Results 61 to 70 of about 221,688 (170)

Circulating microRNAs as biomarker in prostate cancer and their significance in the differentiation of benign and malignant conditions of the prostate

Urology Annals
Background: Prostate cancer is among the most commonly diagnosed cancers in males worldwide. While Prostate-specific antigen (PSA) remains the front-line screening marker, it lacks sufficient diagnostic accuracy. Aims and Objectives: So, in the quest for
Kowsalya Ramprasad, Madhura Navule Siddappa, Manohar Chikkamoga Siddaiah, Manju Moorthy, Gopalakrishna Ramaswamy   +4 more
doaj   +1 more source

Therapeutic Applications of Poly-miRNAs and miRNA Sponges

International Journal of Molecular Sciences
MicroRNAs (miRNAs) are small, non-coding RNA molecules that play crucial roles in regulating gene expression, and their dysregulation is implicated in various human diseases. Over the years, several research groups have identified miRNAs as promising therapeutic targets for intervention. Therapeutic strategies involve either overexpression or knockdown
Miguel Ibáñez-Hernández, Cynthia Avendaño-Portugal, Mariela Montaño-Samaniego, Raquel Guttman-Bazbaz, Diana Marcela Bravo-Estupiñan   +4 more
openaire   +2 more sources

Identification of Dysregulated Mechanisms and Potential Biomarkers in Ischemic Stroke Onset

International Journal of General Medicine, 2021
Bing Feng,1,* Xinling Meng,2,* Hui Zhou,1,* Liechun Chen,3 Chun Zou,3 Lucong Liang,3 Youshi Meng,3,4 Ning Xu,3,4 Hao Wang,3,4 Donghua Zou3,4 1Department of Neurology, The People’s Hospital of Guiping, Guigang, Guangxi, 537200, People’s ...
Feng B, Meng X, Zhou H, Chen L, Zou C, Liang L, Meng Y, Xu N, Wang H, Zou D   +9 more
doaj  

Bioinformatics Analysis of the miR-15 Family Members and Their Potential Target Genes in Breast Cancer Progression

Advanced Biomedical Research
Background: Breast cancer is the most common cancer in women and the second most frequent cancer worldwide. Changes in miRNA levels are associated with various diseases, including cancer, making them ideal non-invasive biomarkers for diagnosis, prognosis,
Mahdi Alizadeh, Mahdieh Salimi
doaj   +1 more source

Investigating the Effect of Secretome Secreted from Adult Rat Kidney-Derived Stem Cells on the Expression of miR375, miR494 and Tissue Changes in Glycerol-Induced Acute Kidney Injury

Advanced Biomedical Research
Background: Acute kidney injury (AKI) causes high mortality. Cell therapy has provided acceptable results, but factors such as immune rejection and teratoma formation have limited their use. The purpose of this research is to study the reparative effects
Armita Valizadeh Gorji, Fereshtesadat Fakhredini, Fatemeh Soltanpour, Esrafil Mansouri   +3 more
doaj   +1 more source

Systematic review and meta-analysis of dysregulated miRNAs in patients with severe pneumonia

Türk Biyokimya Dergisi
A meta-analysis was conducted to systematically assess the diagnostic efficacy of miRNAs in severe pneumonia, aiming to identify valuable diagnostic markers for this critical condition.
Wang Chunxia, Ye Xuhui, Xu Jinmei, Li Qiaoke, Sun Mingze, Yi Jianping   +5 more
doaj   +1 more source

The Pleiotropic Role of the MicroRNA-17-92 Cluster in Cardiovascular Diseases and Cancer

Reviews in Cardiovascular Medicine
Cardiovascular diseases, including acute myocardial infarctions, heart failure, hypertension, adverse cardiac remodeling, hypertrophy, atherosclerosis, and coronary artery disease, continue to lead to global mortality rates.
Arun Samidurai, Manu Saravanan, Virginia Villani Zwiren, Varun Kodali, Kush Savsani, Nuhash Bhuiyan, Shruti Yerramothu, Suet Ying Valerie Lau, Ena Baral, Sara Hammel, Anindita Das   +10 more
doaj   +1 more source

MicroRNA-155 (miRNA-155); miRNA-363* ; miRNA-206; miRNA-494; miRNA-155; miRNA-184; miRNA-542-3p; miRNA-9* [PDF]

Science-Business eXchange, 2009
openaire   +1 more source

New Insights into the Roles of Yes-Associated Protein (YAP1) in Colorectal Cancer Development and Progression [PDF]

Iranian Journal of Colorectal Research, 2019
Yes-associated protein (YAP1), the downstream effector of the Hippo pathway, plays important roles in the regulation of tissue reconstruction,stem cell proliferation, and development of different cancers.
Fariba Dehghanian, Zahra Azhir, Atefeh Akbari, Zohreh Hojati   +3 more
doaj  

Screening of serum exosomal miRNAs as diagnostic biomarkers in Alzheimer's disease

陆军军医大学学报
Objective To screen differentially expressed miRNAs (DEMs) by comparing the expression of miRNAs in serum exosomes between Alzheimer's disease (AD) patients and healthy controls.
DUAN Xian, ZHENG Qing, LIANG Lihui
doaj   +1 more source