Results 211 to 220 of about 641,617 (352)

The effect of resolution on viscous dissipation measured with 4D flow MRI in patients with Fontan circulation: Evaluation using computational fluid dynamics [PDF]

, 2015
Merih Cibiş, Kelly Jarvis, Michael Markl, Michael J. Rose, Cynthia K. Rigsby, Alex J. Barker, Jolanda J. Wentzel   +6 more
openalex   +1 more source

Insights into the Dynamics and Binding Mechanisms of the Alkhumra Virus NS2B/NS3 Protease: A Molecular Dynamics Study

Advanced Theory and Simulations, EarlyView.
The ΔRMSF$\Delta {\rm RMSF}$ analysis reveals significant flexibility differences between free NS3 and the NS2B/NS3 complex, with notable deviations in specific regions. Key residues driving NS2B binding are identified, and the protonation state of catalytic serine affects oxyanion hole formation.
Jurica Novak, Shivananda Kandagalla, Ramesh Sistla   +2 more
wiley   +1 more source

Covert cerebrospinal fluid dynamics dysfunction: evolution from conventional to innovative therapies. [PDF]

Front Neurol
Xu Y, Yin H, Li L, Wang X, Hou Q.
europepmc   +1 more source

Sustained Vaccine Exposure Elicits More Rapid, Consistent, and Broad Humoral Immune Responses to Multivalent Influenza Vaccines

Advanced Science, EarlyView.
This work presents an injectable polymer‐nanoparticle hydrogel depot platform for delivering multivalent influenza vaccines which induces stronger and more durable immune responses. The technology provides broader protection, including against heterologous and potential pandemic strains (H5N1, H7N9, H9N2), and enhances the effectiveness of commercial ...
Olivia M. Saouaf, Ben S. Ou, Ye Eun Song, Joshua J. Carter, Jerry Yan, Carolyn K. Jons, Christopher O. Barnes, Eric A. Appel   +7 more
wiley   +1 more source

New Perspective on Aqueous Humor Circulation: Retina Takes the Lead. [PDF]

Int J Mol Sci
Ueki S, Suzuki Y.
europepmc   +1 more source

Cardiovascular fluid dynamics: a journey through our circulation [PDF]

Karthik Menon, Zinan Hu, Alison L. Marsden   +2 more
openalex   +1 more source

A Silk Fibroin Nanoparticle Hydrogel Loaded With NK1R Antagonist Has Synergistic Anti‐Inflammatory and Reparative Effects on Dry Eye Disease

Advanced Science, EarlyView.
This study develops a silk fibroin (SF) nanoparticles hydrogel targeting neurokinin 1 receptor with CP‐99994 (CP). Combining CP and SF to form stable nanoparticles while incorporating a flexible hydrogel material results in a sustained‐release ophthalmic drop formulation (SF@CP@Gel), which provides a long‐lasting ophthalmic formulation with anti ...
Bo Gong, Yi Liu, Huan Li, Xueming Ju, Dongfeng Li, Yuhao Zou, Xiaoxin Guo, Kai Dong, Jialing Xiao, Weijia Wu, Renjie Chai, Ruifan Zhang, Man Yu   +12 more
wiley   +1 more source

Editorial: CSF clearance in Alzheimer's disease and related dementias: exploring mechanisms and implications. [PDF]

Front Aging Neurosci
Li Y.
europepmc   +1 more source

Functional Polarization of Liver Macrophages by Glyco Gold Nanoparticles

Advanced Science, EarlyView.
Macrophages play a critical role in several pathophysiological diseases by being involved in the activation of adaptive and innate immune responses. The repolarization of macrophages using gold nanoparticles functionalized with glycans for a more selective targeting toward a restorative phenotype leads to an amelioration of the events.
Jennifer Fernandez Alarcon, Patricia Perez Schmidt, Nicolo Panini, Francesca Caruso, Martina B. Violatto, Naths Grazia Sukubo, Alberto Martinez‐Serra, Charlotte Blanche Ekalle‐Soppo, Annalisa Morelli, Giulia Yuri Moscatiello, Chiara Grasselli, Alessandro Corbelli, Fabio Fiordaliso, Joe Kelk, Laura Petrosilli, Giuseppe d'Orazio, Ruth Mateu Ferrando, Ariadna Verdaguer Ferrer, Cristina Fornaguera, Luigi Lay, Stefano Fumagalli, Sandro Recchia, Marco P. Monopoli, Laura Polito, Paolo Bigini, Giovanni Sitia   +25 more
wiley   +1 more source

Clinical implications of haemodynamics in symptomatic intracranial atherosclerotic stenosis by computational fluid dynamics modelling: a systematic review. [PDF]

Stroke Vasc Neurol
Liu Y, Li S, Liu H, Tian X, Liu Y, Li Z, Leung TW, Leng X.   +7 more
europepmc   +1 more source