Results 11 to 20 of about 31,091 (262)

From circRNAs to fusion circRNAs in hematological malignancies [PDF]

JCI Insight, 2021
Circular RNAs (circRNAs) represent a type of endogenous noncoding RNA generated by back-splicing events. Unlike the majority of RNAs, circRNAs are covalently closed, without a 5′ end or a 3′ poly(A) tail.
Loelia Babin, Elissa Andraos, Steffen Fuchs, Stéphane Pyronnet, Erika Brunet, Fabienne Meggetto   +5 more
doaj   +5 more sources

Translation of CircRNAs [PDF]

Molecular Cell, 2017
Circular RNAs (circRNAs) are abundant and evolutionarily conserved RNAs of largely unknown function. Here, we show that a subset of circRNAs is translated in vivo.
Nikolaus Rajewsky, Ramberger, E., Ruhe, L., Larissa Ruhe, Dittmar, G., Moshe Samson, Marina Chekulaeva, Stottmeister, C., Daniel Perez-Hernandez, Rajewsky, N., Mor Hanan, Wyler, E., Chekulaeva, M., Ashwal-Fluss, R., Markus Landthaler, Jens, M., Christin Stottmeister, Osnat Bartok, Gunnar Dittmar, Marvin Jens, Bartok, O., Pamudurti, N.R., Landthaler, M., Hanan, M., Sebastian Kadener, Perez-Hernandez, D., Nagarjuna Reddy Pamudurti, Shlomo Shenzis, Reut Ashwal-Fluss, Emanuel Wyler, Evelyn Ramberger, Kadener, S., Shenzis, S., Samson, M.   +33 more
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CircRNAs in Tumor Radioresistance

Biomolecules, 2022
Circular RNAs (circRNAs) are endogenous, non-coding RNAs, which are derived from host genes that are present in several species and can be involved in the progression of various diseases. circRNAs’ leading role is to act as RNA sponges.
Yining Gao, Sitong Huo, Zhou, Qi, Gao, Jiawen, Wang, Ting, Wu, Jiefang, Jiefang Wu, Jiawen Gao, Huo, Sitong, Gao, Yining, Qi Zhou, Chao Zhang, Zhang, Chao, Ting Wang, Lin, Fei, Fei Lin   +15 more
core   +4 more sources

CircRNAs and Fusion-circRNAs in cancer: New players in an old game [PDF]

Cellular Signalling, 2020
Circular RNAs (circRNAs) are generated from 'back-splicing' events. Their circular structure makes them stable in cells and body fluids. These entities are involved in several human diseases including cancer, as they affect the expression of genes ...
Visci G., Macchia G., Storlazzi C. T., Traversa D., Tolomeo D., Agostini A.   +5 more
core   +4 more sources

The role of circRNAs in cancers [PDF]

Bioscience Reports, 2017
Circular RNAs (circRNAs) are recently regarded as a naturally forming family of widespread and diverse endogenous noncoding RNAs (ncRNAs) that may regulate gene expression in mammals.
Jin-Hai Tang, Jian Li, Jian-Hua Zhao, Jia-Hua Hu, Jun-Chen Hou, Xiu Chen, Si-Ying Zhou, He-Da Zhang, Yun-Jie He, Ling-Ping Zhu, Su-Jin Yang, Shan-Liang Zhong   +11 more
core   +3 more sources

CircRNAs in Plants

, 2018
International audienceCircular RNAs (circRNAs) are covalently closed, single-stranded transcripts that are ubiquitously expressed in all eukaryotes and even prokaryotic archaea.
Lai, Xuelei, Conn, Simon,, Bazin, Jérémie, Martin Crespi, Jérémie Bazin, Webb, Stuart, Chloe Zubieta, Xuelei Lai, Simon J. Conn, Crespi, Martin, Stuart Webb, Conn, Simon, J., Zubieta, Chloe   +12 more
core   +4 more sources

Diagnostic and Prognostic Value of Circulating CircRNAs in Cancer

Frontiers in Medicine, 2021
Cancer has been regarded as one of the leading causes of mortality worldwide. Diagnostic and prognostic biomarkers with high sensitivity and specificity for cancer play a crucial role in preventing or treating cancer. Circular RNAs (circRNAs), which hold
Mina Wang, Mina Wang, Feiyu Xie, Feiyu Xie, Jiaran Lin, Jiaran Lin, Yihan Zhao, Qian Zhang, Zehuan Liao, Zehuan Liao, Peng Wei   +10 more
doaj   +2 more sources

Characterization of Immune-Related circRNAs and mRNAs in Human Chronic Atrophic Gastritis

Journal of Inflammation Research
Yang Chao,1 Xiya Jin,1 Rui Guo,2 Hongyu Zhang,2 Xueling Cui,3 Yan Qi2 1Department of Gastroendoscopy, China-Japan Union Hospital of Jilin University, Changchun, Jilin, People’s Republic of China; 2Department of Immunology, College of Basic Medical ...
Chao Y, Jin X, Guo R, Zhang H, Cui X, Qi Y   +5 more
doaj   +2 more sources

CircRNA May Not Be “Circular” [PDF]

Frontiers in Genetics, 2021
Circular RNA (circRNA) is a novel regulatory non-coding RNA and participates in diverse physiological and pathological processes. However, the structures and molecular mechanisms of circRNAs remain unclear. In this study, taking advantage of openly databases and bioinformatics analysis, we observed lots of internal complementary base-pairing sequences (
Handong Sun, Zijuan Wu, Zijuan Wu, Zijuan Wu, Ming Liu, Liang Yu, Liang Yu, Jianyong Li, Jianyong Li, Jianyong Li, Jinwen Zhang, Xiangming Ding, Hui Jin, Hui Jin, Hui Jin   +14 more
openaire   +3 more sources

CircRNA Role and circRNA-Dependent Network (ceRNET) in Asthenozoospermia [PDF]

Frontiers in Endocrinology, 2020
The role of circRNA in reproduction is under investigation. CircRNAs are expressed in human testis, spermatozoa (SPZ), and seminal plasma. Their involvement in embryo development has also been suggested. Asthenozoospermia, a common cause of male infertility, is characterized by reduced or absent sperm motility in fresh ejaculate.
Francesco Manfrevola, Teresa Chioccarelli, Gilda Cobellis, Silvia Fasano, Bruno Ferraro, Carolina Sellitto, Giovanni Marella, Riccardo Pierantoni, Rosanna Chianese   +8 more
openaire   +3 more sources