Results 51 to 60 of about 221,688 (170)
MiRNAs in aortic aneurysm and dissection: a narrative review [PDF]
Background and Objective: Aortic aneurysm and dissection are serious life-threatening cardiovascular emergencies, and their pathogenesis includes vascular inflammation, extracellular matrix remodeling and matrix metalloproteinases, phenotype switch of ...
Huahua Zhang +5 more
doaj +1 more source
Mechanisms of miRNAs and their expression in gastric cancer [PDF]
Gastric cancer is the fourth most common cancer in the world and the second leading cause of cancer-related deaths worldwide. Gastric cancer was responsible for approximately 768,000 deaths.
Tahereh Eslammanesh +7 more
doaj +1 more source
Profiling of miRNAs in pediatric asthma: Upregulation of miRNA-221 and miRNA-485-3p
The aim of this study was to investigate the expression profiles of microRNAs (miRNAs) in pediatric asthma and to determine candidate miRNAs responsible for the pathogenesis of this disease. Microarrays were used to detect the differences in the miRNA expression levels between asthmatic children and controls. Airway
Feng, Liu +4 more
openaire +3 more sources
miRNA target prediction through mining of miRNA relationships
miRNAs are small regulators that mediate gene expression and each miRNA regulates specific target genes. In animals, target prediction of the miRNAs is accomplished through several computational methods, i.e. miRanda, TargetScan and PicTar.
Zhang, Y., Bruin, J.S. de, Verbeek, F.J.
openaire +2 more sources
Introns of plant pri‐miRNAs enhance miRNA biogenesis
Abstract Plant MIR genes are independent transcription units that encode long primary miRNA precursors, which usually contain introns. For two miRNA genes, MIR163 and MIR161 , we show that ...
Bielewicz, Dawid +7 more
openaire +4 more sources
Sara Cazorla-Rivero,1,2 Glorian Mura-Escorche,1,2 Francisca Gonzalvo-Hernández,3 Delia Mayato,1 Elizabeth Córdoba-Lanús,1,2,4,* Ciro Casanova1– 3,* 1Research Unit, Hospital Universitario Nuestra Señora de Candelaria ...
Cazorla-Rivero S +5 more
doaj
Identifying Hub Genes and miRNAs Associated with Mesial Temporal Lobe Epilepsy
Objective: Mesial temporal lobe epilepsy (MTLE) is a form of focal epilepsy. Recent studies indicate that microRNAs (miRNAs) are involved in the pathogenesis of MTLE.
Ömer Faruk Düzenli +2 more
doaj +1 more source
Replication Stress and Consequential Instability of the Genome and Epigenome
Cells must faithfully duplicate their DNA in the genome to pass their genetic information to the daughter cells. To maintain genomic stability and integrity, double-strand DNA has to be replicated in a strictly regulated manner, ensuring the accuracy of ...
Pawlos S. Tsegay, Yanhao Lai, Yuan Liu
doaj +1 more source
Arrhythmogenic Right Ventricular Cardiomyopathy (ARVC) is a genetic disorder of the myocardium. Mutations in the PKP2, DSP, DSG2, DSC2, JUP, TMEM43, PLN and DES genes which encode proteins of the cardiac desmosome have been linked to the disease yet, the
Athanasios Balaskas +5 more
doaj +1 more source
Zhikang Zhu,1,* Xinge Zhang,1,* Xuran Lin,1 Yuechen Wang,1 Chunmao Han,2,3 Shoujie Wang1,4 1Department of Plastic Surgery, The Fourth Affiliated Hospital of School of Medicine, and International School of Medicine, Zhejiang University, Yiwu ...
Zhu Z +5 more
doaj

