAs) are involved in the pathogenesis of MTLE.
Ömer Faruk Düzenli, Emrah Yücesan, Simay Bozkurt   +2 more
doaj   +1 more source

Exploring the potential relevance of microRNAs targeting the ARVC-related gene interaction network to cancer: an in silico testing hypothesis

Journal of Biological Research - Thessaloniki
Arrhythmogenic Right Ventricular Cardiomyopathy (ARVC) is a genetic disorder of the myocardium. Mutations in the PKP2, DSP, DSG2, DSC2, JUP, TMEM43, PLN and DES genes which encode proteins of the cardiac desmosome have been linked to the disease yet, the
Athanasios Balaskas, Argyris Dallis, Sotirios G Zarogiannis, Chrissi Hatzoglou, Konstantinos I Gourgoulianis, Erasmia Rouka   +5 more
doaj   +1 more source

Identification of Dysregulated Mechanisms and Potential Biomarkers in Ischemic Stroke Onset

International Journal of General Medicine, 2021
Bing Feng,1,* Xinling Meng,2,* Hui Zhou,1,* Liechun Chen,3 Chun Zou,3 Lucong Liang,3 Youshi Meng,3,4 Ning Xu,3,4 Hao Wang,3,4 Donghua Zou3,4 1Department of Neurology, The People’s Hospital of Guiping, Guigang, Guangxi, 537200, People’s ...
Feng B, Meng X, Zhou H, Chen L, Zou C, Liang L, Meng Y, Xu N, Wang H, Zou D   +9 more
doaj  

Systematic review and meta-analysis of dysregulated miRNAs in patients with severe pneumonia

Türk Biyokimya Dergisi
A meta-analysis was conducted to systematically assess the diagnostic efficacy of miRNAs in severe pneumonia, aiming to identify valuable diagnostic markers for this critical condition.
Wang Chunxia, Ye Xuhui, Xu Jinmei, Li Qiaoke, Sun Mingze, Yi Jianping   +5 more
doaj   +1 more source

Bioinformatics Analysis of the miR-15 Family Members and Their Potential Target Genes in Breast Cancer Progression

Advanced Biomedical Research
Background: Breast cancer is the most common cancer in women and the second most frequent cancer worldwide. Changes in miRNA levels are associated with various diseases, including cancer, making them ideal non-invasive biomarkers for diagnosis, prognosis,
Mahdi Alizadeh, Mahdieh Salimi
doaj   +1 more source

Investigating the Effect of Secretome Secreted from Adult Rat Kidney-Derived Stem Cells on the Expression of miR375, miR494 and Tissue Changes in Glycerol-Induced Acute Kidney Injury

Advanced Biomedical Research
Background: Acute kidney injury (AKI) causes high mortality. Cell therapy has provided acceptable results, but factors such as immune rejection and teratoma formation have limited their use. The purpose of this research is to study the reparative effects
Armita Valizadeh Gorji, Fereshtesadat Fakhredini, Fatemeh Soltanpour, Esrafil Mansouri   +3 more
doaj   +1 more source

The Pleiotropic Role of the MicroRNA-17-92 Cluster in Cardiovascular Diseases and Cancer

Reviews in Cardiovascular Medicine
Cardiovascular diseases, including acute myocardial infarctions, heart failure, hypertension, adverse cardiac remodeling, hypertrophy, atherosclerosis, and coronary artery disease, continue to lead to global mortality rates.
Arun Samidurai, Manu Saravanan, Virginia Villani Zwiren, Varun Kodali, Kush Savsani, Nuhash Bhuiyan, Shruti Yerramothu, Suet Ying Valerie Lau, Ena Baral, Sara Hammel, Anindita Das   +10 more
doaj   +1 more source

New Insights into the Roles of Yes-Associated Protein (YAP1) in Colorectal Cancer Development and Progression [PDF]

Iranian Journal of Colorectal Research, 2019
Yes-associated protein (YAP1), the downstream effector of the Hippo pathway, plays important roles in the regulation of tissue reconstruction,stem cell proliferation, and development of different cancers.
Fariba Dehghanian, Zahra Azhir, Atefeh Akbari, Zohreh Hojati   +3 more
doaj  

Screening of serum exosomal miRNAs as diagnostic biomarkers in Alzheimer's disease

陆军军医大学学报
Objective To screen differentially expressed miRNAs (DEMs) by comparing the expression of miRNAs in serum exosomes between Alzheimer's disease (AD) patients and healthy controls.
DUAN Xian, ZHENG Qing, LIANG Lihui
doaj   +1 more source

Remodelling of miRNA Regulatory Landscape During West Nile Virus (WNV) Infection. [PDF]

Epigenomes
De Hayr L, Khromykh AA, Slonchak A.
europepmc   +1 more source