Results 11 to 20 of about 221,688 (170)
Frontiers in Bioscience-Scholar, 2022 Prostate cancer is one of the most common and socially significant cancers among men. The aim of this study was to identify significant changes in the expression of exosomal miRNAs associated with an increase in the level of prostate specific antigen in ...
Elena A. Pudova +12 more
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Mitochondrial Quality Control: the Role in Cardiac Injury
Frontiers in Bioscience-Landmark, 2022 The heart is a highly energy-dependent organ, and most of its energy is provided by mitochondrial oxidative phosphorylation. Therefore, maintaining a well-functioning mitochondrial population is of paramount importance for cardiac homeostasis, since ...
Grażyna Sygitowicz, Dariusz Sitkiewicz
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Deciphering miRNAs’ Action through miRNA Editing [PDF]
International Journal of Molecular Sciences, 2019 MicroRNAs (miRNAs) are small non-coding RNAs with the capability of modulating gene expression at the post-transcriptional level either by inhibiting messenger RNA (mRNA) translation or by promoting mRNA degradation. The outcome of a myriad of physiological processes and pathologies, including cancer, cardiovascular and metabolic diseases, relies ...
Correia De Sousa, Marta +4 more
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miRNA biomarkers in colon cancer liver metastasis: a preliminary analysis
结直肠肛门外科, 2022 [Objectives] To identify miRNAs associated with colon cancer liver metastasis and their influences on survival. [Methods] The study compared the miRNAs data sets of primary colon cancer tissues and liver metastasis tissues from colon cancer patients with
Fu Tianhao +8 more
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Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms, 2011 Adenovirus infection has a tremendous impact on the cellular silencing machinery. Adenoviruses express high amounts of non-coding virus associated (VA) RNAs able to saturate key factors of the RNA interference (RNAi) processing pathway, such as Exportin 5 and Dicer. Furthermore, a proportion of VA RNAs is cleaved by Dicer into viral microRNAs (mivaRNAs)
Carnero, Elena +2 more
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Expression of miRNA-451 and miRNA-885 in Meningiomas
In Vivo, 2023 Meningiomas are one of the most common intracranial tumors, accounting for 30% of the tumors of the central nervous system. MicroRNAs (miRNAs) are noncoding RNAs containing approximately 18-22 nucleotides that regulate gene expression by interfering with transcription or inhibiting translation.
Ozgur, Baran +12 more
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The American Journal of Pathology, 2009 Cancer is the result of a complex multistep process that involves the accumulation of sequential alterations of several genes, including those encoding microRNAs (miRNAs). miRNAs are a class of 17- to 27-nucleotide single-stranded RNA molecules that regulate gene expression posttranscriptionally.
Rosa, Visone, Carlo M, Croce
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Exosome-mediated delivery of gga-miR-20a-5p regulates immune response of chicken macrophages by targeting IFNGR2, MAPK1, MAP3K5, and MAP3K14 [PDF]
Animal Bioscience, 2023 Objective This study aims to evaluate the target genes of gga-miR-20a-5p and the regulated immune responses in the chicken macrophage cell line, HD11, by the exosome-mediated delivery of miR-20a-5p.
Yeojin Hong +5 more
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Biological functions and molecular mechanisms of LINC00961 in human cancer
All Life, 2023 Long non-coding RNAs (lncRNAs) are more than 200 bp in length and do not translate into functional proteins. They are involved in inhibiting cell growth, migration, and invasion, and in promoting apoptosis.
Kai Li +3 more
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Therapeutics and Clinical Risk Management, 2021 Ai-Nian Chen, Ling-Ling Zhong, Ke-ju Ju, Hua Cao Department of Neurology, The Affiliated Huaian No. 1 People’s Hospital of Nanjing Medical University, Huaian, Jiangsu, People’s Republic of ChinaCorrespondence: Ai-Nian ChenDepartment of Neurology, The ...
Chen AN, Zhong LL, Ju K, Cao H
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