Results 21 to 30 of about 365,273 (304)

The miRNAome of the postpartum dairy cow liver in negative energy balance [PDF]

, 2014
peer-reviewedBackground: Negative energy balance (NEB) is an altered metabolic state in high yielding cows that occurs during the first few weeks postpartum when energy demands for lactation and maintenance exceed the energy supply from dietary ...
Fatima, Attia, Lynn, David J, Morris, Dermot G., O'Boyle, Padraic, Seoighe, Cathal   +4 more
core   +2 more sources

MiRNAs as novel adipokines : obesity-related circulating MiRNAs influence chemosensitivity in cancer patients [PDF]

, 2020
Adipose tissue is an endocrine organ, capable of regulating distant physiological processes in other tissues via the release of adipokines into the bloodstream.
Dewhurst, T, Hammond, CJ, Topham, CH, Withers, SB   +3 more
core   +2 more sources

Adenovirus and miRNAs

Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms, 2011
Adenovirus infection has a tremendous impact on the cellular silencing machinery. Adenoviruses express high amounts of non-coding virus associated (VA) RNAs able to saturate key factors of the RNA interference (RNAi) processing pathway, such as Exportin 5 and Dicer. Furthermore, a proportion of VA RNAs is cleaved by Dicer into viral microRNAs (mivaRNAs)
Carnero, Elena, Sutherland, James D., Fortes, Puri   +2 more
openaire   +2 more sources

MiRNAs and Cancer [PDF]

The American Journal of Pathology, 2009
Cancer is the result of a complex multistep process that involves the accumulation of sequential alterations of several genes, including those encoding microRNAs (miRNAs). miRNAs are a class of 17- to 27-nucleotide single-stranded RNA molecules that regulate gene expression posttranscriptionally.
Rosa, Visone, Carlo M, Croce
openaire   +2 more sources

Alterations in hepatic miRNA expression during negative energy balance in postpartum dairy cattle [PDF]

, 2014
peer-reviewedBackground Negative energy balance (NEB), an altered metabolic state, occurs in early postpartum dairy cattle when energy demands to support lactation exceed energy intake.
Fatima, Attia, Morris, Dermot G., O'Boyle, Padraig, Seoighe, Cathal, Waters, Sinead M.   +4 more
core   +1 more source

Biological functions and molecular mechanisms of LINC00961 in human cancer

All Life, 2023
Long non-coding RNAs (lncRNAs) are more than 200 bp in length and do not translate into functional proteins. They are involved in inhibiting cell growth, migration, and invasion, and in promoting apoptosis.
Kai Li, Yan-Mei Ji, Jia-Long Guo, Qiang Guo   +3 more
doaj   +1 more source

Serum microRNA array analysis identifies miR-140-3p, miR-33b-3p and miR-671-3p as potential osteoarthritis biomarkers involved in metabolic processes. [PDF]

, 2017
Background: MicroRNAs (miRNAs) in circulation have emerged as promising biomarkers. In this study, we aimed to identify a circulating miRNA signature for osteoarthritis (OA) patients and in combination with bioinformatics analysis to evaluate the utility
A Brazma, A Nan, A Okuhara, A Turchinovich, B Aryal, B Mayr, B Sharif, B Zhang, BM Bolstad, BM Kuhn, BM Mayr, C Beyer, C Chen, C Guay, C Taurino, CL Andersen, D Dlouha, D Iliopoulos, D Zhang, DT Felson, F Kostopoulou, FE Nicolas, G Dennis Jr, G Li, G Tardif, GD Miles, GR Sondag, GS Lien, H Causton, JB van Meurs, JD Storey, JD Storey, KC Vickers, L Qi, M Cross, M Parrizas, MB Goldring, MC Hochberg, MD Paraskevopoulou, MP Gantier, OF Laterza, Q Zhuo, R Gernapudi, RF Loeser, RI Gregory, S Kluzek, S Kumar, S Miyaki, T Thomou, TA Karlsen, VM Borgonio Cuadra, W Cleveland, WM Reichmann, X Chen, X Chen, X Tan, X Wang, Y Klipper-Aurbach, Y Zhang, YH Li   +59 more
core   +2 more sources

Bioinformatics Analysis of a Functional ANGPT1 Variant That Interferes with miR-607 and Its Association with Susceptibility and Outcome of Ischemic Stroke in a Han Population

Therapeutics and Clinical Risk Management, 2021
Ai-Nian Chen, Ling-Ling Zhong, Ke-ju Ju, Hua Cao Department of Neurology, The Affiliated Huaian No. 1 People’s Hospital of Nanjing Medical University, Huaian, Jiangsu, People’s Republic of ChinaCorrespondence: Ai-Nian ChenDepartment of Neurology, The ...
Chen AN, Zhong LL, Ju K, Cao H
doaj  

Effect of citalopram and sertraline on the expression of miRNA- 124, 132, and 16 and their protein targets in patients with depression [PDF]

Iranian Journal of Basic Medical Sciences, 2023
Objective(s): This study aimed to evaluate the effect of SSRIs on the expression of miRNAs and their protein targets.Materials and Methods: In a 100 day open-label study of citalopram (n=25) and sertraline (n=25), levels of miRNA 16, 132, and 124 and ...
Mahnaz Ahmadimanesh, Leila Etemad, Dorsa Morshedi Rad, Mohammad Hossein Ghahremani, Amir Hooshang Mohammadpour, Reza Jafarzadeh-Esfehani, Paul Jowsey, Fatemeh Behdani, Adel Moallem, Mohammad Reza Abbaszadegan   +9 more
doaj   +1 more source

MiRNAs and miRNA Polymorphisms Modify Drug Response [PDF]

International Journal of Environmental Research and Public Health, 2016
Differences in expression of drug response-related genes contribute to inter-individual variation in drugs’ biological effects. MicroRNAs (miRNAs) are small noncoding RNAs emerging as new players in epigenetic regulation of gene expression at post-transcriptional level.
Li, Mu-Peng, Hu, Yao-Dong, Hu, Xiao-Lei, Zhang, Yan-Jiao, Yang, Yong-Long, Jiang, Chun, Tang, Jie, Chen, Xiao-Ping   +7 more
openaire   +2 more sources