Roles of miRNAs in Colorectal Cancer: Therapeutic Implications and Clinical Opportunities [PDF]
Advanced Pharmaceutical Bulletin, 2021 Colorectal cancer (CRC) is one of the most disseminated diseases across the globe engaging the digestive system. Various therapeutic methods from traditional to the state-of-the-art ones have been applied in CRC patients, however, the attempts have been ...
Amir Mehrgou +7 more
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Linc-smad7 promotes myoblast differentiation and muscle regeneration via sponging miR-125b
Epigenetics, 2018 Long noncoding RNAs (lncRNAs) are involved in the regulation of skeletal muscle development. In the present study, differentially expressed lncRNAs were identified from RNA-seq data derived from myoblasts and myotubes.
Chengchuang Song +10 more
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Computational and Experimental Tools of miRNAs in Cancer [PDF]
Middle East Journal of Cancer, 2020 MicroRNAs (miRNAs) are short non-protein coding and single-stranded small RNA molecules with a critical role in the regulation of gene expression.
Esen Çakmak
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The type II poly(A)-binding protein PABP-2 is a downstream target of the "let-7" microRNA in the heterochronic pathway of "Caenorhabditis elegans" : mechanisms of microRNA-mediated gene silencing in "Caenorhabditis elegans" [PDF]
, 2012 microRNAs (miRNAs) are a large class of small, non-coding RNAs that post-transcriptionally regulate gene expression in animals, plants and protozoa. miRNAs are genomically encoded and transcribed by RNA polymerase II. Primary transcripts are sequentially
Hurschler, Benjamin
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Synergic microRNAs suppress human glioblastoma progression by modulating clinically relevant targets
Molecular Therapy: Nucleic AcidsGlioblastoma (GBM) is a highly aggressive brain tumor characterized by therapy-resistant glioma stem-like cells (GSCs) and extensive infiltration into surrounding brain tissue.
Silvia Rancati +20 more
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Role of Circulating Exosomal miRNA-3976 in Early Diabetic Retinopathy
International Journal of Nanomedicine, 2023 Songtao Yang,1,2 Jiaoyue Zhang,1,2 Tianshu Zeng,1,2 Juan Zheng,1,2 Jie Min,1,2 Lulu Chen1,2 1Department of Endocrinology, Union Hospital, Huazhong University of Science and Technology Tongji Medical College, Wuhan, Hubei, People’s Republic of China ...
Yang S +5 more
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Journal of Extracellular Vesicles, 2020 Mast cells (MCs) are known to participate in a variety of patho-physiological processes depending largely on the intragranular mediators and the production of cytokines and chemokines during degranulation. Recently, extracellular vesicles (EVs) have been
Yuting Liang +12 more
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Mechanisms of microRNA mediated gene silencing in C. elegans [PDF]
, 2009 Mechanisms of microRNA mediated gene silencing in C. elegans Xavier Ding Dissertation abstract microRNAs (miRNAs) are a large family of small non-coding RNAs, which post-transcriptionally repress numerous genes; a type of regulation which is ...
Ding, Xavier
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Bioinformatics analysis of the interaction of miRNAs and piRNAs with human mRNA genes having di- and Trinucleotide repeats [PDF]
, 2022 The variability of nucleotide repeats is considered one of the causes of diseases, but their biological function is not understood. In recent years, the interaction of miRNAs and piRNAs with the mRNAs of genes responsible for developing neurodegenerative
Jainakbayev, Nurlan +8 more
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International Journal of COPD, 2022 Hannah E O’Farrell, Rayleen V Bowman, Kwun M Fong, Ian A Yang Faculty of Medicine, the University of Queensland, Brisbane, QLD, AustraliaCorrespondence: Hannah E O’Farrell, Faculty of Medicine, the University of Queensland, Brisbane, QLD, Australia, Tel +
O'Farrell HE +3 more
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