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Circulating Tumor Cells (CTCs) in Malignant Pleural Mesothelioma (MPM)

Annals of Surgical Oncology, 2013
To investigate the diagnostic and prognostic value of circulating tumor cells (CTCs), a potential surrogate of micrometastasis, in malignant pleural mesothelioma (MPM).We prospectively evaluated CTCs in 7.5 mL of peripheral blood sampled from patients with a suspicion of MPM.
Kazue, Yoneda   +14 more
openaire   +2 more sources

Circulating tumor cells (CTCs) in systemic prostate cancer.

Journal of Clinical Oncology, 2015
e22019 Background: The purpose of the study was to evaluate quantitatively CTCs in peripheral blood of patients with stage III-IV prostate cancer.
Dmitry Aleksandrovich Shvyrev   +10 more
openaire   +1 more source

Circulating tumor cells (CTC) detection: Clinical impact and future directions

Cancer Letters, 2007
Recent molecular and clinical studies have shown that invasion may occur very early in tumor development, thus emphasizing the potential importance of specific and sensitive detection of circulating tumor cells (CTC) and circulating tumor microemboli (CTM).
Patrizia, Paterlini-Brechot   +1 more
openaire   +2 more sources

Microchip for Immunomagnetic Sorting of Circulating Tumor Cells (CTCs)

Circulating tumor cells (CTCs) isolated directly from whole blood opens new perspectives for cancer monitoring and the development of personalized treatments. However, due to their rarity among the multitude of blood cells, it remains a challenge to recover them alive with high level of purity, i.e., with few remaining white blood cells, and in a time ...
Descamps, Lucie   +5 more
openaire   +3 more sources

Current Methods of the Circulating Tumor Cells (CTC) Analysis: A Brief Overview

Current Pharmaceutical Design, 2017
This mini review provides a short overview of the main methods of the selection and analysis of the circulating tumor cells. We briefly focus on the evolution of the technical approaches used in the CTCs analysis from early description of the most discussed contemporary workflows such as Cellsearch and CTC-iChip.
Dementeva, N.   +2 more
openaire   +3 more sources

Experience of detection of circulating tumor cells (CTCs) in patients with epithelial tumors.

Journal of Clinical Oncology, 2015
e22017 Background: The purpose of this study was to analyze the content and detection rate of CTCs in blood of patients with kidney, prostate, breast, lung and colon cancers.
Inna Arnoldovna Novikova   +8 more
openaire   +1 more source

Circulating Tumor Cells (CTCs) as a Liquid Biopsy Material and Drug Target

Current Drug Targets, 2014
Neuro-hormonal regulation of cardiac function via cathecol-amines results in increased heart rate and contractility. A persistent adrenergic tone, however, is an insult to the heart, affecting its regular homeostasis, altering morphology and gene expression patterns, as well as inducing apoptosis of cardio-myocytes. At the same time as being the main
Liang-Liang, Cai   +4 more
openaire   +2 more sources

Abstract 1553: Redefining CTCs: Detection of cytokeratin-negative circulating tumor cells (CTCs)

Cancer Research, 2011
Abstract Introduction: There is growing evidence that CTCs display an epithelial-mesenchymal transition phenotype. Current enrichment techniques rely upon epithelial markers for capture (anti-EpCAM antibodies and cytokeratin [CK]) and may miss important populations of circulating tumor cells.
Chad V. Pecot   +15 more
openaire   +1 more source

Circulating tumor cells (CTC) in small cell lung cancer (SCLC), a promising prognostic factor.

Journal of Clinical Oncology, 2010
7630 Background: Prognostic models for SCLC are using performance score (PS), laboratory tests or disease stage assessed by imaging tests.
Hiltermann, T.N.J.   +8 more
openaire   +3 more sources

The Mechanism of Circulating Tumor Cell (CTC) Detection

MedScien
The high lethality of cancer is mainly attributed to its metastatic ability. Circulating tumor cells (CTCs), as important mediators driving tumor metastasis, have significant research value in tumor progression and prognosis assessment. In recent years, CTC detection methods have been continuously evolving, mainly including detection based on cell ...
openaire   +1 more source

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