Predictors of 30-Day Readmission in Patients With Cirrhosis: A Retrospective Cohort Study. [PDF]
CureusAlbusta N, Yusuf A, Alrahma H.
europepmc +1 more source
Two stable gut microbiome guilds predict liver tumor class and treatment responses
iMeta, EarlyView.Gut microbiome alterations are linked to hepatocellular carcinoma (HCC), yet taxon‐based biomarkers often lack reproducibility. Using shotgun metagenomics from 120 resectable HCC (MT) and 76 benign hepatic tumor controls (BT), we reconstructed a stable interaction‐based Two Competing Guilds model (HCC‐TCG) comprising 142 genomes organized into two ...
Yang Liu +17 more
wiley +1 more source
Sarcopenia Risk Identified by Strength, Assistance With Walking, Rising From a Chair, Climbing Stairs, and Falls (SARC-F) in Patients With Cirrhosis: A Real-World Cross-Sectional Study. [PDF]
CureusAlbusta N, Yusuf A, Ali A.
europepmc +1 more source
N6‐Methyladenosine (m6A) in Liver Disease: Pathogenic Mechanisms and Therapeutic Potential
iNew Medicine, EarlyView.ABSTRACT Accumulating evidence highlights the critical role of epigenetic modifications, particularly N6‐methyladenosine (m6A), in liver disease. As the most abundant RNA modification in eukaryotic cells, m6A is dynamically regulated by multicomponent m6A methyltransferases (e.g., METTL3 and METTL14), demethylases (FTO and ALKBH5), and m6A‐binding ...
Yingfen Chen +6 more
wiley +1 more source
Multiscale Interactome-Guided Prioritization of Candidate Herbs and Active Compounds for Hepatic Cirrhosis Using a Biased Random Walk Algorithm. [PDF]
Curr Issues Mol BiolLee JH, Bak SB, Lee WY, Kim YK.
europepmc +1 more source
Zinc Finger E‐Box Binding Homeobox 1 Mediates Alcohol‐Induced Liver Disease
iNew Medicine, EarlyView.Alcohol intake leads to the upregulation of ZEB1, which activates the YAP‐IL‐1β/MCP‐1 pathway, resulting in the activation of liver inflammation and the induction of hepatocyte apoptosis. ABSTRACT Hepatitis resulting from alcoholic liver disease (ALD) is an important risk factor for liver cancer. It is essential to understand the role of ALD to prevent
Boyu Zhang +5 more
wiley +1 more source
Fecal microbiota transplantation in chronic liver disease: Current and future state of the art. [PDF]
Hepatol CommunBloom P, Khanna S.
europepmc +1 more source
The Role of Endothelin‐1 in Autoimmune Diseases: Mechanistic Insights and Therapeutic Targets
iNew Medicine, EarlyView.The Role of Endothelin‐1 in Autoimmune Diseases. NF‐κB: nuclear factor kappa‐B; MAPK: mitogen‐activated protein kinase; PI3K: phosphoinositide 3‐kinase; ROS: reactive oxygen species; CTGF: connective tissue growth factor; TGF‐β: transforming growth factor‐β.
Xun Gong +5 more
wiley +1 more source
Editorial: Treatment and prognostic assessment of liver cirrhosis and its complications, volume II
Frontiers in MedicineWei Zhang +5 more
doaj +1 more source