Results 281 to 290 of about 416,036 (340)

A CEBPB/TYMP/GDF15 signaling axis mediates tumor growth and cisplatin resistance in bladder cancer. [PDF]

Transl Oncol
Tian S, Wang C, Zhao X, Xuan Y, Wei W, Dong Y, Tao W, Zhang C, Cai T, Liu C, Huang Y, Zhang X.   +11 more
europepmc   +1 more source

Photocleavable Systems for Cell Biology: Conceptual Design across Molecular Modalities

ChemBioChem, EarlyView.
Light‐triggered bond cleavage is an essential biotechnology in chemical biology research. This concept highlights three photocleavable modalities—proteins, small molecules, and metal complexes—distilling design principles for wavelength tuning, cleavage efficiency, and biocompatibility.
Masahiko Yoshimura, Tomoko Inose
wiley   +1 more source

Comparative Antioxidant Protection of Cochlear Hair Cells from Ototoxins. [PDF]

Molecules
Ryan AF, Pak K, Lee EJ, Kurabi A.
europepmc   +1 more source

Targeting Cryptochromes in Chronic Diseases

Cell Biology International, EarlyView.
ABSTRACT The circadian clock generates 24‐h molecular rhythms through transcription–translation negative feedback loops (TTFLs) and regulates daily physiological processes such as sleep–wake cycles, body temperature, hormone secretion, metabolism, and immune function.
Takuro Toda, Tsuyoshi Hirota
wiley   +1 more source

Prediction of Cervical Cancer Progression Leveraging HPV16 Integration-Related Genes. [PDF]

Int J Womens Health
Yang Y, Sun C, Wang H.
europepmc   +1 more source

Vinpocetine Overcomes Paclitaxel Resistance in a Triple‐Negative Breast Cancer Cell Line

Cell Biology International, EarlyView.
ABSTRACT Paclitaxel is a first‐line treatment for triple‐negative breast cancer (TNBC), but its efficacy is commonly limited by tumor‐cell resistance. Vinpocetine is a well‐tolerated dietary supplement with pleiotropic cellular effects, including potential anti‐tumor activity.
Hsiao‐Hui Kuo, Chien‐Wei Huang, Wei‐Rou Chiang, Ling‐Huei Yih   +3 more
wiley   +1 more source

pH-triggered liposomal strategy for cisplatin in lung cancer therapy. [PDF]

Sci Rep
Demirbolat GM, Cakirli E, Saglam AB, Sarigul-Ozbek S, Abas BI, Cevik O.   +5 more
europepmc   +1 more source

Gankyrin‐Protein Interactions in GI Cancers: A Novel Target of New Therapeutics

Chronic Diseases and Translational Medicine, EarlyView.
ABSTRACT Gankyrin (PSMD10) is a 25 kDa oncogenic protein and regulatory subunit of the 26S proteasome, characterized by a sevenfold ankyrin repeat domain. Gankyrin is overexpressed in various malignancies, particularly gastrointestinal (GI) cancers. Gankyrin contributes to tumorigenesis by modulating key signaling pathways and engaging in oncogenic ...
Shuang Li, Yuky Lam, Aaron Muth, Zhe‐Sheng Chen, Shanzhi Wang   +4 more
wiley   +1 more source

Regulation of cisplatin resistance in lung cancer by epigenetic mechanisms. [PDF]

Clin Epigenetics
Yu X, Jia L, Tang Q, Zhou Q, Wang G, Wang S.   +5 more
europepmc   +1 more source

Nanogel‐Mediated Immunotherapy to Tackle Cancer and Inflammatory Diseases

ChemistryEurope, EarlyView.
Nanogels formed through self‐assembly, microemulsion, or precipitation polymerization method enable precise delivery of immunotherapeutic factors and immune cell targeting, thus effectively modulating immune responses. This review highlights recent advances in stimuli‐responsive nanogel design, underlying mechanisms, and their potentials to tackle ...
Ziwen Zhang, Jinxia Wang, Guang‐Zhi Jin, István Bányai, Dzmitry Shcharbin, Ivan Stoikov, Mingwu Shen, Xiangyang Shi   +7 more
wiley   +1 more source