Results 341 to 350 of about 691,603 (403)

Evaluation of the Pharmacokinetics, Disposition, and Metabolism of Miricorilant, a Novel Glucocorticoid Receptor Modulator for the Treatment of Metabolic Dysfunction‐Associated Steatohepatitis in Nonclinical and Clinical Studies

open access: yesThe Journal of Clinical Pharmacology, EarlyView.
Abstract Miricorilant is a novel selective glucocorticoid receptor (GR) modulator with mixed agonist/antagonist effects at the GR and modest antagonism at the mineralocorticoid receptor that is being developed for the treatment of metabolic dysfunction‐associated steatohepatitis.
Hazel J. Hunt   +3 more
wiley   +1 more source

Plasma atrial natriuretic factor in patients with cirrhosis [PDF]

open access: yes, 1985
Arendt, Rainer M.   +5 more
core  

In Vitro and Clinical Evaluation of Potential Interactions of Bemnifosbuvir with Drug Transporters

open access: yesThe Journal of Clinical Pharmacology, EarlyView.
Abstract Bemnifosbuvir is a novel oral guanosine nucleotide prodrug candidate for the treatment of chronic hepatitis C virus infection. Potential drug–drug interactions (DDIs) of bemnifosbuvir as a substrate or perpetrator with regard to ATP‐binding cassette (ABC) and solute carrier (SLC) transporters were evaluated in vitro and in clinical studies ...
Xiao‐Jian Zhou   +9 more
wiley   +1 more source

Alcohol-related liver disease. [PDF]

open access: yesGastroenterol Rep (Oxf)
Herms Q, Gratacós-Ginès J, Pose E.
europepmc   +1 more source

Outcomes of Patients With Unresectable Cholangiocarcinoma After Portal Vein Embolization: A Propensity Score‐Matched Analysis

open access: yesJournal of Hepato-Biliary-Pancreatic Sciences, EarlyView.
ABSTRACT Background This study aimed to evaluate the outcomes of patients with unresectable cholangiocarcinoma (CCA) who underwent portal vein embolization (PVE) with a focus on overall survival (OS) and the frequency of biliary drainage (BD). Methods In this retrospective analysis, we evaluated 255 patients with unresectable CCA; 56 patients underwent
Ho Seung Lee   +8 more
wiley   +1 more source

Thermostable enzyme isoforms, continuously producing monocomponent superoxide radicals, from human postoperative serous fluids: isolation and properties. [PDF]

open access: yesBMC Cancer
Simonyan RM   +11 more
europepmc   +1 more source

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