Results 11 to 20 of about 468,820 (359)
Deciphering miRNAs’ Action through miRNA Editing [PDF]
International Journal of Molecular Sciences, 2019 MicroRNAs (miRNAs) are small non-coding RNAs with the capability of modulating gene expression at the post-transcriptional level either by inhibiting messenger RNA (mRNA) translation or by promoting mRNA degradation.
M. Correia de Sousa +4 more
semanticscholar +5 more sources
The Tumor Cytosol miRNAs, Fluid miRNAs and Exosome miRNAs in Lung Cancer [PDF]
Frontiers in Oncology, 2015 The focus of this review is to provide an update on the progress of microRNAs (miRNAs) as potential biomarkers for lung cancer. miRNAs are single-stranded, small noncoding RNAs that regulate gene expression and show tissue-specific signatures ...
Haisheng eXu +11 more
core +6 more sources
Cancers, 2021 Glioblastoma (GB) is one of the most common types of lethal brain tumors. Although several treatment options are available including surgery, along with adjuvant chemo and radiotherapy, the disease has a poor prognosis and patients generally die within 14 months of diagnosis. GB is chemo and radio resistant.
Swalih P. Ahmed +2 more
openaire +3 more sources
Integrative Analysis of miRNA-mRNA and miRNA-miRNA Interactions [PDF]
BioMed Research International, 2014 MicroRNAs (miRNAs) are small, noncoding regulatory molecules. They are involved in many essential biological processes and act by suppressing gene expression. The present work reports an integrative analysis of miRNA-mRNA and miRNA-miRNA interactions and their regulatory patterns using high-throughput miRNA and mRNA datasets. Aberrantly expressed miRNA
Guo, Li +4 more
openaire +2 more sources
Cellular and molecular basis of thyroid autoimmunity
European Thyroid Journal, 2023 Autoimmune thyroid disease (AITD) is the most common human autoimmune disease. The two major clinical manifestations of AITD are Graves’ disease and Hashimoto’s thyroiditis (HT).
Joanna Bogusławska +3 more
doaj +1 more source
miRNAs as Biomarkers in Disease: Latest Findings Regarding Their Role in Diagnosis and Prognosis
Cells, 2020 MicroRNAs (miRNAs) represent a class of small, non-coding RNAs with the main roles of regulating mRNA through its degradation and adjusting protein levels. In recent years, extraordinary progress has been made in terms of identifying the origin and exact
C. Condrat +8 more
semanticscholar +1 more source
Roles of Macrophage Polarization and Macrophage-Derived miRNAs in Pulmonary Fibrosis
Frontiers in Immunology, 2021 This mini-review summarizes the current evidence for the role of macrophage activation and polarization in inflammation and immune response pertinent to interstitial lung disease, specifically pulmonary fibrosis. In the fibrosing lung, the production and
A. Kishore, M. Petrek
semanticscholar +1 more source
Emerging roles of exosomal miRNAs in diabetes mellitus
Clinical and Translational Medicine, 2021 Exosomes are small extracellular vesicles 40–160 nm in diameter that are secreted by almost all cell types. Exosomes can carry diverse cargo including RNA, DNA, lipids, proteins, and metabolites. Exosomes transfer substances and information between cells
Xiaoyun He +3 more
semanticscholar +1 more source
Expression, regulation, and function of exosome‐derived miRNAs in cancer progression and therapy
The FASEB Journal, 2021 Exosomes are a novel class of intercellular signal modulators that contain a wide range of molecules and deliver information between cells and tissues.
Bowen Li, Yu Cao, Mingjun Sun, H. Feng
semanticscholar +1 more source
Biological properties and therapeutic effects of plant-derived nanovesicles
Open Medicine, 2020 Exosomes-like nanoparticles can be released by a variety of plants and vegetables. The relevance of plant-derived nanovesicles (PDNVs) in interspecies communication is derived from their content in biomolecules (lipids, proteins, and miRNAs), absence of ...
Di Gioia Sante +2 more
doaj +1 more source