Results 1 to 10 of about 1,162,420 (313)

The Evolution of Gene Expression in cis and trans

Trends in Genetics, 2018
There is abundant variation in gene expression between individuals, populations, and species. The evolution of gene regulation and expression within and between species is thought to frequently contribute to adaptation. Yet considerable evidence suggests
Sarah Signor
exaly   +2 more sources

Large-scale cis- and trans-eQTL analyses identify thousands of genetic loci and polygenic scores that regulate blood gene expression

Nature Genetics, 2021
Trait-associated genetic variants affect complex phenotypes primarily via regulatory mechanisms on the transcriptome. To investigate the genetics of gene expression, we performed cis- and trans-expression quantitative trait locus (eQTL) analyses using ...
U. Võsa, A. Claringbould, H. Westra, M. Bonder, Patrick Deelen, B. Zeng, H. Kirsten, A. Saha, Roman Kreuzhuber, S. Yazar, H. Brugge, R. Oelen, Dylan H. de Vries, M. V. D. van der Wijst, S. Kasela, N. Pervjakova, I. Alves, M. Favé, M. Agbessi, M. Christiansen, R. Jansen, I. Seppälä, L. Tong, A. Teumer, K. Schramm, G. Hemani, J. Verlouw, H. Yaghootkar, Reyhan Sönmez Flitman, A. Brown, V. Kukushkina, A. Kalnapenkis, S. Rüeger, E. Porcu, J. Kronberg, J. Kettunen, Bernett Lee, Futao Zhang, Ting Qi, J. A. Hernandez, W. Arindrarto, F. Beutner, Julia Dmitrieva, Mahmoud Elansary, Benjamin P. Fairfax, M. Georges, B. Heijmans, A. Hewitt, M. Kähönen, Yungil Kim, J. Knight, P. Kovacs, K. Krohn, Shuang Li, M. Loeffler, U. Marigorta, Hailang Mei, Y. Momozawa, M. Müller-Nurasyid, M. Nauck, M. Nivard, B. Penninx, J. Pritchard, O. Raitakari, O. Rotzschke, E. Slagboom, C. Stehouwer, M. Stumvoll, P. Sullivan, P. '. ’t Hoen, J. Thiery, A. Tönjes, J. van Dongen, M. van Iterson, J. Veldink, U. Völker, R. Warmerdam, C. Wijmenga, M. Swertz, A. Andiappan, G. Montgomery, S. Ripatti, M. Perola, Z. Kutalik, E. Dermitzakis, S. Bergmann, T. Frayling, J. V. van Meurs, H. Prokisch, H. Ahsan, B. Pierce, T. Lehtimäki, D. Boomsma, B. Psaty, Sina A. Gharib, P. Awadalla, L. Milani, W. Ouwehand, K. Downes, O. Stegle, A. Battle, P. Visscher, Jian Yang, M. Scholz, J. Powell, G. Gibson, T. Esko, L. Franke   +107 more
semanticscholar   +1 more source

Deciphering the multi-scale, quantitative cis-regulatory code

Molecules and Cells, 2023
Summary Uncovering the cis-regulatory code that governs when and how much each gene is transcribed in a given genome and cellular state remains a central goal of biology.
Seungsoo Kim, J. Wysocka
semanticscholar   +1 more source

Plasma proteome analyses in individuals of European and African ancestry identify cis-pQTLs and models for proteome-wide association studies

Nature Genetics, 2022
Improved understanding of genetic regulation of the proteome can facilitate identification of the causal mechanisms for complex traits. We analyzed data on 4,657 plasma proteins from 7,213 European American (EA) and 1,871 African American (AA ...
Jingning Zhang, Diptavo Dutta, A. Köttgen, A. Tin, P. Schlosser, Morgan E. Grams, Benjamin Harvey, Bing Yu, E. Boerwinkle, J. Coresh, N. Chatterjee   +10 more
semanticscholar   +1 more source

The use of three chip high definition camera with modular enhancement system with white light cystoscopy during transurethral resection of bladder tumours. Does it improve carcinoma in situ detection? [PDF]

Egyptian Journal of Medical Research, 2022
The goal of our study is to assess if the use of Storz professional image enhancement system (SPIES) improve carcinoma in situ (CIS) detection. We conducted a prospective study on 35 patients of both sexes who have fulfilled the inclusion criteria from ...
Ahmed Abdelbary, Ossama Mohamad, Ahmed Abd El Latif, Almotasem Bellah Adel, Akram Elmarakbi   +4 more
doaj   +1 more source

cis-Regulatory Elements in Plant Development, Adaptation, and Evolution

Annual Review of Plant Biology, 2022
cis-Regulatory elements encode the genomic blueprints that ensure the proper spatiotemporal patterning of gene expression necessary for appropriate development and responses to the environment.
Alexandre P. Marand, A. Eveland, K. Kaufmann, Nathan M. Springer   +3 more
semanticscholar   +1 more source

Cis-regulatory sequences in plants: Their importance, discovery, and future challenges

The Plant Cell, 2021
The identification and characterization of cis-regulatory DNA sequences and how they function to coordinate responses to developmental and environmental cues is of paramount importance to plant biology.
Robert J. Schmitz, E. Grotewold, M. Stam
semanticscholar   +1 more source

Offset stable piezoresistive high-temperature pressure sensors based on silicon [PDF]

Journal of Sensors and Sensor Systems, 2016
The exploitation of new application fields and the drive to size reduction even in highly stable pressure sensing systems makes the extension of the operating temperature range of the microelectromechanical sensors (MEMS) essential.
R. Täschner, E. Hiller, M. Blech
doaj   +1 more source

Human-Robot Interaction in Groups: Methodological and Research Practices

Multimodal Technologies and Interaction, 2021
Understanding the behavioral dynamics that underline human-robot interactions in groups remains one of the core challenges in social robotics research. However, despite a growing interest in this topic, there is still a lack of established and validated ...
Raquel Oliveira, Patrícia Arriaga, Ana Paiva   +2 more
doaj   +1 more source

Russian-тajik cooperation as a factor of stability in Central Asia (1992– 2022) [PDF]

Омский научный вестник: Серия "Общество. История. Современность", 2022
The article analyzes the historical experience of cooperation between the Russian Federation and the Republic of Tajikistan for 30 years. Special attention is paid to political, military, economic, trade and scientific cooperation.
T. K. Tursunov, S. V. Novikov
doaj   +1 more source