Results 51 to 60 of about 221,688 (170)

MiRNAs in aortic aneurysm and dissection: a narrative review [PDF]

open access: yesExRNA
Background and Objective: Aortic aneurysm and dissection are serious life-threatening cardiovascular emergencies, and their pathogenesis includes vascular inflammation, extracellular matrix remodeling and matrix metalloproteinases, phenotype switch of ...
Huahua Zhang   +5 more
doaj   +1 more source

Mechanisms of miRNAs and their expression in gastric cancer [PDF]

open access: yesArchives of Razi Institute
Gastric cancer is the fourth most common cancer in the world and the second leading cause of cancer-related deaths worldwide. Gastric cancer was responsible for approximately 768,000 deaths.
Tahereh Eslammanesh   +7 more
doaj   +1 more source

Profiling of miRNAs in pediatric asthma: Upregulation of miRNA-221 and miRNA-485-3p

open access: yesMolecular Medicine Reports, 2012
The aim of this study was to investigate the expression profiles of microRNAs (miRNAs) in pediatric asthma and to determine candidate miRNAs responsible for the pathogenesis of this disease. Microarrays were used to detect the differences in the miRNA expression levels between asthmatic children and controls. Airway
Feng, Liu   +4 more
openaire   +3 more sources

miRNA target prediction through mining of miRNA relationships

open access: yes2008 8th IEEE International Conference on BioInformatics and BioEngineering, 2008
miRNAs are small regulators that mediate gene expression and each miRNA regulates specific target genes. In animals, target prediction of the miRNAs is accomplished through several computational methods, i.e. miRanda, TargetScan and PicTar.
Zhang, Y., Bruin, J.S. de, Verbeek, F.J.
openaire   +2 more sources

Introns of plant pri‐miRNAs enhance miRNA biogenesis

open access: yesThe EMBO Reports, 2013
Abstract Plant MIR genes are independent transcription units that encode long primary miRNA precursors, which usually contain introns. For two miRNA genes, MIR163 and MIR161 , we show that ...
Bielewicz, Dawid   +7 more
openaire   +4 more sources

Circulating miR-1246 in the Progression of Chronic Obstructive Pulmonary Disease (COPD) in Patients from the BODE Cohort

open access: yesInternational Journal of COPD, 2020
Sara Cazorla-Rivero,1,2 Glorian Mura-Escorche,1,2 Francisca Gonzalvo-Hernández,3 Delia Mayato,1 Elizabeth Córdoba-Lanús,1,2,4,* Ciro Casanova1– 3,* 1Research Unit, Hospital Universitario Nuestra Señora de Candelaria ...
Cazorla-Rivero S   +5 more
doaj  

Identifying Hub Genes and miRNAs Associated with Mesial Temporal Lobe Epilepsy

open access: yesExperimed
Objective: Mesial temporal lobe epilepsy (MTLE) is a form of focal epilepsy. Recent studies indicate that microRNAs (miRNAs) are involved in the pathogenesis of MTLE.
Ömer Faruk Düzenli   +2 more
doaj   +1 more source

Replication Stress and Consequential Instability of the Genome and Epigenome

open access: yesMolecules, 2019
Cells must faithfully duplicate their DNA in the genome to pass their genetic information to the daughter cells. To maintain genomic stability and integrity, double-strand DNA has to be replicated in a strictly regulated manner, ensuring the accuracy of ...
Pawlos S. Tsegay, Yanhao Lai, Yuan Liu
doaj   +1 more source

Exploring the potential relevance of microRNAs targeting the ARVC-related gene interaction network to cancer: an in silico testing hypothesis

open access: yesJournal of Biological Research - Thessaloniki
Arrhythmogenic Right Ventricular Cardiomyopathy (ARVC) is a genetic disorder of the myocardium. Mutations in the PKP2, DSP, DSG2, DSC2, JUP, TMEM43, PLN and DES genes which encode proteins of the cardiac desmosome have been linked to the disease yet, the
Athanasios Balaskas   +5 more
doaj   +1 more source

Research Advances and Application Progress on miRNAs in Exosomes Derived From M2 Macrophage for Tissue Injury Repairing

open access: yesInternational Journal of Nanomedicine
Zhikang Zhu,1,* Xinge Zhang,1,* Xuran Lin,1 Yuechen Wang,1 Chunmao Han,2,3 Shoujie Wang1,4 1Department of Plastic Surgery, The Fourth Affiliated Hospital of School of Medicine, and International School of Medicine, Zhejiang University, Yiwu ...
Zhu Z   +5 more
doaj  

Home - About - Disclaimer - Privacy