Interleukin‐18 signaling promotes activation of hepatic stellate cells in mouse liver fibrosis
Hepatology, EarlyView., 2022 Interleukin‐18 signaling promotes activation of hepatic stellate cells in mouse liver fibrosis. Abstract Background and Aims Nucleotide‐binding oligomerization domain‐like receptor‐family pyrin domain‐containing 3 (NLRP3) inflammasome activation has been shown to result in liver fibrosis.
Jana Knorr +19 more
wiley +1 more source
TOTAL EXCHANGEABLE SODIUM, TOTAL EXCHANGEABLE POTASSIUM, AND TOTAL BODY WATER IN EDEMATOUS PATIENTS WITH CIRRHOSIS OF THE LIVER AND CONGESTIVE HEART FAILURE1 [PDF]
, 1958 L. W. Birkenfeld +3 more
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ESC Heart Failure, EarlyView.Abstract Aims There are limited tools to predict long‐term mortality among patients hospitalized with acute heart failure (AHF) in China. This study aimed to develop and validate a model to predict long‐term mortality risk among patients who were hospitalized with AHF and discharged alive.
Wei Wang +8 more
wiley +1 more source
AASLD practice guidance on drug, herbal, and dietary supplement–induced liver injury
, 2022 Hepatology, EarlyView.
Robert J. Fontana +6 more
wiley +1 more source
Hepatology, EarlyView., 2022 NRPT 1X reduces ALT and ceramide 14:0 in 65% of subjects as compared to only 28% in the placebo group. Abstract Background and Aims The prevalence of NAFLD is increasing globally and on a path to becoming the most frequent cause of chronic liver disease. Strategies for the prevention and treatment of NAFLD are urgently needed.
Ryan W. Dellinger +7 more
wiley +1 more source
Towards Synergistic Deep Learning Models for Volumetric Cirrhotic Liver Segmentation in MRIs [PDF]
arXivLiver cirrhosis, a leading cause of global mortality, requires precise segmentation of ROIs for effective disease monitoring and treatment planning. Existing segmentation models often fail to capture complex feature interactions and generalize across diverse datasets.
arxiv
THE EFFECT OF CHANGING SERUM OSMOLALITY ON THE RELEASE OF ANTIDIURETIC HORMONE IN CERTAIN PATIENTS WITH DECOMPENSATED CIRRHOSIS OF THE LIVER AND LOW SERUM OSMOLALITY [PDF]
, 1959 Laurence E. Earley, Charles A. Sanders
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Secondary sclerosing cholangitis in patients suffering cardiogenic shock
ESC Heart Failure, EarlyView.Abstract Aims Cardiogenic shock (CS) patients suffer from severe organ hypoperfusion, yet the incidence of secondary sclerosing cholangitis in critically ill patients (SSC‐CIP) in CS is poorly described. Given the limited evidence and severity of this syndrome, we aimed to further investigate SSC‐CIP in the context of CS.
Hugo Lanz +25 more
wiley +1 more source
c‐Rel–dependent Chk2 signaling regulates the DNA damage response limiting hepatocarcinogenesis
Hepatology, EarlyView., 2022 In response to genotoxic injury, c‐Rel upregulates ATM‐Chk2‐p53 pathway DNA damage proteins to limiting hepatocarcinogenesis. Abstract Background and Aims Hepatocellular carcinoma (HCC) is a leading cause of cancer‐related death. The NF‐κB transcription factor family subunit c‐Rel is typically protumorigenic; however, it has recently been reported as a
Jack Leslie +17 more
wiley +1 more source