Results 11 to 20 of about 305,225 (168)

Quantification of miRNAs and Their Networks in the light of Integral Value Transformations [PDF]

, 2011
MicroRNAs (miRNAs) which are on average only 21-25 nucleotides long are key post-transcriptional regulators of gene expression in metazoans and plants.
Pabitra Pal Choudhury, Sk. Sarif Hassan, Arunava Goswami, Arunava Goswami, Vrushali Fangal, Navonil De Sarkar   +5 more
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Unique and conserved MicroRNAs in wheat chromosome 5D revealed by next-generation sequencing [PDF]

, 2013
MicroRNAs are a class of short, non-coding, single-stranded RNAs that act as post-transcriptional regulators in gene expression. miRNA analysis of Triticum aestivum chromosome 5D was performed on 454 GS FLX Titanium sequences of flow sorted chromosome 5D
Hikmet Budak (150694), Melda Kantar, Kurtoglu Kuaybe Yucebilgili, Lucas, Stuart J., Stuart J. Lucas (150688), Stuart J Lucas, Budak, Hikmet, Yucebilgili, Kuaybe, Melda Kantar (402943), Kuaybe Yucebilgili Kurtoglu (436352), Lucas Stuart J., Kantar Melda, Hikmet Budak, Budak Hikmet, Kantar, Melda, Kuaybe Yucebilgili Kurtoglu   +15 more
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Micro RNAs of Epstein-Barr virus promote cell cycle progression and prevent apoptosis of primary human B cells. [PDF]

, 2010
Cellular and viral microRNAs (miRNAs) are involved in many different processes of key importance and more than 10,000 miRNAs have been identified so far.
Seto, Eri, Walz, Nicole, Moosmann Andreas, Hammerschmidt, W., Grömminger, Sebastian, Andreas Moosmann, Wolfgang Hammerschmidt, Adam Grundhoff, Grömminger, S., Hammerschmidt Wolfgang, Grömminger Sebastian, Seto, E., Hammerschmidt, Wolfgang, Grundhoff Adam, Nicole Walz, Walz, N., Grundhoff, A., Moosmann, A., Walz Nicole, Grundhoff, Adam, Sebastian Grömminger, Seto Eri, Moosmann, Andreas, Eri Seto   +23 more
core   +1 more source

Exosome-mediated delivery of gga-miR-20a-5p regulates immune response of chicken macrophages by targeting IFNGR2, MAPK1, MAP3K5, and MAP3K14 [PDF]

Animal Bioscience, 2023
Objective This study aims to evaluate the target genes of gga-miR-20a-5p and the regulated immune responses in the chicken macrophage cell line, HD11, by the exosome-mediated delivery of miR-20a-5p.
Yeojin Hong, Jubi Heo, Suyeon Kang, Thi Hao Vu, Hyun S. Lillehoj, Yeong Ho Hong   +5 more
doaj   +1 more source

Novel network pharmacology methods for drug mechanism of action identification, pre-clinical drug screening and drug repositioning [PDF]

, 2011
The high rates of failure in oncology drug clinical trials highlight the problems of using pre-clinical data to predict the clinical effects of drugs. Here we present two methodology innovations on network pharmacology modeling.
Jianghui Xiong
core   +1 more source

Biological functions and molecular mechanisms of LINC00961 in human cancer

All Life, 2023
Long non-coding RNAs (lncRNAs) are more than 200 bp in length and do not translate into functional proteins. They are involved in inhibiting cell growth, migration, and invasion, and in promoting apoptosis.
Kai Li, Yan-Mei Ji, Jia-Long Guo, Qiang Guo   +3 more
doaj   +1 more source

Bioinformatics Analysis of a Functional ANGPT1 Variant That Interferes with miR-607 and Its Association with Susceptibility and Outcome of Ischemic Stroke in a Han Population

Therapeutics and Clinical Risk Management, 2021
Ai-Nian Chen, Ling-Ling Zhong, Ke-ju Ju, Hua Cao Department of Neurology, The Affiliated Huaian No. 1 People’s Hospital of Nanjing Medical University, Huaian, Jiangsu, People’s Republic of ChinaCorrespondence: Ai-Nian ChenDepartment of Neurology, The ...
Chen AN, Zhong LL, Ju K, Cao H
doaj  

Selective inhibition of microRNA accessibility by RBM38 is required for p53 activity [PDF]

, 2011
MicroRNAs (miRNAs) interact with 3'-untranslated regions of messenger RNAs to restrict expression of most protein-coding genes during normal development and cancer. RNA-binding proteins (RBPs) can control the biogenesis, stability and activity of miRNAs.
Horlings, HM, Agami, R, Manoharan, Vijayalaxmi, Elkon, Ran, Hollingworth, D, Ramos, A, Jelle Wesseling, Melo, CA, Esteller, M, Jernej Ule, Ran Elkon, Manoharan, V, Davalos, V, Horlings, Hugo M., Hugo M. Horlings, Wesseling, Jelle, Manel Esteller, Esteller, Manel, Ule, Jernej, Veronica Davalos, Vijayalaxmi Manoharan, Andres Ramos, Reuven Agami, Dave Hollingworth, Oude Vrielink, J, Léveillé, N, Wesseling, J, Nicolas Léveillé, Joachim Oude Vrielink, Hollingworth, Dave, Agami, Reuven, Ule, J, Melo, Carlos A., Carlos le Sage, Elkon, R, Léveillé, Nicolas, Carlos A. Melo, le Sage, Carlos, le Sage, C, Davalos, Veronica, Oude Vrielink, Joachim, Ramos, Andres   +41 more
core   +1 more source

Effect of citalopram and sertraline on the expression of miRNA- 124, 132, and 16 and their protein targets in patients with depression [PDF]

Iranian Journal of Basic Medical Sciences, 2023
Objective(s): This study aimed to evaluate the effect of SSRIs on the expression of miRNAs and their protein targets.Materials and Methods: In a 100 day open-label study of citalopram (n=25) and sertraline (n=25), levels of miRNA 16, 132, and 124 and ...
Mahnaz Ahmadimanesh, Leila Etemad, Dorsa Morshedi Rad, Mohammad Hossein Ghahremani, Amir Hooshang Mohammadpour, Reza Jafarzadeh-Esfehani, Paul Jowsey, Fatemeh Behdani, Adel Moallem, Mohammad Reza Abbaszadegan   +9 more
doaj   +1 more source

Maternal high fat diet during pregnancy and lactation alters hepatic expression of insulin like growth factor-2 and key microRNAs in the adult offspring [PDF]

, 2009
Background :miRNAs play important roles in the regulation of gene functions. Maternal dietary modifications during pregnancy and gestation have long-term effects on the offspring, but it is not known whether a maternal high fat (HF) diet during pregnancy
Zhang F, Bruce, KD, Zhang J, Didelot, Xavier, Didelot Xavier, Lehnert Hendrik, Zhang, F. (Fang), Ceriello Antonio, Lehnert, Hedrik, Zhang, Fang, Vatish M, Didelot X, Hanson Mark, Byrne, CD, Cagampang, Felino R., Ceriello, Antonio, Vatish, Manu, Byrne, Christopher D., Zhang Junlong, Byrne Christopher D, Didelot, X, Bruce Kimberley D, Hanson M, Ceriello, A, Lehnert, H, Hanson, Mark, Zhang, Junlong, Cagampang Felino R, Zhang Fang, Bruce KD, Zhang, F, Cagampang FR, Cagampang, FR, Byrne C.D., Hanson, M, Vatish Manu, Vatish, M, Hanson, Mark A., Lehnert H, Bruce, Kimberley D., Lehnert, Hendrik, Zhang, J   +41 more
core   +1 more source