Results 61 to 70 of about 287,756 (317)
A review on miRNAs as new biomarkers for colorectal cancer [PDF]
Journal of Advanced Biomedical Sciences, 2019 Background & Objective: Since colorectal cancer does not often have phenotypic symptoms in the early stages, the study of biomarkers for the diagnosis and prognosis of the tumor is very important.
Kiyanoush Mohammadi, Reza Safaralizadeh
doaj
Molecules, 2019 Inositol hexaphosphate (IP6), a natural dietary component, has been found as an antitumor agent by stimulating apoptosis and inhibiting cancer cell proliferation, their migration, and metastasis in diverse cancers including colon cancer.
Małgorzata Kapral +2 more
doaj +1 more source
European Journal of Biology, 2021 Objective: Despite advances in treatment approaches, metastatic castration-resistant prostate cancer (mCRPC) remains a clinical challenge to treat. Cabazitaxel (Cab), a third-line chemotherapy option for mCRPC, exhibits limited efficiency due to the ...
Işıl Ezgi Eryılmaz +4 more
doaj +1 more source
Role of miRNAs in Legume Crops in Response to Biotic and Abiotic Stress [PDF]
, 2017 Legumes are special group of nitrogen-fixing plants that are an essential component of cropping system and important source of food/feed for human/animal consumption.
Sandeep Kumar +6 more
core +1 more source
Viral miRNAs confer survival in host cells by targeting apoptosis related host genes [PDF]
, 2021 miRNAs are small non-coding RNAs that regulate gene expression by RNA silencing. Like eukaryotic organisms, some viruses also produce miRNAs. While contribution of host miRNA in preventing viral pathogenesis has been studied, how viral miRNA confers ...
Islam, ABMMK, Islam, MS
core +1 more source
Principles of miRNA/miRNA* function in plant MIRNA processing
Nucleic Acids ResearchAbstract MicroRNAs (miRNAs) are essential regulators of gene expression, defined by their unique biogenesis, which requires the precise excision of the small RNA from an imperfect fold-back precursor. Unlike their animal counterparts, plant miRNA precursors exhibit variations in sizes and shapes.
Santiago Rosatti +6 more
openaire +4 more sources
The TATA-box motif and its impact on transcriptional gene regulation by miRNAs
Biomolecular Concepts, 2015 Emerging evidence suggests that components of the small RNAs pathway interact with chromatin to regulate nuclear events, such as gene transcription. However, it has recently been reported that in some cases, gene transcription regulation by cellular ...
Granados-Riveron Javier T. +1 more
doaj +1 more source
Exosomes and miRNAs in disease pathogenesis and opportunities for molecular targeting [PDF]
, 2016 Exosomes/extracellular vesicles (EVs) are cell-derived mixed-populations of vesicles released by almost all cells into the intercellular microenvironment, ending up in the circulation.
Momen Heravi, F.
core +1 more source
Trim25 is an RNA-specific activator of Lin28a/TuT4-mediated uridylation [PDF]
, 2014 RNA binding proteins have thousands of cellular RNA targets and often exhibit opposite or passive molecular functions. Lin28a is a conserved RNA binding protein involved in pluripotency and tumorigenesis that was previously shown to trigger TuT4-mediated
Nowak, Jakub S. +14 more
core +1 more source
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source