Results 31 to 40 of about 365,273 (304)

Roles of miRNAs in Colorectal Cancer: Therapeutic Implications and Clinical Opportunities [PDF]

Advanced Pharmaceutical Bulletin, 2021
Colorectal cancer (CRC) is one of the most disseminated diseases across the globe engaging the digestive system. Various therapeutic methods from traditional to the state-of-the-art ones have been applied in CRC patients, however, the attempts have been ...
Amir Mehrgou, Shima Ebadollahi, Khaled Seidi, Mohammad Hosein Ayoubi-Joshaghani, Amirhossein Ahmadieh Yazdi, Peyman Zare, Mehdi Jaymand, Rana Jahanban-Esfahlan   +7 more
doaj   +1 more source

microRNA. Diagnostic Perspective [PDF]

, 2015
Biomarkers are biological measures of a biological state. An ideal marker should be safe and easy to measure, cost efficient, modifiable with treatment, and consistent across gender and ethnic groups. To date, none of the available biomarkers satisfy all
FARUQ, MD OMAR, VECCHIONE, ANDREA
core   +2 more sources

Computational and Experimental Tools of miRNAs in Cancer [PDF]

Middle East Journal of Cancer, 2020
MicroRNAs (miRNAs) are short non-protein coding and single-stranded small RNA molecules with a critical role in the regulation of gene expression.
Esen Çakmak
doaj   +1 more source

MicroRNAs in melanoma development and resistance to target therapy [PDF]

, 2017
microRNAs constitute a complex class of pleiotropic post-transcriptional regulators of gene expression involved in the control of several physiologic and pathologic processes.
Ascierto, Paolo Antonio, Ciliberto, Gennaro, Costantini, Susan, Croce, Carlo M, Fattore, Luigi, Malpicci, Debora, Mancini, Rita, Ruggiero, Ciro Francesco   +7 more
core   +1 more source

Using miRNA-Analyzer for the Analysis of miRNA Data [PDF]

Microarrays, 2016
MicroRNAs (miRNAs) are small biological molecules that play an important role during the mechanisms of protein formation. Recent findings have demonstrated that they act as both positive and negative regulators of protein formation. Thus, the investigation of miRNAs, i.e., the determination of their level of expression, has developed a huge interest in
Pietro Guzzi, Giuseppe Tradigo, Pierangelo Veltri   +2 more
openaire   +2 more sources

Down-regulation of the Lamin A/C in neuroblastoma triggers the expansion of tumor initiating cells [PDF]

, 2015
Tumor-initiating cells constitute a population within a tumor mass that shares properties with normal stem cells and is considered responsible for therapy failure in many cancers.
AMENDOLA, Donatella, Bearzi, Claudia, Bucci, Barbara, Camerlingo, Rosalba, CARICO, ELISABETTA, D'Agnano, Igea, DOMINICI, Carlo, Felsani, Armando, Guglielmi, Loredana, Iannetti, Ilaria, Leonetti, Carlo, MARESCA, GIOVANNA, MEGIORNI, Francesca, Mercanti, Delio, MILAN, MARIKA, Musa, Carla, Nardella, Marta, Pirozzi, Giuseppe, Porru, Manuela, Rizzi, Roberto, Sessa, Giuseppe   +20 more
core   +2 more sources

Linc-smad7 promotes myoblast differentiation and muscle regeneration via sponging miR-125b

Epigenetics, 2018
Long noncoding RNAs (lncRNAs) are involved in the regulation of skeletal muscle development. In the present study, differentially expressed lncRNAs were identified from RNA-seq data derived from myoblasts and myotubes.
Chengchuang Song, Jian Wang, Yilei Ma, Zhaoxin Yang, Dong Dong, Hui Li, Jiameng Yang, Yongzhen Huang, Martin Plath, Yun Ma, Hong Chen   +10 more
doaj   +1 more source

Synergic microRNAs suppress human glioblastoma progression by modulating clinically relevant targets

Molecular Therapy: Nucleic Acids
Glioblastoma (GBM) is a highly aggressive brain tumor characterized by therapy-resistant glioma stem-like cells (GSCs) and extensive infiltration into surrounding brain tissue.
Silvia Rancati, Rui C. Pereira, Michele Schlich, Stefania Sgroi, Silvia Beatini, Letizia La Rosa, Lidia Giantomasi, Roberta Pelizzoli, Clarissa Braccia, Andrea Di Fonzo, Carlotta Spattini, Kiril Tuntevski, Amanda Lo Van, Meritxell Pons-Espinal, Annalisa Palange, Adriana Bajetto, Antonio Daga, Andrea Armirotti, Tullio Florio, Paolo Decuzzi, Davide De Pietri Tonelli   +20 more
doaj   +1 more source

Role of Circulating Exosomal miRNA-3976 in Early Diabetic Retinopathy

International Journal of Nanomedicine, 2023
Songtao Yang,1,2 Jiaoyue Zhang,1,2 Tianshu Zeng,1,2 Juan Zheng,1,2 Jie Min,1,2 Lulu Chen1,2 1Department of Endocrinology, Union Hospital, Huazhong University of Science and Technology Tongji Medical College, Wuhan, Hubei, People’s Republic of China ...
Yang S, Zhang J, Zeng T, Zheng J, Min J, Chen L   +5 more
doaj  

Characterization of protein, long noncoding RNA and microRNA signatures in extracellular vesicles derived from resting and degranulated mast cells

Journal of Extracellular Vesicles, 2020
Mast cells (MCs) are known to participate in a variety of patho-physiological processes depending largely on the intragranular mediators and the production of cytokines and chemokines during degranulation. Recently, extracellular vesicles (EVs) have been
Yuting Liang, Sheng Huang, Longwei Qiao, Xia Peng, Chong Li, Kun Lin, Guogang Xie, Jia Li, Lihui Lin, Yue Yin, Huanjin Liao, Qian Li, Li Li   +12 more
doaj   +1 more source