Results 31 to 40 of about 221,688 (170)
Using miRNA-Analyzer for the Analysis of miRNA Data [PDF]
MicroRNAs (miRNAs) are small biological molecules that play an important role during the mechanisms of protein formation. Recent findings have demonstrated that they act as both positive and negative regulators of protein formation. Thus, the investigation of miRNAs, i.e., the determination of their level of expression, has developed a huge interest in
Pietro Guzzi +2 more
openaire +2 more sources
Jingwei Wang,1,2,* Bowen Xia,3,* Ruimin Ma,1 Qiao Ye1,2 1Beijing Institute of Respiratory Medicine, Beijing Chaoyang Hospital, Capital Medical University, Beijing, People’s Republic of China; 2Department of Occupational Medicine and Toxicology ...
Wang J, Xia B, Ma R, Ye Q
doaj
A Collection of Pre-mRNA Splicing Mutants in Arabidopsis thaliana
To investigate factors influencing pre-mRNA splicing in plants, we conducted a forward genetic screen using an alternatively-spliced GFP reporter gene in Arabidopsis thaliana.
Tatsuo Kanno +7 more
doaj +1 more source
Jifeng Yu, Yingmei Li, Yue Pan, Yu Liu, Haizhou Xing, Xinsheng Xie, Dingming Wan, Zhongxing Jiang Department of Hematology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, People’s Republic of ChinaCorrespondence: Jifeng Yu;
Yu J +7 more
doaj
A review on miRNAs as new biomarkers for colorectal cancer [PDF]
Background & Objective: Since colorectal cancer does not often have phenotypic symptoms in the early stages, the study of biomarkers for the diagnosis and prognosis of the tumor is very important.
Kiyanoush Mohammadi, Reza Safaralizadeh
doaj
Inositol hexaphosphate (IP6), a natural dietary component, has been found as an antitumor agent by stimulating apoptosis and inhibiting cancer cell proliferation, their migration, and metastasis in diverse cancers including colon cancer.
Małgorzata Kapral +2 more
doaj +1 more source
Objective: Despite advances in treatment approaches, metastatic castration-resistant prostate cancer (mCRPC) remains a clinical challenge to treat. Cabazitaxel (Cab), a third-line chemotherapy option for mCRPC, exhibits limited efficiency due to the ...
Işıl Ezgi Eryılmaz +4 more
doaj +1 more source
Principles of miRNA/miRNA* function in plant MIRNA processing
Abstract MicroRNAs (miRNAs) are essential regulators of gene expression, defined by their unique biogenesis, which requires the precise excision of the small RNA from an imperfect fold-back precursor. Unlike their animal counterparts, plant miRNA precursors exhibit variations in sizes and shapes.
Santiago Rosatti +6 more
openaire +4 more sources
The TATA-box motif and its impact on transcriptional gene regulation by miRNAs
Emerging evidence suggests that components of the small RNAs pathway interact with chromatin to regulate nuclear events, such as gene transcription. However, it has recently been reported that in some cases, gene transcription regulation by cellular ...
Granados-Riveron Javier T. +1 more
doaj +1 more source
Background/Objectives: Recently, epigenetic mechanisms have been recognized as crucial in atopic dermatitis development. The emphasis of this research was on expanding existing knowledge about the epigenetic aspects of atopic dermatitis, as well as identifying new molecules that could serve as disease biomarkers.
Sanja Jakovljevic +4 more
openaire +2 more sources

