Results 81 to 90 of about 245,968 (334)

The critical role of DNA damage‐inducible transcript 4 (DDIT4) in stemness character of leukemia cells and leukemia initiation

open access: yesMolecular Oncology, EarlyView.
Stemness properties, including quiescence, self‐renewal, and chemoresistance, are closely associated with leukemia relapse. Here, we demonstrate that DNA damage‐inducible transcript 4 (DDIT4) is induced in the hypoxic bone marrow niche and is essential for maintaining the stemness of AML1‐ETO9a leukemia cells.
Yishuang Li   +12 more
wiley   +1 more source

Numerical Simulation of the Two-phase Flow Inside Bubble Columns in the Fully Developed Flow

open access: yesChemical Engineering Transactions, 2023
This study refers to the simulation and analysis of fluid dynamics in a bubble column in fully developed flow through two numerical approaches, the variational method, and the finite volume method.
Pamela Palhares, Reginaldo Guirardello
doaj   +1 more source

Fluid dynamic regimes in circulating fluidized bed boilers—A mini-review

open access: yesChemical Engineering Science, 2022
Abstract The fluid dynamics in the furnaces of large-scale circulating fluidized bed (CFB) boilers are surprisingly little known in contrast to the many laboratory studies made on conditions related to chemical reactors. Two areas are surveyed in the present work: the bottom bed and the upper dilute zone of a furnace.
openaire   +2 more sources

Numerical experiments on vortex ring formation [PDF]

open access: yes, 2001
Numerical simulations are used to study the formation of vortex rings that are generated by applying a non-conservative force of long duration, simulating experimental vortex ring generation with large stroke ratio. For sufficiently long-duration forces,
Colonius, Tim   +2 more
core   +2 more sources

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

open access: yesMolecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan   +9 more
wiley   +1 more source

Dynamic Simulations on Enhanced Heat Recovery Using Heat Exchange PCM Fluid for Solar Collector

open access: yesEnergies, 2023
Facing the goal of carbon neutrality, energy supply chains should be more low-carbon and flexible. A solar chemical heat pump (SCHP) is a potential system for achieving this goal. Our previous studies developed a silicone-oil-based phase-change material (
Yawen Ren, Hironao Ogura
doaj   +1 more source

The tumor–microbe connection

open access: yesMolecular Oncology, EarlyView.
Tumor‐associated bacteria (TAB) dynamically influence cancer biology by modulating tumor progression, metastatic spread, and therapeutic efficacy. Their presence redefines the tumor microenvironment (TME) as a microbial–host interface, yet mechanistic insights remain limited. Understanding TAB colonization routes, functional impacts, and crosstalk with
Gerlanda Vella, Maria Rescigno
wiley   +1 more source

Influence of hydrodynamic and functional nonlinearities of blood flow in the cerebral vasculature on cerebral perfusion and autoregulation pressure reserve

open access: yesScientific Reports, 2023
Ensuring the transport of oxygenated blood to the brain is one of the priorities of the human body. In the literature, there are many models of cerebral circulation with different levels of complexity used to assess pathological conditions, support ...
Adam Piechna, Krzysztof Cieślicki
doaj   +1 more source

Starting flow through nozzles with temporally variable exit diameter [PDF]

open access: yes, 2005
Starting flow through a nozzle or orifice typically results in the transient formation of a leading vortex ring and trailing jet. Experiments are conducted to investigate the dynamics of this process in the case of a temporally variable nozzle exit ...
Dabiri, John O., Gharib, Morteza
core  

Current trends in single‐cell RNA sequencing applications in diabetes mellitus

open access: yesFEBS Open Bio, EarlyView.
Single‐cell RNA sequencing is a powerful approach to decipher the cellular and molecular landscape at a single‐cell resolution. The rapid development of this technology has led to a wide range of applications, including the detection of cellular and molecular mechanisms and the identification and introduction of novel potential diagnostic and ...
Seyed Sajjad Zadian   +6 more
wiley   +1 more source

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