Results 21 to 30 of about 468,820 (359)

MiR-548d-3p Regulates IL-1β Expression in Human Keratoconic Corneal Fibroblasts under Oxidative Stress

open access: yesTaiyuan Ligong Daxue xuebao, 2021
Oxidative stress and inflammatory factors are closely related to keratoconus. As an important gene expression regulator, MiRNAs participate in the physiological and pathological process of keratoconus.
Sijia WANG   +8 more
doaj   +1 more source

MicroRNAs (miRNAs) and Long Non-Coding RNAs (lncRNAs) as New Tools for Cancer Therapy: First Steps from Bench to Bedside

open access: yesTargeted oncology, 2020
Non-coding RNAs represent a significant proportion of the human genome. After having been considered as ‘junk’ for a long time, non-coding RNAs are now well established as playing important roles in maintaining cellular homeostasis and functions.
M. Ratti   +6 more
semanticscholar   +1 more source

Origins and Mechanisms of miRNAs and siRNAs.

open access: yesCell, 2009
Over the last decade, approximately 20-30 nucleotide RNA molecules have emerged as critical regulators in the expression and function of eukaryotic genomes. Two primary categories of these small RNAs--short interfering RNAs (siRNAs) and microRNAs (miRNAs)
R. Carthew, E. Sontheimer
semanticscholar   +1 more source

THE ALBANIAN FACTOR OF DESTABILIZATION OF THE WESTERN BALKANS: SCENARIO APPROACH

open access: yesVestnik MGIMO-Universiteta, 2018
The Albanian factor of the Balkan policy, which received its first institutional design in the late 19th century – “Prizrenskaya League”, is currently a serious destructor of the situation in the Western Balkans (Albania, Bosnia and Herzegovina (BiH ...
E. G. Ponomareva
doaj   +1 more source

Dynamic Profiling of Exosomal microRNAs in Blood Plasma of Patients with Castration-Resistant Prostate Cancer

open access: yesFrontiers in Bioscience-Scholar, 2022
Prostate cancer is one of the most common and socially significant cancers among men. The aim of this study was to identify significant changes in the expression of exosomal miRNAs associated with an increase in the level of prostate specific antigen in ...
Elena A. Pudova   +12 more
doaj   +1 more source

Expression of miRNA-451 and miRNA-885 in Meningiomas

open access: yesIn Vivo, 2023
Meningiomas are one of the most common intracranial tumors, accounting for 30% of the tumors of the central nervous system. MicroRNAs (miRNAs) are noncoding RNAs containing approximately 18-22 nucleotides that regulate gene expression by interfering with transcription or inhibiting translation.
Ozgur, Baran   +12 more
openaire   +3 more sources

Mitochondrial Quality Control: the Role in Cardiac Injury

open access: yesFrontiers in Bioscience-Landmark, 2022
The heart is a highly energy-dependent organ, and most of its energy is provided by mitochondrial oxidative phosphorylation. Therefore, maintaining a well-functioning mitochondrial population is of paramount importance for cardiac homeostasis, since ...
Grażyna Sygitowicz, Dariusz Sitkiewicz
doaj   +1 more source

Unique and conserved MicroRNAs in wheat chromosome 5D revealed by next-generation sequencing [PDF]

open access: yes, 2013
MicroRNAs are a class of short, non-coding, single-stranded RNAs that act as post-transcriptional regulators in gene expression. miRNA analysis of Triticum aestivum chromosome 5D was performed on 454 GS FLX Titanium sequences of flow sorted chromosome 5D
Hikmet Budak (150694)   +15 more
core   +1 more source

miRNA biomarkers in colon cancer liver metastasis: a preliminary analysis

open access: yes结直肠肛门外科, 2022
[Objectives] To identify miRNAs associated with colon cancer liver metastasis and their influences on survival. [Methods] The study compared the miRNAs data sets of primary colon cancer tissues and liver metastasis tissues from colon cancer patients with
Fu Tianhao   +8 more
doaj   +1 more source

Adenovirus and miRNAs

open access: yesBiochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms, 2011
Adenovirus infection has a tremendous impact on the cellular silencing machinery. Adenoviruses express high amounts of non-coding virus associated (VA) RNAs able to saturate key factors of the RNA interference (RNAi) processing pathway, such as Exportin 5 and Dicer. Furthermore, a proportion of VA RNAs is cleaved by Dicer into viral microRNAs (mivaRNAs)
Carnero, Elena   +2 more
openaire   +2 more sources

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