Results 81 to 90 of about 45,939 (308)

Modelling single ventricle physiology: Review of engineering tools to study first stage palliation of hypoplastic left heart syndrome

Frontiers in Pediatrics, 2013
First stage palliation of hypoplastic left heart syndrome (HLHS), i.e. the Norwood operation, results in a complex physiological arrangement, involving different shunting options (modified Blalock-Taussig, RV-PA conduit, central shunt from the ascending ...
Giovanni eBiglino, Giovanni eBiglino, Alessandro eGiardini, Tain-Yen eHsia, Richard eFigliola, Andrew M Taylor, Andrew M Taylor, Silvia eSchievano, Silvia eSchievano   +8 more
doaj   +1 more source

The CLIVAR C20C project: which components of the Asian-Australian monsoon circulation variations are forced and reproducible? [PDF]

, 2009
A multi-model set of atmospheric simulations forced by historical sea surface temperature (SST) or SSTs plus Greenhouse gases and aerosol forcing agents for the period of 1950-1999 is studied to identify and understand which components of the Asian ...
Lau, N.C., Wen, Xinyu, Spryshev, P., Voldoire, A., Kinter, J., Schubert, S., Cherchi, A., Kucharski, F., Scaife, A., Li, Lijuan, Zhou, T., Yoon, J. H., Wu, B., Wu, Bo, Lau, N. C., Kusunoki, S., Knight, J. R., Bronnimann, S., Zeng, N., Fereday, D., Fischer, A. M., Pegion, P., Folland, C. K., Wen, X., Broennimann, S., Jin, K. E., Scaife, A. A., Sporyshev, P., Nath, M. J., Voldoire, A.., Zhou, Tianjun, Nakaegawa, T., Rozanov, E., Feredey, D., Navarra, A., Li, L.   +35 more
core   +1 more source

Blood Biomarkers and Surface‐Enhanced Raman Spectroscopy for Gout: A Comprehensive Review

Advanced Functional Materials, EarlyView.
Schematic illustrating gout disease progression from asymptomatic hyperuricemia to chronic tophaceous disease, highlighting the limitations of conventional imaging and biochemical diagnostics and the potential of engineered SERS platforms for ultrasensitive blood‐based detection of urate‐related biomarkers across disease stages, with the color gradient
Isuri Perera, Chiranjeevi Kanike, Appurva Tiwari, Hongyan Wu, Larry D. Unsworth, Ben Bin Xu, Xuehua Zhang   +6 more
wiley   +1 more source

A Review of the Dynamics and Oscillations of the Atmosphere

, 2012
The atmosphere is a complex, dynamic system and the weather depends on its state. There are many different phenomena that affect the state of the atmosphere - some only involve the atmosphere, others involve the interaction between the atmosphere and the
Ross, Joseph
core  

Computational fluid dynamics in cardiovascular disease [PDF]

, 2011
Computational fluid dynamics (CFD) is a mechanical engineering field for analyzing fluid flow, heat transfer, and associated phenomena, using computer-based simulation.
이병권
core   +1 more source

Functional Precision Oncology Approach Using Nanoliter Droplet Array for Drug Sensitivity Testing in Lung Cancer

Advanced Healthcare Materials, EarlyView.
A miniaturized drug sensitivity and resistance testing (DSRT) workflow based on the Droplet Microarray (DMA) platform enables functional drug testing using minimal patient‐derived tumor material. By screening nanoliter‐scale droplets containing as few as 300 cells, this approach generates reproducible and tumor‐specific drug response profiles ...
Maryam Salarian, Vicky L. Schiling, Thomas Muley, Michael Allgäuer, Florian Eichhorn, Michael Meister, Marc A. Schneider, Anna A. Popova   +7 more
wiley   +1 more source

Fluid Dynamics Inside the Brain Barrier: Current Concept of Interstitial Flow, Glymphatic Flow, and Cerebrospinal Fluid Circulation in the Brain

, 2018
The discovery of the water specific channel, aquaporin, and abundant expression of its isoform, aquaporin-4 (AQP-4), on astrocyte endfeet brought about significant advancements in the understanding of brain fluid dynamics.
Ingrid L. Kwee, Tsutomu Nakada
core   +1 more source

Multidimensional Cellular Micro‐Compartments to Model Invasive Lobular Carcinoma Dormancy

Advanced Healthcare Materials, EarlyView.
Invasive lobular carcinoma (ILC) is an understudied subtype of breast cancer that is susceptible to late recurrences. In this study, micro‐compartmentalization techniques spanning multiple dimensions, including 2D, pseudo‐3D, and 3D, are integrated to uncover the mechanisms underlying ILC dormancy, revealing the central role of p27Kip1.
Xilal Y. Rima, Sarmila Majumder, Divya S. Patel, Chunyu Hu, Hong Li, Xin Huang, Kim Truc Nguyen, Jacob Doon‐Ralls, Chiranth K. Nagaraj, Mangesh D. Hade, Setty M. Magaña, Eswar Shankar, Xiaoli Zhang, Daniel G. Stover, Bhuvaneswari Ramaswamy, Eduardo Reátegui   +15 more
wiley   +1 more source

ExoCubed: A Riemann-solver-based Cubed-sphere Dynamic Core for Planetary Atmospheres

The Astrophysical Journal
The computational fluid dynamics on a sphere is relevant to global simulations of geophysical fluid dynamics. Using the conventional spherical–polar (or lat–lon) grid results in a singularity at the poles, with orders-of-magnitude-smaller cell sizes at ...
Sihe Chen, Cheng Li
doaj   +1 more source

One‐Step Microfluidic Manufactured Fucose‐Decorated Sweetosomes Choose the Time and the Road for Their Intracellular Journey to Cancer Treatment

Advanced Healthcare Materials, EarlyView.
Sweetosomes, a new class of fucose‐decorated liposomes, are developed via a one‐step microfluidic process without surface chemistry. This study elucidates their main caveolae‐mediated entry and distinct endosomal trafficking. These nanostructures demonstrate superior endosomal escape, organelle acidity modulation, and prolonged plasma persistence ...
Mattia Tiboni, Mariele Montanari, Shiva Khorshid, Michele Verboni, Andrea Duranti, Simone Lucarini, Daniele Lopez, Annalisa Aluigi, Gianluca Morganti, Michele Menotta, Giovanna Panza, Daniel J. Klionsky, Barbara Canonico, Luca Casettari   +13 more
wiley   +1 more source