Results 61 to 70 of about 45,939 (308)
CX3CL1 in Early Detection of Alzheimer's Disease: Plasma Dynamics Across Age and Disease Stages
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Backgrounds Alzheimer's disease (AD) is characterized by amyloid‐beta plaques, tau tangles, and neuroinflammation. C‐X3‐C motif chemokine ligand 1 (CX3CL1, also known as fractalkine), a neuroimmune chemokine implicated in AD pathogenesis, shows inconsistent alterations in plasma/serum across studies.
Ling Wang +6 more
wiley +1 more source
Optimization of Meridional Flow Channel Design of Pump Impeller
International Journal of Rotating Machinery, 2004 The meridional flow channel design of a pump impeller affects its performance. However, since so many design parameters exist, a new design method is proposed in which a meridional and blade-to-blade flow channel is designed by the parallel use of the ...
Sunao Miyauchi +3 more
doaj +1 more source
Functional and Structural Evidence of Neurofluid Circuit Aberrations in Huntington Disease
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Disrupted neurofluid regulation may contribute to neurodegeneration in Huntington disease (HD). Because neurofluid pathways influence waste clearance, inflammation, and the distribution of central nervous system (CNS)–delivered therapeutics, understanding their dysfunction is increasingly important as targeted treatments emerge.
Kilian Hett +8 more
wiley +1 more source
ASAIO Journal, 2020 Extracorporeal membrane oxygenation (ECMO) is increasingly deployed to provide percutaneous mechanical circulatory support despite incomplete understanding of its complex interactions with the failing heart and its effects on hemodynamics and perfusion.
Farhad Rikhtegar Nezami +3 more
openaire +3 more sources
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Facioscapulohumeral muscular dystrophy (FSHD) is one of the most debilitating and common muscular dystrophies. Despite its severity, no approved therapy exists for FSHD patients. However, several therapeutic candidates are currently under development, and some have recently entered clinical trials, marking the need for reliable ...
Mustafa Bilal Bayazit +11 more
wiley +1 more source
Effect of Prandtl's ration on balance in geophysical turbulence
, 2015 Support for this research has come from the UK Engineering and Physical Sciences Research Council (grant no. EP/H001794/1).The fluid dynamics of the atmosphere and oceans are to a large extent controlled by the slow evolution of a scalar field called ...
McKiver, William Joseph +1 more
core +1 more source
Planktonic communities and chaotic advection in dynamical models of Langmuir circulation [PDF]
, 1998 A deterministic mechanism for the production of plankton patches within a typical medium scale oceanic structure is proposed and investigated. By direct numerical simulation of a simple model of Langmuir circulation we quantify the effects of unsteady ...
Bees, M.A.
core +1 more source
β‐Catenin/c‐Myc Axis Modulates Autophagy Response to Different Ammonia Concentrations
Advanced Biology, Volume 9, Issue 3, March 2025.Ammonia, detoxified by the liver into urea and glutamine, impacts autophagy differently at varying levels. Low ammonia activates autophagy via c‐Myc and β‐catenin, while high levels suppress it. Using Huh7 cells and Spf‐ash mice, c‐Myc's role in cytoprotective autophagy is revealed, offering insights into hyperammonemia and potential therapeutic ...
S. Sergio +11 more
wiley +1 more source
1989 summer study program in Geophysical Fluid Dynamics : general circulation of the oceans [PDF]
, 1989 The success of this summer's Geophysical Fluid Dynamics Program owes much to Myrl Hendershott's excellent and engaging survey of the Oceans General Circulation, including recent developments In the Theory of Recirculation Gyres and Thermocline ...
Steering Committee +1 more
core +1 more source
Advanced Engineering Materials, EarlyView.The tribological behavior of 100Cr6 steel spheres textured via Vickers microindentation is evaluated under lubricated sliding by varying both dimple size and density. Fine and dense textures significantly reduce friction across all lubrication regimes, while large dimples increase it.
Farideh Davoodi +3 more
wiley +1 more source