Journal of Applied Toxicology, EarlyView.ABSTRACT Monocrotaline (MCT), a plant‐derived pyrrolizidine alkaloid, is well known for its hepatotoxic effects. However, full elucidation of the mechanisms underlying MCT‐induced hepatotoxicity, as well as the development of reliable biomarkers for early detection and monitoring, requires an integrated evaluation of biochemical, molecular, and ...
Ali Şenol +4 more
wiley +1 more source
Cirrhosis-associated intracranial shunting lesions: illustrative case. [PDF]
J Neurosurg Case LessonsHaver J +5 more
europepmc +1 more source
Serum Midkine as a Biomarker for Hepatocellular Carcinoma Treatment Response and Prognostication
Journal of Clinical Laboratory Analysis, EarlyView.Up‐to‐date, tumor markers are considered more helpful in the evaluation of treatment response and prognostication rather than diagnosis. Identifying a valid biomarker to help clinical management of hepatocellular carcinoma (HCC) is still a challenge, especially the alpha‐fetoprotein (AFP) negative HCC. This study evaluated the efficacy of serum Midkine
Yanfang Luo +3 more
wiley +1 more source
Four-dimensional flow MRI for identifying high-risk esophageal varices: a comparison and combination with spleen volume and splenic extracellular volume fraction. [PDF]
Insights ImagingLi X +9 more
europepmc +1 more source
Soluble B7‐H6 as a Novel Diagnostic Biomarker for Post‐Hepatitis B Cirrhosis: A Clinical Value Study
Journal of Clinical Laboratory Analysis, EarlyView.This study investigates the potential of soluble B7‐H6 (sB7‐H6) as a novel diagnostic biomarker for post‐hepatitis B cirrhosis. The infographic visually presents the following key points: (1) Liver Disease Progression: Chronic hepatitis B (CHB) progresses to liver cirrhosis (LC), with serum sB7‐H6 levels increasing stepwise as the disease advances. (2)
Kaiyong Chen +4 more
wiley +1 more source
Imperfect Maturation of Erythroid Progenitors in Patients with Cirrhosis-Associated Anemia. [PDF]
Curr Issues Mol BiolLal D +4 more
europepmc +1 more source
Journal of Clinical Ultrasound, EarlyView.Shear wave elastography demonstrated moderate diagnostic accuracy for detecting congestive liver disease in patients with structural heart disease. Increased liver stiffness was associated with echocardiographic markers of venous congestion, supporting the concept that elastography may serve as a noninvasive marker of cardiohepatic interaction ...
Edinéia Camargo Dziadzio +4 more
wiley +1 more source
Sodium-Glucose Cotransporter 2 Inhibitors Versus Dipeptidyl Peptidase-4 Inhibitors in Patients With Type 2 Diabetes Mellitus and Liver Cirrhosis: A Systematic Review and Meta-Analysis. [PDF]
CureusShetty USA +7 more
europepmc +1 more source
Journal of Hospital Medicine, EarlyView.Abstract Background Diagnostic error is a major patient safety concern in hospitals, yet most studies have focused on selected high‐risk subgroups, leaving the broader general internal medicine inpatient population understudied. Objectives To determine the incidence, contributing factors, resulting harm, and predictors of diagnostic error in medical ...
Caterina E. Marx +9 more
wiley +1 more source
Rethinking sustained recompensation in MASLD cirrhosis: The value of pharmacological maintenance. [PDF]
Hepatol CommunToshikuni N, Shimatani M.
europepmc +1 more source