Results 191 to 200 of about 45,939 (308)

Tumor‐Derived Exosomes Deliver Membrane‐Bound Fgl2 to Activate FcγRIIB‐Mediated Immunosuppression in Myeloid‐Derived Suppressor Cells

Advanced Science, EarlyView.
This study reveals that the Fgl2‐FcγRIIB signaling axis is a key mechanism by which MDSCs mediate tumor immune evasion. Tumor‐derived exosomes systemically activate MDSCs via this pathway, positioning this axis as a promising broad‐spectrum target for cancer immunotherapy.
Fenglin Lin, Dingqin Cai, Chunli Jian, Yaxian Qi, Linpeng Zheng, Qiao Yang, Longyao Zhang, Diangang Chen, Lingchen Li, Ping Cai, Lingyou Sun, Luping Zhang, Jianguo Sun   +12 more
wiley   +1 more source

CFD Modelling Validated by PIV of Hydrodynamics in a Raceway Bioreactor: Dead Zone Detection and Flow Field Analysis. [PDF]

Bioengineering (Basel)
Zamora-Campos LA, Rivera-Arreola DE, Rojas-Hernández R, Trujillo-Mora V, Márquez-Vera MA, Salgado-Ramírez JC, Cadena-Ramírez A.   +6 more
europepmc   +1 more source

DYNAMIC STUDY ON CEREBROSPINAL FLUID CIRCULATION AFTER SUBARACHNOID HEMORRHAGE

DYNAMIC STUDY ON CEREBROSPINAL FLUID CIRCULATION AFTER SUBARACHNOID HEMORRHAGE
Alterations in the cerebrospinal fluid (CSF) circulation after subarachnoid hemorrhage (SAH) were examined in 19 patients. Sources of hemorrhage were aneurysm in 17 cases, arteriovenous aneurysm in one and unknown in one. Cistenography was performed using 1 mCi of 169Yb diethyltriaminepentaacetic acid which was given intrathecally by lumbar injection ...
openaire  

Leveraging Artificial Intelligence and Large Language Models for Cancer Immunotherapy

Advanced Science, EarlyView.
Cancer immunotherapy faces challenges in predicting treatment responses and understanding resistance mechanisms. Artificial intelligence (AI) and machine learning (ML) offer powerful solutions for cancer immunotherapy in patient stratification, biomarker discovery, treatment strategy optimization, and foundation model development.
Xinchao Wu, Mengtao Sun, Lusheng Li, Jieqiong Wang, Shibiao Wan   +4 more
wiley   +1 more source

DYNAMIC STUDY ON CEREBROSPINAL FLUID CIRCULATION AFTER SUBARACHNOID HEMORRHAGE

THE BULLETIN OF TOKYO MEDICAL AND DENTAL UNIVERSITY, 1973
HIRATSUKA, Hideo, TSUYUMU, Matsutaira, OHATA, Masahiro, SUGANUMA, Yasuo, FUKUSHIMA, Yoshiharu, INABA, Yutaka   +5 more
openaire   +3 more sources

The ovulation trigger method affects gonadotropin concentrations and gonadotropin receptor expression during final oocyte maturation in women. [PDF]

Front Endocrinol (Lausanne)
Poulsen LC, Johannsen ML, Grøndahl ML, Wissing ML, Yding Andersen C.   +4 more
europepmc   +1 more source

Miniaturized Bidirectional Thermal Stimulation System Integrated With an Electrode Array for Recording Neural Activities

Advanced Science, EarlyView.
This study presents a miniaturized bidirectional thermal stimulation system integrated with an electrode array enabling real‐time, bidirectional modulation and simultaneous recording of neural activity through localized heating and cooling. By monolithic integration of the Peltier element and with a silicon neural probe, the innovative system allows ...
Zoia Naumkina, Kanghwan Kim, Wesley Charles Smith, Keuntae Kim, Shinwoo Lee, Jiwan Woo, Il‐Joo Cho   +6 more
wiley   +1 more source

Visualization of Swirling Flow in a 3-dimensional Helical Stent Model using Color-coded Circulation and 4-dimensional Flow Magnetic Resonance Imaging. [PDF]

Interv Radiol (Higashimatsuyama)
Maruyama M, Kawasumi T, Kimura Y, Aso H, Kaneko K, Sasaki S, Ohta M.   +6 more
europepmc   +1 more source

Nanomedicine Meets Immunotherapy: Advancing Adoptive Cell Therapy with Nanoparticles in the Treatment of Cancer with Sustainability Perspectives

Advanced Science, EarlyView.
This review surveys nanoparticle‐based strategies to enhance adoptive cell therapy, particularly CAR‐T cell approaches, in solid tumor treatment. It describes how nanoparticles can improve tumor immunogenicity and T‐cell infiltration while reducing toxicity, and how they enable in vivo CAR‐T cell generation.
Erica Frostegård, Tatiana Bobrova, Amalie Leinebø, Thibault Leray, Shayamita Ghosh, Lorena García‐Hevia, Chiara Puccinelli, Lorenzo Riccio, Jacopo Sorani, Davide Bonifazi, Julien Caumartin, Emmanuel Donnadieu, Florence Gazeau, Roland Hischier, Else Marit Inderberg, Mónica L. Fanarraga, Maria Loustau, Bernd Nowack, Sébastien Wälchli, Cécilia Ménard‐Moyon   +19 more
wiley   +1 more source

LBE Natural Circulation Fluid Dynamics Validation Project

, 2015
Regan Voit, Robert Prince, Dan G. Cacuci
openaire   +2 more sources