Results 11 to 20 of about 179 (145)
Diagnosis and management of the overlap syndromes of autoimmune hepatitis. [PDF]
BACKGROUND: Autoimmune hepatitis may have cholestatic features that are outside the classical phenotype and that resemble findings in other immune‐mediated liver diseases. These cholestatic phenotypes have been designated ‘overlap syndromes’. OBJECTIVES: To recognize the overlap syndromes in adults and manage them appropriately.
Czaja AJ.
europepmc +2 more sources
Clinical significance of autoantibodies to p53 protein in patients with autoimmune liver diseases. [PDF]
Mutations in the p53 gene leading to conformational changes in the p53 protein have been well established in many human cancers. Conformational changes and/or cellular accumulation of the protein may induce an immune response, resulting in circulating autoantibodies to p53, which have been documented in several types of cancers.
Himoto T +9 more
europepmc +2 more sources
BACKGROUND: Large‐scale epidemiological studies of primary biliary cirrhosis (PBC) have been hindered by difficulties in case ascertainment. OBJECTIVE: To develop coding algorithms for identifying PBC patients using administrative data – a widely available data source.
Robert P Myers +7 more
wiley +1 more source
A common characteristic of all chronic liver diseases is the occurrence and progression of fibrosis toward cirrhosis. Consequently, liver fibrosis assessment plays an important role in hepatology. Besides its importance for prognosis, determining the level of fibrosis reveals the natural history of the disease and the risk factors associated with its ...
Ludovico Abenavoli +2 more
wiley +1 more source
Primary sclerosing cholangitis (PSC) is a condition of unknown etiology that causes progressive inflammation, fibrosis and obliteration of the intrahepatic and extrahepatic biliary tree. There is no medical cure, and ursodeoxycholic acid and other drugs have not been shown to affect the natural history of the disease.
Young-Mee Lee
wiley +1 more source
Primary Biliary Cirrhosis and Hemolytic Anemia Confusing Serum Bilirubin Levels
Hemolysis is observed in more than 50% of patients with cirrhosis. However, there has been little documention of the association of primary biliary cirrhosis with autoimmune hemolytic anemia. Two cases, found within a single practice, of primary biliary cirrhosis coexisting with autoimmune hemolysis and a third case coexisting with hereditary ...
M Brackstone, Cameron N Ghent
wiley +1 more source
Acute graft‐versus‐host disease (GVHD) is a common complication after bone marrow transplantation, with characteristic rash and diarrhea being the most common features. After liver transplantation, however, this phenomenon is very rare. Most transplant patients are on a variety of medications, including immunosuppressants; therefore, the differential ...
Joseph Romagnuolo +3 more
wiley +1 more source
Prevalence of IgA Antibodies to Endomysium and Tissue Transglutaminase in Primary Biliary Cirrhosis
The association between celiac disease and primary biliary cirrhosis has been described in several case reports and small screening studies, with varying prevalence rates. Stored sera from 378 patients with primary biliary cirrhosis were tested for immunoglobulin (Ig) A endomysium and tissue transglutaminase antibodies.
Helen R Gillett +3 more
wiley +1 more source
Coexistence cirrhose biliaire primitive et sclérodermie systémique : étude avec capillaroscopie et immunologie [PDF]
Objectif : Déterminer la prévalence de la Sclérose systémique (SSc) chez les patients atteints de cirrhose biliaire primitive (CBP) et décrire les caractéristiques cliniques, pronostiques, immunologiques et capillaroscopiques chez les patients avec et ...
Kerbachi, Meriem
core +3 more sources
Modulation expérimentale de la mort cellulaire [PDF]
L'apoptose joue un rôle essentiel dans la physiopathologie hépatique. La voie de Fas a notamment été impliquée dans certaines maladies autoimmunes comme la cirrhose biliaire primitive, les hépatites qu'elles soient d'origine autoimmune ou virale ou enfin
Claudia Mitchell +6 more
core +1 more source

