Results 161 to 170 of about 4,739,711 (293)

Targeting the KCNC3‐Dependent Anterior Insular‐Lateral Orbitofrontal Cortex Glutamatergic Circuit Attenuates Post‐Traumatic Anxiety

open access: yesAdvanced Science, EarlyView.
Frontal lobe traumatic brain injury is associated with hyperactivity of an insular–orbitofrontal circuit in both patients and mice. By combination of integrating functional imaging, cell‐type–specific circuit manipulation, single‐cell transcriptomics, and whole‐cell recordings, this work identifies the downregulation of the potassium channel KCNC3 in ...
Meng‐Ge Li   +10 more
wiley   +1 more source

Geophysical Fluid Dynamics Laboratory Gallery

open access: yes
Offered by the Geophysical Fluid Dynamics Laboratory (GFDL), the GFDL Gallery is a collection of visualizations which have been prepared in the course of GFDL's research, and subsequently presented at meetings and in the media.

core  

YAP1‐Driven Pathogenic Fibro‐Adipogenic Progenitors Secrete IL‐6 and FGF21 to Mediate Muscle‐Bone Crosstalk and Promote Bone Loss

open access: yesAdvanced Science, EarlyView.
Fibro‐adipogenic progenitors (FAPs) in atrophic muscle undergo YAP1‐driven pathogenic activation, secreting IL‐6 and FGF21 as bone‐catabolic myokines that mediate muscle‐bone crosstalk and promote bone loss. Genetic or pharmacological targeting of this YAP1‐FAP‐myokine axis rescues skeletal deterioration, identifying FAP‐derived myokines as therapeutic
Xiaoyu Cai   +16 more
wiley   +1 more source

Parallel computational fluid dynamics : implementations and results using parallel computers : proceedings of the Parallel CFD '95 Conference, Pasadena, CA, U.S.A., 26-29 June, 1995 /

open access: yes, 1996
Parallel Computational Fluid Dynamics(CFD) is an internationally recognised fast-growing field. Since 1989, the number of participants attending Parallel CFD Conferences has doubled. In order to keep track of current global developments, the Parallel CFD
Parallel CFD Conference(1995 :Pasadena, Calif.)   +1 more
core  

A Multidisciplinary Approach to Patient-Specific Surgical Planning in Congenital Heart Disease∗

open access: yesJACC: Advances
Rachel D. Vanderlaan, MD, PhD   +2 more
doaj   +1 more source

DYNAMIC STUDY ON CEREBROSPINAL FLUID CIRCULATION AFTER SUBARACHNOID HEMORRHAGE

open access: yesDYNAMIC STUDY ON CEREBROSPINAL FLUID CIRCULATION AFTER SUBARACHNOID HEMORRHAGE
Alterations in the cerebrospinal fluid (CSF) circulation after subarachnoid hemorrhage (SAH) were examined in 19 patients. Sources of hemorrhage were aneurysm in 17 cases, arteriovenous aneurysm in one and unknown in one. Cistenography was performed using 1 mCi of 169Yb diethyltriaminepentaacetic acid which was given intrathecally by lumbar injection ...
openaire   +1 more source

Dual Lineages of Langerhans Cells Cooperate to Restore the Immune Barrier after Skin Injury

open access: yesAdvanced Science, EarlyView.
After skin injury, the epidermal immune barrier is rebuilt by two sources of Langerhans cells. Resident Langerhans cells first move into the wound during re‐epithelialization, guided by CXCR2 signaling. Later, recruited monocytes become long‐lived Langerhans cells.
Axel D. Schmitter‐Sánchez   +8 more
wiley   +1 more source

Mixing induced in a dense current flowing down a sloping bottom in a rotating fluid

open access: yes, 2005
A density driven current was generated in the laboratory by releasing dense fluid over a sloping bottom in a rotating freshwater system. Over a wide range of parameter values, the following four flow types were found: laminar, wave, turbulent and eddy ...
ADDUCE, Claudia   +2 more
core  

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