Results 121 to 130 of about 691,603 (403)

Different behaviour of the N-terminal and C-terminal fragment of proatrial natriuretic factor in plasma of healthy subjects as well as of patients with cirrhosis [PDF]

, 1990
N-terminal (atrial natriuretic factor (ANF) 1-98) and C-terminal (ANF 99-126) fragments of proatrial natriuretic factor (NTA and CTA, respectively) were determined in plasma of healthy subjects adopting different postures and in patients with cirrhosis ...
Arendt, Rainer M., Cantin, M., Gerbes, Alexander L., Paumgartner, Gustav, Thibault, G., Vollmar, Angelika M.   +5 more
core   +1 more source

Sarcopenia in cirrhosis: from pathogenesis to interventions

Journal of gastroenterology, 2019
Sarcopenia (severe muscle depletion) is a prevalent muscle abnormality in patients with cirrhosis that confers poor prognosis both pre- and post-liver transplantation. The pathogenesis of sarcopenia is multifactorial and results from an imbalance between
M. Ebadi, R. Bhanji, V. Mazurak, A. Montaño-Loza   +3 more
semanticscholar   +1 more source

Spatial Transcriptomics and snRNA‐seq Expose CAF Niches Orchestrating Dual Stromal‐Immune Barriers in Hepatocellular Carcinoma

Advanced Science, EarlyView.
HmmyCAFs may form a triple immunosuppressive niche: possibly secrete ECM (POSTN, etc.) as physical barriers to block CD8⁺ T cells, induce CD8⁺ T exhaustion via those molecules, and use HIF‐1α‐driven metabolism to create acidic, nutrient‐poor microenvironments that suppress T cells.
Yingxue Li, Changxiang Huan, Haoting Sun, Wei Zhang, Zhen Guo, Chuanyu Li, Jia Yao, Zhiqi Zhang, Shizhe Yu, Qiongzhu Dong, Lunxiu Qin, Jinze Li, Lianqun Zhou   +12 more
wiley   +1 more source

Predictive model of in-hospital mortality in liver cirrhosis patients with hyponatremia: an artificial neural network approach

Scientific Reports
Hyponatremia can worsen the outcomes of patients with liver cirrhosis. However, it remains unclear about how to predict the risk of death in cirrhotic patients with hyponatremia. Patients with liver cirrhosis and hyponatremia were screened.
Zhaohui Bai, Yuhang Yin, Wentao Xu, Gang Cheng, Xingshun Qi   +4 more
doaj   +1 more source

Alcohol Consumption and Risk of Liver Cirrhosis: A Systematic Review and Meta-Analysis.

American Journal of Gastroenterology, 2019
OBJECTIVES To systematically summarize the risk relationship between different levels of alcohol consumption and incidence of liver cirrhosis. METHODS MEDLINE and Embase were searched up to March 6, 2019, to identify case-control and cohort studies ...
M. Roerecke, A. Vafaei, O. Hasan, Bethany R Chrystoja, Marcus Cruz, Roy Lee, M. Neuman, J. Rehm   +7 more
semanticscholar   +1 more source

Gut microbiota–derived short‐chain fatty acids regulate group 3 innate lymphoid cells in HCC

Hepatology, EarlyView., 2022
Abstract Background and Aims Type 3 innate lymphoid cells (ILC3s) are essential for host defense against infection and tissue homeostasis. However, their role in the development of HCC has not been adequately confirmed. In this study, we investigated the immunomodulatory role of short‐chain fatty acids (SCFAs) derived from intestinal microbiota in ILC3
Chupeng Hu, Bingqing Xu, Xiaodong Wang, Wen‐Hua Wan, Jinying Lu, Deyuan Kong, Yu Jin, Wenhua You, Hua Sun, Xiaoxin Mu, Dongju Feng, Yun Chen   +11 more
wiley   +1 more source

Therapeutic effects of serum extracellular vesicles in liver fibrosis

Journal of Extracellular Vesicles, 2018
The lack of approved therapies for hepatic fibrosis seriously limits medical management of patients with chronic liver disease. Since extracellular vesicles (EVs) function as conduits for intercellular molecular transfer, we investigated if EVs from ...
Li Chen, Ruju Chen, Sherri Kemper, Min Cong, Hong You, David R. Brigstock   +5 more
doaj   +1 more source

Natural history of patients with non cirrhotic portal hypertension: Comparison with patients with compensated cirrhosis [PDF]

, 2018
Background. The knowledge of natural history of patients with portal hypertension (PH) not due to cirrhosis is less well known than that of cirrhotic patients. Aim.
Aprile, Francesca, Gioia, Stefania, Merli, Manuela, Nardelli, Silvia, Nicoletti, Valeria, Pasquale, Chiara, Pentassuglio, Ilaria, Riggio, Oliviero   +7 more
core   +1 more source

Liver Cancer: Connections with Obesity, Fatty Liver, and Cirrhosis.

Annual Review of Medicine, 2016
The burden of hepatocellular carcinoma (HCC), the most common form of liver cancer, is steadily growing because obesity, type 2 diabetes, and nonalcoholic fatty liver disease (NAFLD) are replacing viral- and alcohol-related liver disease as major ...
A. Marengo, C. Rosso, E. Bugianesi
semanticscholar   +1 more source

Association Between Distance to the Transplant Center and Survival Following Living Donor Liver Transplantation

Annals of Gastroenterological Surgery, EarlyView.
This study investigated the impacts of distance to transplant center on posttransplant survival following LDLT. Patients living further away from the transplant center had worse graft and patient survival rates than those of patients living closer, probably due to less frequency of follow‐up visits, and living > 40 miles from our treatment center was ...
Hajime Matsushima, Akihiko Soyama, Takanobu Hara, Ayaka Kinoshita, Takashi Hamada, Kazushige Migita, Ayaka Satoh, Hajime Imamura, Tomohiko Adachi, Susumu Eguchi   +9 more
wiley   +1 more source