Results 21 to 30 of about 221,688 (170)

Effect of citalopram and sertraline on the expression of miRNA- 124, 132, and 16 and their protein targets in patients with depression [PDF]

Iranian Journal of Basic Medical Sciences, 2023
Objective(s): This study aimed to evaluate the effect of SSRIs on the expression of miRNAs and their protein targets.Materials and Methods: In a 100 day open-label study of citalopram (n=25) and sertraline (n=25), levels of miRNA 16, 132, and 124 and ...
Mahnaz Ahmadimanesh, Leila Etemad, Dorsa Morshedi Rad, Mohammad Hossein Ghahremani, Amir Hooshang Mohammadpour, Reza Jafarzadeh-Esfehani, Paul Jowsey, Fatemeh Behdani, Adel Moallem, Mohammad Reza Abbaszadegan   +9 more
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Roles of miRNAs in Colorectal Cancer: Therapeutic Implications and Clinical Opportunities [PDF]

Advanced Pharmaceutical Bulletin, 2021
Colorectal cancer (CRC) is one of the most disseminated diseases across the globe engaging the digestive system. Various therapeutic methods from traditional to the state-of-the-art ones have been applied in CRC patients, however, the attempts have been ...
Amir Mehrgou, Shima Ebadollahi, Khaled Seidi, Mohammad Hosein Ayoubi-Joshaghani, Amirhossein Ahmadieh Yazdi, Peyman Zare, Mehdi Jaymand, Rana Jahanban-Esfahlan   +7 more
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Involvement of plasma miRNAs, muscle miRNAs and mitochondrial miRNAs in the pathophysiology of frailty

Experimental Gerontology, 2019
Frailty is a geriatric syndrome that leads not only to the loss of physical functions, but also to a generalized decline of the organism and a high risk of disability and dependency. Frailty's detection and management represent important goals for current gerontology.
Iryna, Rusanova, José, Fernández-Martínez, Marisol, Fernández-Ortiz, Paula, Aranda-Martínez, Germaine, Escames, Francisco J, García-García, Leocadio, Mañas, Darío, Acuña-Castroviejo   +7 more
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Linc-smad7 promotes myoblast differentiation and muscle regeneration via sponging miR-125b

Epigenetics, 2018
Long noncoding RNAs (lncRNAs) are involved in the regulation of skeletal muscle development. In the present study, differentially expressed lncRNAs were identified from RNA-seq data derived from myoblasts and myotubes.
Chengchuang Song, Jian Wang, Yilei Ma, Zhaoxin Yang, Dong Dong, Hui Li, Jiameng Yang, Yongzhen Huang, Martin Plath, Yun Ma, Hong Chen   +10 more
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Computational and Experimental Tools of miRNAs in Cancer [PDF]

Middle East Journal of Cancer, 2020
MicroRNAs (miRNAs) are short non-protein coding and single-stranded small RNA molecules with a critical role in the regulation of gene expression.
Esen Çakmak
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MiRNAs and miRNA Polymorphisms Modify Drug Response [PDF]

International Journal of Environmental Research and Public Health, 2016
Differences in expression of drug response-related genes contribute to inter-individual variation in drugs’ biological effects. MicroRNAs (miRNAs) are small noncoding RNAs emerging as new players in epigenetic regulation of gene expression at post-transcriptional level.
Li, Mu-Peng, Hu, Yao-Dong, Hu, Xiao-Lei, Zhang, Yan-Jiao, Yang, Yong-Long, Jiang, Chun, Tang, Jie, Chen, Xiao-Ping   +7 more
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Synergic microRNAs suppress human glioblastoma progression by modulating clinically relevant targets

Molecular Therapy: Nucleic Acids
Glioblastoma (GBM) is a highly aggressive brain tumor characterized by therapy-resistant glioma stem-like cells (GSCs) and extensive infiltration into surrounding brain tissue.
Silvia Rancati, Rui C. Pereira, Michele Schlich, Stefania Sgroi, Silvia Beatini, Letizia La Rosa, Lidia Giantomasi, Roberta Pelizzoli, Clarissa Braccia, Andrea Di Fonzo, Carlotta Spattini, Kiril Tuntevski, Amanda Lo Van, Meritxell Pons-Espinal, Annalisa Palange, Adriana Bajetto, Antonio Daga, Andrea Armirotti, Tullio Florio, Paolo Decuzzi, Davide De Pietri Tonelli   +20 more
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Role of Circulating Exosomal miRNA-3976 in Early Diabetic Retinopathy

International Journal of Nanomedicine, 2023
Songtao Yang,1,2 Jiaoyue Zhang,1,2 Tianshu Zeng,1,2 Juan Zheng,1,2 Jie Min,1,2 Lulu Chen1,2 1Department of Endocrinology, Union Hospital, Huazhong University of Science and Technology Tongji Medical College, Wuhan, Hubei, People’s Republic of China ...
Yang S, Zhang J, Zeng T, Zheng J, Min J, Chen L   +5 more
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Characterization of protein, long noncoding RNA and microRNA signatures in extracellular vesicles derived from resting and degranulated mast cells

Journal of Extracellular Vesicles, 2020
Mast cells (MCs) are known to participate in a variety of patho-physiological processes depending largely on the intragranular mediators and the production of cytokines and chemokines during degranulation. Recently, extracellular vesicles (EVs) have been
Yuting Liang, Sheng Huang, Longwei Qiao, Xia Peng, Chong Li, Kun Lin, Guogang Xie, Jia Li, Lihui Lin, Yue Yin, Huanjin Liao, Qian Li, Li Li   +12 more
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Plasma Extracellular Vesicle miRNA Profiles Distinguish Chronic Obstructive Pulmonary Disease Exacerbations and Disease Severity

International Journal of COPD, 2022
Hannah E O’Farrell, Rayleen V Bowman, Kwun M Fong, Ian A Yang Faculty of Medicine, the University of Queensland, Brisbane, QLD, AustraliaCorrespondence: Hannah E O’Farrell, Faculty of Medicine, the University of Queensland, Brisbane, QLD, Australia, Tel +
O'Farrell HE, Bowman RV, Fong KM, Yang IA   +3 more
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